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A. Ziegler · SciRah

Researcher profile · Semantic Scholar

A. Ziegler

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A. Ziegler — researcher profile on SciRah

h-index: 75
Works: 360
Citations: 33K

Most-cited papers

ranger: A Fast Implementation of Random Forests for High Dimensional Data in C++ and R
Marvin N. Wright, A. Ziegler
20153,764 citations Open access
Semantic Scholar
Mining data with random forests: current options for real‐world applications
A. Ziegler, I. König
2014WIREs Data Mining Knowl. Discov.271 citations
Semantic Scholar
An Introduction to Statistical Learning with Applications. R. G. James, D. Witten, T. Hastie, and R. Tibshirani (2013). Berlin: Springer. 440 pages, ISBN: 978‐1‐4614‐7138‐7.
A. Ziegler
2016264 citations
Semantic Scholar
Unbiased split variable selection for random survival forests using maximally selected rank statistics
Marvin N. Wright, Theresa Dankowski, A. Ziegler
2016Statistics in Medicine155 citations Open access
Semantic Scholar
Low-Frequency and Rare-Coding Variation Contributes to Multiple Sclerosis Risk
M. Mitrovic, N. Patsopoulos, Ashley H. Beecham, Theresa Dankowski +130 more
2018bioRxiv144 citations Open access
Semantic Scholar
Novel multiple sclerosis susceptibility loci implicated in epigenetic regulation
T. Andlauer, D. Buck, G. Antony, A. Bayas +80 more
2016Science Advances143 citations Open access
Semantic Scholar
Removing Batch Effects from Longitudinal Gene Expression - Quantile Normalization Plus ComBat as Best Approach for Microarray Transcriptome Data
C. Müller, A. Schillert, Caroline Röthemeier, D. Trégouët +11 more
2016PLoS ONE135 citations Open access
Semantic Scholar
On the use of Harrell's C for clinical risk prediction via random survival forests
M. Schmid, Marvin N. Wright, A. Ziegler
2015Expert systems with applications118 citations Open access
Semantic Scholar
Large-scale genome-wide analysis identifies genetic variants associated with cardiac structure and function
Philipp S. Wild, Janine F. Felix, A. Schillert, A. Teumer +120 more
2017Journal of Clinical Investigation117 citations Open access
Semantic Scholar
Safety and efficacy of mTOR inhibitor treatment in patients with tuberous sclerosis complex under 2 years of age – a multicenter retrospective study
Afshin Saffari, I. Brösse, A. Wiemer-Kruel, B. Wilken +20 more
2019Orphanet Journal of Rare Diseases116 citations Open access
Semantic Scholar
BiomarCaRE: rationale and design of the European BiomarCaRE project including 300,000 participants from 13 European countries
T. Zeller, M. Hughes, T. Tuovinen, A. Schillert +13 more
2014European Journal of Epidemiology110 citations Open access
Semantic Scholar
How to Include Chromosome X in Your Genome‐Wide Association Study
I. König, C. Loley, J. Erdmann, A. Ziegler
2014Genetic Epidemiology108 citations Open access
Semantic Scholar
Probability estimation with machine learning methods for dichotomous and multicategory outcome: Theory
Jochen Kruppa, Yu-Feng Liu, G. Biau, M. Kohler +3 more
2014Biometrical journal. Biometrische Zeitschrift96 citations
Semantic Scholar
European ad-hoc consensus statement on gene replacement therapy for spinal muscular atrophy
Jan Kirschner, N. Butoianu, N. Goemans, J. Haberlova +9 more
2020European journal of paediatric neurology90 citations Open access
Semantic Scholar
Risk prediction with machine learning and regression methods
E. Steyerberg, T. van der Ploeg, B. van Calster, Erasmus Mc +8 more
2014Biometrical journal. Biometrische Zeitschrift83 citations
Semantic Scholar
Treatment choices and neuropsychological symptoms of a large cohort of early MS
O. von Bismarck, Theresa Dankowski, B. Ambrosius, N. Heßler +28 more
2018Neurology: Neuroimmunology & Neuroinflammation76 citations Open access
Semantic Scholar
Probability estimation with machine learning methods for dichotomous and multicategory outcome: Applications
