L. Brand

Most-cited papers

1. Resonance energy transfer: methods and applications.

   Pengguang Wu, L. Brand

   1994Analytical Biochemistry1,235 citations Open access

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2. Time-resolved fluorescence of proteins.

   J. Beechem, L. Brand

   1985Annual Review of Biochemistry711 citations

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3. Simultaneous analysis of multiple fluorescence decay curves: A global approach

   J. Knutson, J. Beechem, L. Brand

   1983521 citations

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4. Nanosecond time-dependent fluorescence depolarization of diphenylhexatriene in dimyristoyllecithin vesicles and the determination of "microviscosity".

   Lydia A. Chen, R. Dale, S. Roth, L. Brand

   1977Journal of Biological Chemistry274 citations Open access

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5. [17] Time-resolved fluorescence measurements

   M. Badea, L. Brand

   1979231 citations

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6. Rotational relaxation of the "microviscosity" probe diphenylhexatriene in paraffin oil and egg lecithin vesicles.

   R. Dale, L.-A. Chen, L. Brand

   1977Journal of Biological Chemistry219 citations Open access

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7. Decay-associated fluorescence spectra and the heterogeneous emission of alcohol dehydrogenase.

   J. Knutson, D. Walbridge, L. Brand

   1982Biochemistry179 citations

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8. Analysis of two-state excited-state reactions. The fluorescence decay of 2-naphthol

   W. Laws, L. Brand

   1979160 citations

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9. Fluorescence decay studies of anisotropic rotations of small molecules

   Mary D. Barkley, A. Kowalczyk, L. Brand

   1981159 citations

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10. Time-resolved fluorescence of the two tryptophans in horse liver alcohol dehydrogenase.

    J. B. Alexander Ross, Carl J. Schmidt, L. Brand

    1981Biochemistry147 citations

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11. Profluorescent protease substrates: intramolecular dimers described by the exciton model.

    B. Packard, D. Toptygin, A. Komoriya, L. Brand

    1996Proceedings of the National Academy of Sciences of the United States of America136 citations Open access

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12. Global resolution of heterogeneous decay by phase/modulation fluorometry: mixtures and proteins

    J. Beechem, J. Knutson, J. B. Alexander Ross, B. W. Turner +1 more

    1983131 citations

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13. Time-resolved fluorescence and anisotropy decay of the tryptophan in adrenocorticotropin-(1-24).

    J. B. Alexander Ross, K. Rousslang, L. Brand

    1981Biochemistry130 citations

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14. Global analysis of fluorescence decay surfaces: excited-state reactions

    J. Beechem, M. Ameloot, L. Brand

    1985118 citations

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15. Orientation factor in steady-state and time-resolved resonance energy transfer measurements.

    Pengguang Wu, L. Brand

    1992Biochemistry116 citations

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16. The Global Analysis of Fluorescence Intensity and Anisotropy Decay Data: Second-Generation Theory and Programs

    J. Beechem, E. Gratton, M. Ameloot, J. Knutson +1 more

    2002111 citations

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17. Global and Target Analysis of Complex Decay Phenomena

    J. Beechem, M. Ameloot, L. Brand

    1985110 citations

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18. Time-resolved fluorescence and 1H NMR studies of tyrosine and tyrosine analogues: correlation of NMR-determined rotamer populations and fluorescence kinetics.

    W. Laws, J. B. Alexander Ross, Herman R. Wyssbrod, J. Beechem +2 more

    1986Biochemistry90 citations

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19. Effect of the Solvent Refractive Index on the Excited-State Lifetime of a Single Tryptophan Residue in a Protein

    D. Toptygin, Regina S. Savtchenko, N. Meadow, S. Roseman +1 more

    200270 citations

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20. Excited state proton transfer reactions of acridine studied by nanosecond fluorometry

    A. Gafni, L. Brand

    197867 citations

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21. Mechanism of the Efficient Tryptophan Fluorescence Quenching in Human γD-Crystallin Studied by Time-Resolved Fluorescence

    Jie-Jin Chen, D. Toptygin, L. Brand, J. King

    2008Biochemistry64 citations Open access

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22. Excited-state proton transfer of equilenin and dihydroequilenin: interaction with bilayer vesicles.

    L. Davenport, J. Knutson, L. Brand

    1986Biochemistry61 citations

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23. Time-resolved fluorescence measurements.

    M. Badea, L. Brand

    1979Methods in Enzymology60 citations

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24. Resolution of absorption spectra of rhodamine 6G aggregates in aqueous solution using the law of mass action

    D. Toptygin, B. Packard, L. Brand

    199755 citations Open access

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25. Homogeneous Spectrally- and Time-Resolved Fluorescence Emission from Single-Tryptophan Mutants of IIAGlc Protein

    D. Toptygin, Regina S. Savtchenko, N. Meadow, L. Brand

    200154 citations

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26. Nanosecond relaxation dynamics of protein GB1 identified by the time-dependent red shift in the fluorescence of tryptophan and 5-fluorotryptophan.

    D. Toptygin, A. Gronenborn, L. Brand

    2006Journal of Physical Chemistry B53 citations

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27. Ultrafast fluorescence dynamics of tryptophan in the proteins monellin and IIAGlc.

