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C. Varricchio · SciRah

Researcher profile · Semantic Scholar

C. Varricchio

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C. Varricchio — researcher profile on SciRah

h-index: 14
Works: 35
Citations: 622

Most-cited papers

Identification of SARS-CoV-2 inhibitors targeting Mpro and PLpro using in-cell-protease assay
Anoop Narayanan, M. Narwal, Sydney A. Majowicz, C. Varricchio +5 more
2022Communications Biology198 citations Open access
Semantic Scholar
NMNAT2 is a druggable target to drive neuronal NAD production
James R. Tribble, Melissa Jöe, C. Varricchio, Amin Otmani +12 more
2024Nature Communications42 citations Open access
Semantic Scholar
Structure Property Relationships of N-Acylsulfonamides and Related Bioisosteres
Karol R. Francisco, C. Varricchio, Thomas J. Paniak, M. Kozlowski +2 more
2021European journal of medicinal chemistry36 citations Open access
Semantic Scholar
In vitro Topical Delivery of Chlorhexidine to the Cornea: Enhancement using Drug-Loaded Contact Lenses and β-Cyclodextrin Complexation, and the Importance of Simulating Tear Irrigation.
Melissa G Hewitt, Peter W J Morrison, Hannah M Boostrom, Siân R. Morgan +8 more
2020Molecular Pharmaceutics31 citations Open access
Semantic Scholar
PINK1-Dependent Mitophagy Inhibits Elevated Ubiquitin Phosphorylation Caused by Mitochondrial Damage
Olivia A. Lambourne, S. Bell, Léa P. Wilhelm, Erika B Yarbrough +10 more
2023Journal of Medicinal Chemistry26 citations Open access
Semantic Scholar
The ying and yang of idebenone: Not too little, not too much - cell death in NQO1 deficient cells and the mouse retina.
C. Varricchio, K. Beirne, C. Heard, B. Newland +3 more
2019Free Radical Biology & Medicine25 citations Open access
Semantic Scholar
Monoamine Oxidase (MAO-N) Biocatalyzed Synthesis of Indoles from Indolines Prepared via Photocatalytic Cyclization/Arylative Dearomatization
Fei Zhao, Domiziana Masci, Salvatore Ferla, C. Varricchio +5 more
2020ACS Catalysis24 citations Open access
Semantic Scholar
Geneticin shows selective antiviral activity against SARS-CoV-2 by interfering with programmed −1 ribosomal frameshifting
C. Varricchio, Gregory Mathez, T. Pillonel, C. Bertelli +4 more
2022bioRxiv23 citations Open access
Semantic Scholar
A Novel Dual Action Monolithic Thermosetting Hydrogel Loaded With Lidocaine And Metronidazole As a Potential Treatment For Alveolar Osteitis.
Lena Bender, Hannah M Boostrom, C. Varricchio, Marika Zuanon +4 more
2020European journal of pharmaceutics and biopharmaceutics23 citations Open access
Semantic Scholar
Focal drug administration via heparin-containing cryogel microcarriers reduces cancer growth and metastasis.
B. Newland, C. Varricchio, Yvonne Körner, Franziska Hoppe +9 more
2020Carbohydrate Polymers21 citations Open access
Semantic Scholar
Evaluation of Structure-Activity Relationship of Microtubule (MT)-Targeting 1,2,4-Triazolo[1,5-a]pyrimidines Identifies New Candidates for Neurodegenerative Tauopathies
Killian Oukoloff, Goodwell Nzou, C. Varricchio, Bobby Lucero +12 more
2021Journal of Medicinal Chemistry20 citations Open access
Semantic Scholar
Biocatalytic and Chemo-Enzymatic Synthesis of Quinolines and 2-Quinolones by Monoamine Oxidase (MAO-N) and Horseradish Peroxidase (HRP) Biocatalysts
Haoyue Xiang, Salvatore Ferla, C. Varricchio, A. Brancale +4 more
2023ACS Catalysis19 citations Open access
Semantic Scholar
Sulfonated cryogel scaffolds for focal delivery in ex-vivo brain tissue cultures.
Dimitri Eigel, Romy Schuster, M. J. Männel, J. Thiele +9 more
2021Biomaterials19 citations Open access
Semantic Scholar
A Time-Kill Assay Study on the Synergistic Bactericidal Activity of Pomegranate Rind Extract and Zn (II) against Methicillin-Resistant Staphylococcus aureus (MRSA), Staphylococcus epidermidis, Escherichia coli, and Pseudomonas aeruginosa
A. Alrashidi, M. Jafar, Niamh Higgins, C. Mulligan +5 more
2021Biomolecules17 citations Open access
Semantic Scholar
Computational Studies towards the Identification of Novel Rhodopsin-Binding Compounds as Chemical Chaperones for Misfolded Opsins
Gaia Pasqualetto, M. Schepelmann, C. Varricchio, Elisa Pileggi +7 more
2020Molecules14 citations Open access
Semantic Scholar
Discovery of Novel 2-Aniline-1,4-naphthoquinones as Potential New Drug Treatment for Leber's Hereditary Optic Neuropathy (LHON).
C. Varricchio, Kathy Beirne, Pascale Aeschlimann, C. Heard +3 more
2020Journal of Medicinal Chemistry14 citations Open access
Semantic Scholar
Targeted Reversible Covalent Modification of a Noncatalytic Lysine of the Krev Interaction Trapped 1 Protein Enables Site-Directed Screening for Protein–Protein Interaction Inhibitors