Jochen Kruppa, Yu-Feng Liu, H. Diener, T. Holste +3 more
2014Biometrical journal. Biometrische Zeitschrift68 citations
Semantic Scholar
Defining the clinical, molecular and imaging spectrum of adaptor protein complex 4-associated hereditary spastic paraplegia.
D. Ebrahimi-Fakhari, Julian Teinert, Robert Behne, Miriam Wimmer +84 more
2020Brain : a journal of neurology65 citations Open access
Semantic Scholar
Hypofractionation with simultaneous integrated boost for early breast cancer
K. Dellas, R. Vonthein, J. Zimmer, S. Dinges +7 more
2014Strahlentherapie und Onkologie (Print)64 citations
Semantic Scholar
Calibrating random forests for probability estimation
Theresa Dankowski, A. Ziegler
2016Statistics in Medicine62 citations Open access
Semantic Scholar
Genome‐wide association study in musician's dystonia: A risk variant at the arylsulfatase G locus?
K. Lohmann, A. Schmidt, A. Schillert, Susen Winkler +36 more
2014Movement Disorders56 citations Open access
Semantic Scholar
Genome‐wide association study identifies new susceptibility loci for cutaneous lupus erythematosus
M. Kunz, I. König, A. Schillert, Jochen Kruppa +22 more
2015Experimental Dermatology55 citations
Semantic Scholar
Genome-Wide Association Study of L-Arginine and Dimethylarginines Reveals Novel Metabolic Pathway for Symmetric Dimethylarginine
N. Lüneburg, W. Lieb, T. Zeller, Ming-Huei Chen +40 more
2014Circulation: Cardiovascular Genetics53 citations Open access
Semantic Scholar
Cerebrospinal fluid proteomic profiling in nusinersen‐treated patients with spinal muscular atrophy
T. Kessler, P. Latzer, Dominic Schmid, U. Warnken +9 more
2020Journal of Neurochemistry51 citations Open access
Semantic Scholar
Pathogenic WDFY3 variants cause neurodevelopmental disorders and opposing effects on brain size.
D. Le Duc, C. Giulivi, S. Hiatt, Eleonora Napoli +43 more
2019Brain : a journal of neurology51 citations Open access
Semantic Scholar
Transcriptome-Wide Analysis Identifies Novel Associations With Blood Pressure
T. Zeller, C. Schurmann, K. Schramm, C. Müller +37 more
2017HYPERTENSION46 citations Open access
Semantic Scholar
An omics-based strategy using coenzyme Q10 in patients with Parkinson’s disease: concept evaluation in a double-blind randomized placebo-controlled parallel group trial
Jannik Prasuhn, N. Bruggemann, N. Heßler, D. Berg +7 more
2019Neurological Research and Practice38 citations Open access
Semantic Scholar
Extensive alterations of the whole-blood transcriptome are associated with body mass index: results of an mRNA profiling study involving two large population-based cohorts
G. Homuth, S. Wahl, C. Müller, C. Schurmann +34 more
2015BMC Medical Genomics35 citations Open access
Semantic Scholar
Applied Missing Data Analysis in the Health Sciences. X.‐H. Zhou, C. Zhou, D. Liu, and X. Ding (2014). Hoboken: John Wiley & Sons. 256 pages, ISBN: 978‐0‐470‐52381‐0 (hardback); ISBN: 978‐1‐118‐57364‐8 (eBook).
H. Mwambi, A. Ziegler
201534 citations
Semantic Scholar
Support Vector Machines for Survival Analysis with R
C. Fouodo, I. König, C. Weihs, A. Ziegler +1 more
2018The R Journal33 citations Open access
Semantic Scholar
Development and validation of a melanoma risk score based on pooled data from 16 case-control studies
J. Davies, Yu-Mei Chang, D. Bishop, B. Armstrong +28 more
2015Cancer Epidemiology, Biomarkers and Prevention33 citations Open access
Semantic Scholar
CASPR2 autoimmunity in children expanding to mild encephalopathy with hypertension
S. Syrbe, G. Stettner, Julien F. Bally, I. Borggraefe +15 more
2020Neurology32 citations
Semantic Scholar
Novel challenges in spinal muscular atrophy – How to screen and whom to treat?
Afshin Saffari, S. Kolker, G. Hoffmann, M. Weiler +1 more
2018Annals of Clinical and Translational Neurology32 citations Open access
Semantic Scholar