    Jianhua Xu, D. Toptygin, Karen J Graver, Rebecca A Albertini +6 more

    2006Journal of the American Chemical Society52 citations

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28. Aromatic interactions in homeodomains contribute to the low quantum yield of a conserved, buried tryptophan

    Vikas Nanda, L. Brand

    2000Proteins: Structure, Function, and Bioinformatics52 citations

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29. Interterminal distance and flexibility of a triantennary glycopeptide as measured by resonance energy transfer.

    K. Rice, R.-G. Wu, L. Brand, Y. Lee

    1991Biochemistry51 citations

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30. Spectrally- and time-resolved fluorescence emission of indole during solvent relaxation: a quantitative model

    D. Toptygin, L. Brand

    200049 citations Open access

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31. Femtosecond Fluorescence Spectra of Tryptophan in Human γ-Crystallin Mutants: Site-Dependent Ultrafast Quenching

    Jianhua Xu, Jie-Jin Chen, D. Toptygin, O. Tcherkasskaya +4 more

    2009Journal of the American Chemical Society44 citations Open access

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32. The effects of conformational heterogeneity on the binding of the Notch intracellular domain to effector proteins: a case of biologically tuned disorder.

    A. Bertagna, D. Toptygin, L. Brand, D. Barrick

    2008Biochemical Society Transactions44 citations

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33. Anisotropy decay associated fluorescence spectra and analysis of rotational heterogeneity. 1. Theory and applications.

    J. Knutson, L. Davenport, L. Brand

    1986Biochemistry43 citations

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34. Nanosecond relaxation processes in liposomes.

    M. Badea, Robert P. Detoma, L. Brand

    1978Biophysical Journal42 citations Open access

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35. Structural Characteristics of Fluorophores That Form Intramolecular H-Type Dimers in a Protease Substrate†

    B. Packard, A. Komoriya, D. Toptygin, L. Brand

    199740 citations

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36. Sugar transport by the bacterial phosphotransferase system. Characterization of the Escherichia coli enzyme I monomer/dimer transition kinetics by fluorescence anisotropy.

    F. Chauvin, L. Brand, S. Roseman

    1994Journal of Biological Chemistry40 citations

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37. Compartmental modeling of excited-state reactions: identifiabilityof the rate constants from fluorecences decay surfaces

    M. Ameloot, J. Beechem, L. Brand

    198639 citations

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38. GLOBAL ANALYSIS OF FLUORESCENCE DECAY: APPLICATIONS TO SOME UNUSUAL EXPERIMENTAL AND THEORETICAL STUDIES

    J. Beechem, L. Brand

    1986Photochemistry and Photobiology38 citations

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39. Anisotropy decay associated fluorescence spectra and analysis of rotational heterogeneity. 2. 1,6-Diphenyl-1,3,5-hexatriene in lipid bilayers.

    L. Davenport, J. Knutson, L. Brand

    1986Biochemistry38 citations

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40. Experimental determination of oligosaccharide three-dimensional structure

    K. Rice, Pengguang Wu, L. Brand, Yuan-Chuan Lee

    199337 citations

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41. Compact denatured state of a staphylococcal nuclease mutant by guanidinium as determined by resonance energy transfer.

    E. James, Pengguang Wu, W. Stites, L. Brand

    1992Biochemistry37 citations

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42. Global analysis of multiple dye fluorescence anisotropy experiments on proteins.

    J. Beechem, J. Knutson, L. Brand

    1986Biochemical Society Transactions36 citations

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43. Picosecond protein dynamics: the origin of the time-dependent spectral shift in the fluorescence of the single Trp in the protein GB1.

    D. Toptygin, T. Woolf, L. Brand

    2010Journal of Physical Chemistry B35 citations

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44. Conformational flexibility in a staphylococcal nuclease mutant K45C from time-resolved resonance energy transfer measurements.

    Pengguang Wu, L. Brand

    1994Biochemistry35 citations

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45. Modification of oligosaccharide antenna flexibility induced by exoglycosidase trimming.

    Kevin G. Rice, Pengguang Wu, L. Brand, Yuan-Chuan Lee

    1993Biochemistry34 citations

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46. Simultaneous analysis of multiple fluorescence decay curves by Laplace transforms. Deconvolution with reference or excitation profiles.

    M. Ameloot, J. Beechem, L. Brand

    1986Biophysical Chemistry34 citations

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47. Fluorescence decay and depolarization in membranes

    D. Toptygin, J. Svobodová, I. Konopásek, L. Brand

    199233 citations

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48. Excited-State Proton Transfer

    L. Brand, W. Laws

    198333 citations

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49. Intramolecular Resonance Dipole−Dipole Interactions in a Profluorescent Protease Substrate

    B. Packard, D. Toptygin, A. Komoriya, L. Brand

    199831 citations

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50. Investigation of the nature of enzyme--coenzyme interactions in binary and ternary complexes of liver alcohol dehydrogenase with coenzymes, coenzyme analogues, and substrate analogues by ultraviolet absorption and phosphorescence spectroscopy.

    S. Subramanian, J. B. Alexander Ross, Philip D. Ross, L. Brand

    1981Biochemistry27 citations

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