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Ebtehal M. Husseiny · SciRah

Researcher profile · Semantic Scholar

Ebtehal M. Husseiny

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Ebtehal M. Husseiny — researcher profile on SciRah

h-index: 13
Works: 29
Citations: 507

Most-cited papers

Apoptosis induction, PARP-1 inhibition, and cell cycle analysis of leukemia cancer cells treated with novel synthetic 1,2,3-triazole-chalcone conjugates.
E. M. Othman, E. Fayed, Ebtehal M. Husseiny, Hamada S. Abulkhair
2022Bioorganic chemistry (Print)69 citations
Semantic Scholar
The effect of novel synthetic semicarbazone- and thiosemicarbazone-linked 1,2,3-triazoles on the apoptotic markers, VEGFR-2, and cell cycle of myeloid leukemia.
E. M. Othman, E. Fayed, Ebtehal M. Husseiny, Hamada S. Abulkhair
2022Bioorganic chemistry (Print)55 citations
Semantic Scholar
From triazolophthalazines to triazoloquinazolines: A bioisosterism-guided approach toward the identification of novel PCAF inhibitors with potential anticancer activity.
Mohamed H. El-Shershaby, Adel H. Ghiaty, A. Bayoumi, A. Al-Karmalawy +3 more
2021Bioorganic & Medicinal Chemistry54 citations Open access
Semantic Scholar
Synthesis, cytotoxicity of some pyrazoles and pyrazolo[1,5-a]pyrimidines bearing benzothiazole moiety and investigation of their mechanism of action.
Ebtehal M. Husseiny
2020Bioorganic chemistry (Print)42 citations
Semantic Scholar
Exploring the cytotoxic effect and CDK-9 inhibition potential of novel sulfaguanidine-based azopyrazolidine-3,5-diones and 3,5-diaminoazopyrazoles.
Ebtehal M. Husseiny, Hamada S. Abulkhair, Nehad M. El-Dydamony, K. E. Anwer
2023Bioorganic chemistry (Print)41 citations
Semantic Scholar
Rationale Design, Synthesis, Cytotoxicity Evaluation, and In silico Mechanistic Studies of Novel 1,2,3-Triazoles with Potential Anticancer Activity
E. M. Othman, E. Fayed, Ebtehal M. Husseiny, Hamada S. Abulkhair
2022New Journal of Chemistry32 citations
Semantic Scholar
Design, synthesis, and mechanistic insight of novel imidazolones as potential EGFR inhibitors and apoptosis inducers.
Fatma G. Abdulrahman, Hamada S. Abulkhair, Hoda S. El Saeed, Nehad M. El-Dydamony +1 more
2024Bioorganic chemistry (Print)23 citations
Semantic Scholar
Exploring 1,2,3-triazole-Schiff's base hybrids as innovative EGFR inhibitors for the treatment of breast cancer: In vitro and in silico study.
Nareman A. Nawareg, Asmaa S. A. Yassen, Ebtehal M. Husseiny, Magda A A El-Sayed +1 more
2025Bioorganic chemistry (Print)21 citations
Semantic Scholar
Novel imidazolone derivatives as potential dual inhibitors of checkpoint kinases 1 and 2: Design, synthesis, cytotoxicity evaluation, and mechanistic insights.
Yasmin S. Sheta, M. Sarg, Fatma G. Abdulrahman, E. S. Nossier +1 more
2024Bioorganic chemistry (Print)20 citations
Semantic Scholar
Exploration of quinoxaline derivatives as antimicrobial and anticancer agents
A. Bayoumi, Adel H. Ghiaty, Shimaa M. Abd-Elgilil, Ebtehal M. Husseiny +1 more
2019Journal of Heterocyclic Chemistry20 citations
Semantic Scholar
Molecular overlay-guided design of new CDK2 inhibitor thiazepinopurines: Synthesis, anticancer, and mechanistic investigations.
Ebtehal M. Husseiny, Hamada S. Abulkhair, A. Saleh, N. Altwaijry +2 more
2023Bioorganic chemistry (Print)19 citations
Semantic Scholar
Aminopyridone-linked benzimidazoles: a fragment-based drug design for the development of CDK9 inhibitors.
Ebtehal M. Husseiny, Hamada S. Abulkhair, S. El-Hddad, Nada Osama +1 more
2023Future Medicinal Chemistry15 citations
Semantic Scholar
Synthesis and Anticancer Evaluation of Some Novel Thiophene, Thieno[3,2‐ d ]pyrimidine, Thieno[3,2‐ b ]pyridine, and Thieno[3,2‐ e ][1,4]oxazepine Derivatives Containing Benzothiazole Moiety
A. Hassan, Ebtehal M. Husseiny
2019Journal of Heterocyclic Chemistry15 citations
Semantic Scholar
In vivo evaluation of novel synthetic pyrazolones as CDK9 inhibitors with enhanced pharmacokinetic properties.