Biallelic and monoallelic variants in PLXNA1 are implicated in a novel neurodevelopmental disorder with variable cerebral and eye anomalies
G. Dworschak, J. Punetha, Jeshurun C. Kalanithy, E. Mingardo +62 more
2021Genetics in Medicine31 citations Open access
Semantic Scholar
Low-level mitochondrial heteroplasmy modulates DNA replication, glucose metabolism and lifespan in mice
M. Hirose, P. Schilf, Y. Gupta, K. Zarse +26 more
2017bioRxiv31 citations Open access
Semantic Scholar
Mendelian Randomization versus Path Models: Making Causal Inferences in Genetic Epidemiology
A. Ziegler, H. Mwambi, I. König
2015Human Heredity31 citations
Semantic Scholar
Mitochondrial mutation m.1555A>G as a risk factor for failed newborn hearing screening in a large cohort of preterm infants
W. Göpel, Sandra Berkowski, Michael H. Preuss, A. Ziegler +6 more
2014BMC Pediatrics31 citations Open access
Semantic Scholar
Molecular Characterization of the NLRC4 Expression in Relation to Interleukin-18 Levels
T. Zeller, Tina Haase, C. Müller, Helene Riess +25 more
2015Circulation: Cardiovascular Genetics27 citations Open access
Semantic Scholar
Quantitative MR neurography biomarkers in 5q-linked spinal muscular atrophy
Jennifer Kollmer, T. Hilgenfeld, A. Ziegler, Afshin Saffari +8 more
2019Neurology26 citations
Semantic Scholar
Novel variants and clinical symptoms in four new ALG3‐CDG patients, review of the literature, and identification of AAGRP‐ALG3 as a novel ALG3 variant with alanine and glycine‐rich N‐terminus
N. Himmelreich, Bianca Dimitrov, Virginia Geiger, M. Zielonka +20 more
2019Human Mutation26 citations Open access
Semantic Scholar
Comments on: Association Study between Coronary Artery Disease and rs1333049 and rs10757274 Polymorphisms at 9p21 Locus in South-West Iran
Preuß Michael H., A. Ziegler
2016Cell journal22 citations
Semantic Scholar
Random forests for survival analysis using maximally selected rank statistics
Marvin N. Wright, Theresa Dankowski, A. Ziegler
201622 citations
Semantic Scholar
Comparison of pre-processing methods for multiplex bead-based immunoassays
T. K. Rausch, A. Schillert, A. Ziegler, Angelika Lüking +2 more
2016BMC Genomics21 citations Open access
Semantic Scholar
Lifespan effects of mitochondrial mutations
M. Hirose, P. Schilf, Y. Gupta, Marvin N. Wright +6 more
2016Nature19 citations
Semantic Scholar
Successful Replication of GWAS Hits for Multiple Sclerosis in 10,000 Germans Using the Exome Array
Theresa Dankowski, D. Buck, T. Andlauer, G. Antony +48 more
2015Genetic Epidemiology19 citations
Semantic Scholar
Update of the effect estimates for common variants associated with carotid intima media thickness within four independent samples: The Bonn IMT Family Study, the Heinz Nixdorf Recall Study, the SAPHIR Study and the Bruneck Study.
M. H. Geisel, S. Coassin, N. Heßler, Marcus Bauer +22 more
2016Atherosclerosis18 citations
Semantic Scholar
Preprocessing and Quality Control for Whole-Genome Sequences from the Illumina HiSeq X Platform.
Marvin N. Wright, D. Gola, A. Ziegler
2017Methods in molecular biology17 citations
Semantic Scholar
Association between SNPs in defined functional pathways and risk of early or late toxicity as well as individual radiosensitivity
Sebastian Reuther, S. Szymczak, A. Raabe, K. Borgmann +4 more
2014Strahlentherapie und Onkologie (Print)17 citations
Semantic Scholar
Hypo-fractionated SBRT for localized prostate cancer: a German bi-center single treatment group feasibility trial
P. Jiang, K. Krockenberger, R. Vonthein, Jane Tereszczuk +16 more
2017Radiation Oncology16 citations Open access
Semantic Scholar
A comprehensive evaluation of collapsing methods using simulated and real data: excellent annotation of functionality and large sample sizes required
C. Dering, I. König, Laura B. Ramsey, M. Relling +2 more
2014Frontiers in Genetics16 citations Open access
Semantic Scholar

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