Karol R. Francisco, Jessica Bruystens, C. Varricchio, Sara McCurdy +8 more
2023ACS Pharmacology & Translational Science12 citations Open access
Semantic Scholar
A Composite System Based upon Hydroxypropyl Cyclodextrins and Soft Hydrogel Contact Lenses for the Delivery of Therapeutic Doses of Econazole to the Cornea, In Vitro
Anepmete Wong, M. Fallon, Vildan Celiksoy, Salvatore Ferla +4 more
2022Pharmaceutics12 citations Open access
Semantic Scholar
Microtubule-Stabilizing 1,2,4-Triazolo[1,5-a]pyrimidines as Candidate Therapeutics for Neurodegenerative Disease: Matched Molecular Pair Analyses and Computational Studies Reveal New Structure–Activity Insights
Thibault Alle, C. Varricchio, Yue-Mang Yao, Bobby Lucero +13 more
2022Journal of Medicinal Chemistry12 citations Open access
Semantic Scholar
Design, synthesis, and biological investigation of selective human carbonic anhydrase II, IX, and XII inhibitors using 7-aryl/heteroaryl triazolopyrimidines bearing a sulfanilamide scaffold
R. Romagnoli, Tiziano De Ventura, S. Manfredini, E. Baldini +7 more
2023Journal of Enzyme Inhibition and Medicinal Chemistry9 citations Open access
Semantic Scholar
Rational design of novel nucleoside analogues reveals potent antiviral agents for EV71.
Martina Salerno, C. Varricchio, Federica Bevilacqua, Dirk Jochmans +4 more
2022European journal of medicinal chemistry9 citations Open access
Semantic Scholar
Ligand-based rational design, synthesis and evaluation of novel potential chemical chaperones for opsin.
Gaia Pasqualetto, Elisa Pileggi, M. Schepelmann, C. Varricchio +3 more
2021European journal of medicinal chemistry7 citations Open access
Semantic Scholar
Design, Synthesis, and Evaluation of An Anti-trypanosomal [1,2,4]Triazolo[1,5-a]pyrimidine Probe for Photoaffinity Labeling Studies
Bobby Lucero, Karol R. Francisco, C. Varricchio, Lawrence J. Liu +5 more
2024ChemMedChem5 citations Open access
Semantic Scholar
Structure-Activity Relationships, Tolerability and Efficacy of Microtubule-Active 1,2,4-Triazolo[1,5-a]pyrimidines as Potential Candidates to Treat Human African Trypanosomiasis
Ludovica Monti, Lawrence J. Liu, C. Varricchio, Bobby Lucero +8 more
2023bioRxiv4 citations Open access
Semantic Scholar
Structure–Activity Relationship Studies on Novel Antiviral Agents for Norovirus Infections
Salvatore Ferla, C. Varricchio, W. Knight, Pui-Kei Ho +11 more
2021Microorganisms2 citations Open access
Semantic Scholar
Structure-Activity Relationships, Tolerability and Efficacy of Microtubule-Active 1,2,4-Triazolo[1,5-a]pyrimidines as Potential Candidates to Treat Human African Trypanosomiasis
Ludovica Monti, Lawrence J. Liu, C. Varricchio, Bobby Lucero +8 more
2023ChemMedChem1 citations Open access
Semantic Scholar
Development of a nanomedicine approach to improve the therapeutic index of bexarotene
Siân Rizzo, Carola Pepe, Thibault Albert, Gabriel Braux +6 more
2026bioRxiv0 citations Open access
Semantic Scholar
Structure-Activity Relationship and Target Investigation of Thiophen-2-yl-Pyrimidines against Schistosoma species
Karol R. Francisco, Bobby Lucero, Darius J Yohannan, C. Varricchio +11 more
2025bioRxiv0 citations Open access
Semantic Scholar
Author Correction: NMNAT2 is a druggable target to drive neuronal NAD production
James R. Tribble, Melissa Jöe, C. Varricchio, Amin Otmani +12 more
2024Nature Communications0 citations Open access
Semantic Scholar
Front Cover: Structure‐Activity Relationships, Tolerability and Efficacy of Microtubule‐Active 1,2,4‐Triazolo[1,5‐a]pyrimidines as Potential Candidates to Treat Human African Trypanosomiasis (ChemMedChem 20/2023)
Ludovica Monti, Lawrence J. Liu, C. Varricchio, Bobby Lucero +8 more
2023ChemMedChem0 citations
Semantic Scholar
Title: The discovery of novel 2- aniline-1,4 naphthoquinones as potential new drug treatment for Leber’s hereditary optic neuropathy ( LHON)
C. Varricchio, Kathy Beirne, Pascale Aeschlimann, C. Heard +3 more
20230 citations
Semantic Scholar
Geneticin shows selective antiviral activity against SARS-CoV-2 by targeting programmed -1 ribosomal frameshifting
C. Varricchio, Gregory Mathez, Laurent Kaiser, C. Tapparel +2 more
20220 citations
Semantic Scholar
Corrigendum to "structure property relationships of N-Acylsulfonamides and related bioisosteres" European journal of medicinal chemistry, 218 (2021), 113399.
Karol R. Francisco, C. Varricchio, Thomas J. Paniak, M. Kozlowski +2 more
2021European journal of medicinal chemistry0 citations
Semantic Scholar
Novel drug therapy for mitochondrial optic neuropathy
C. Varricchio
20190 citations
Semantic Scholar
Drug Development For The Treatment Of Mitochondrial Optic Neuropathies
C. Varricchio
20170 citations
Semantic Scholar

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