Ebtehal M. Husseiny, Hamada S. Abulkhair, S. El‐Sebaey, Manal M Sayed +1 more
2024Future Medicinal Chemistry13 citations Open access
Semantic Scholar
Novel benzochromenes: design, synthesis, cytotoxicity, molecular docking and mechanistic investigations.
Fatma G. Abdulrahman, Hamada S. Abulkhair, Riham A Zidan, Asmaa I. Alwakeel +2 more
2024Future Medicinal Chemistry13 citations
Semantic Scholar
Mimicry of sorafenib: novel diarylureas as VEGFR2 inhibitors and apoptosis inducers in breast cancer
M. Ismail, Ebtehal M. Husseiny, Mona H. Ibrahim
2023New Journal of Chemistry13 citations
Semantic Scholar
Comparative Study of Conventional, Grinding, and Microwave‐Assisted Synthesis of Aminopyrazolones and Diaminopyrazoles: Exploring the Antitumor Activity, Dual CDK‐2/CA IX Inhibition Potential, and Apoptosis Induction
K. E. Anwer, Nehad M. El-Dydamony, Asmaa Saleh, N. Altwaijry +1 more
2025Drug development research (Print)6 citations
Semantic Scholar
Synthesis, Characterization and Anticancer Activity of Some Benzothiazole and Thiazole Derivatives
A. Hassan, M. Sarg, Ebtehal M. Husseiny
2020Journal of Advanced Pharmacy Research6 citations Open access
Semantic Scholar
Investigating the cytotoxicity, CDK-2 inhibition, mechanistic insights, in silico DFT and molecular docking studies of eco-friendly synthesized benzo[b]thiophene carbohydrazides
Ebtehal M. Husseiny, R. Ramadan, E. S. Nossier, Asmaa Saleh +2 more
2025Journal of Molecular Structure5 citations
Semantic Scholar
Synthesis and Exploration of New Imidazo[4,5‐c]Pyrazoles as Potent α ‐Amylase Inhibitors
Sara Nabil Shabaan, Fawzia Saleh Alshehri, Jinan Fadel al-Rasheed, S. El‐Sebaey +1 more
2023ChemistrySelect5 citations
Semantic Scholar
Comparison between conventional, grinding, and microwave synthesis of methylpyrazoles as VEGFR-2/HSP90 dual inhibitors.
Ebtehal M. Husseiny, R. Abdelnaby, N. Altwaijry, Asmaa Saleh +1 more
2025Future Medicinal Chemistry4 citations Open access
Semantic Scholar
Design, synthesis, anticancer activity, and mechanistic investigation of 4,5,6,7-tetrahydrobenzo[b]thiophene carboxamides as CDK-2 inhibitors: in vitro and in silico DFT and molecular docking study
K. E. Anwer, R. Ramadan, E. S. Nossier, N. Altwaijry +3 more
2026Journal of Enzyme Inhibition and Medicinal Chemistry3 citations Open access
Semantic Scholar
Design, synthesis, radiolabeling, and mechanistic insights of hydrazinyl imidazolones as broad spectrum antitumor agents with potential carbonic anhydrase inhibition: In vitro, in vivo, and in silico studies.
Ebtehal M. Husseiny, M. Sarg, Yasmin S. Sheta, Manal M Sayed +1 more
2025European journal of medicinal chemistry3 citations
Semantic Scholar
Utility of 1,8-diaminonaphthalene in the synthesis of some novel heterocycles as potent anti-MRSA with dual DNA gyrase and topoisomerase IV inhibition
Ebtehal M. Husseiny, N. E. El Menofy, S. El‐Sebaey
2021Egyptian Journal of Chemistry3 citations Open access
Semantic Scholar
Design, synthesis, anticancer estimation, and computational studies of novel benzochromenoimidazopyrimidines as CDK-2 inhibitors and apoptosis stimulators
Fatma G. Abdulrahman, M. Sarg, Yasmin S. Sheta, E. S. Nossier +1 more
2026Molecular diversity2 citations
Semantic Scholar
1,2,3-Triazole-Based Hybrids as EGFR Inhibitors: An overview
Asmaa S. A. Yassen, Nareman A. Nawareg, Ebtehal M. Husseiny, Magda A A El-Sayed +1 more
2025Records of Pharmaceutical and Biomedical Sciences2 citations Open access
Semantic Scholar
1,8-Diaminonaphthalene-derived pharmacophore as potent anti-MRSA with dual DNA gyrase and topoisomerase IV inhibition
Ebtehal M. Husseiny, N. E. El Menofy, S. El‐Sebaey
20222 citations
Semantic Scholar
New Imidazothiazine-containing Scaffolds as Promising Anticancer Agents: Design, Synthesis, and Antiproliferative Estimation
Yasmin S. Sheta, M. Sarg, Fatma G. Abdulrahman, Ebtehal M. