Thomas S. O’Leary

Most-cited papers

1. Effects of MYBPC3 loss of function mutations preceding hypertrophic cardiomyopathy.

   A. Helms, Vi T. Tang, Thomas S. O’Leary, Sabrina Friedline +10 more

   2019JCI Insight88 citations Open access

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2. Defects in the Proteome and Metabolome in Human Hypertrophic Cardiomyopathy

   M. Previs, Thomas S. O’Leary, M. Morley, B. Palmer +9 more

   2022Circulation: Heart Failure78 citations Open access

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3. MYBPC3 truncation mutations enhance actomyosin contractile mechanics in human hypertrophic cardiomyopathy

   Thomas S. O’Leary, J. Snyder, S. Sadayappan, S. Day +1 more

   2018Journal of Molecular and Cellular Cardiology59 citations Open access

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4. Physiologic biomechanics enhance reproducible contractile development in a stem cell derived cardiac muscle platform

   Yao-Chang Tsan, Samuel J. DePalma, Yan-Ting Zhao, Adela Capilnasiu +15 more

   2021Nature Communications44 citations Open access

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5. Skeletal MyBP-C isoforms tune the molecular contractility of divergent skeletal muscle systems

   Amy Li, Shane R. Nelson, Sheema Rahmanseresht, F. Braet +8 more

   2019Proceedings of the National Academy of Sciences of the United States of America43 citations Open access

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6. The N terminus of myosin-binding protein C extends toward actin filaments in intact cardiac muscle

   Sheema Rahmanseresht, K. Lee, Thomas S. O’Leary, James W. McNamara +5 more

   2021The Journal of General Physiology39 citations Open access

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7. CryoEM structure of Drosophila flight muscle thick filaments at 7 Å resolution

   N. Daneshparvar, D. Taylor, Thomas S. O’Leary, H. Rahmani +3 more

   2020Life Science Alliance26 citations Open access

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8. Myosin-binding protein H-like regulates myosin-binding protein distribution and function in atrial cardiomyocytes

   David Y. Barefield, Paola Tonino, Kathleen C. Woulfe, Sheema Rahmanseresht +7 more

   2023Proceedings of the National Academy of Sciences of the United States of America17 citations Open access

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9. Cardiac Myosin Filaments are Maintained by Stochastic Protein Replacement

   N. Wood, Colleen M. Kelly, Thomas S. O’Leary, Jody L. Martin +1 more

   2022Molecular & Cellular Proteomics12 citations Open access

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10. Biomechanics and Myofibrillar Alignment Enhance Contractile Development and Reproducibility in Stem Cell Derived Cardiac Muscle

    Yao-Chang Tsan, Yan-Ting Zhao, Samuel J. DePalma, Adela Capilnasiu +13 more

    2021bioRxiv1 citations Open access

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11. Metabolic and Proteomic Defects in Human Hypertrophic Cardiomyopathy

    M. Previs, Thomas S. O’Leary, N. Wood, M. Morley +10 more

    2021bioRxiv0 citations Open access

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12. Skeletal Myosin-Binding Protein C Isoforms Differentially Regulate Fast- and Slow-Twitch Skeletal Muscle Function

    Shane R. Nelson, Amy Li, Sheema Rahmanseresht, F. Braet +8 more

    20200 citations Open access

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13. Why the Interacting Heads Motif is not Observed in Isolated, Relaxed Thick Filaments of Drosophila Melanogaster

    N. Daneshparvar, M. Previs, Thomas S. O’Leary, D. Taylor +3 more

    20200 citations Open access

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14. Replacement of Myosin Molecules within Cardiac Thick Filaments in Intact Mouse Hearts

    M. Previs, Jody L. Martin, Jeffrey L. Spees, Thomas S. O’Leary

    20200 citations Open access

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15. Myosin Binding Protein H-Like Regulates Myofilament Content in Atrial and a Subset of Ventricular Conduction System Cardiomyocytes

    David Y. Barefield, Sheema Rahmanseresht, Thomas S. O’Leary, Jordan J. Sell +4 more

    2019Biophysical Journal0 citations Open access

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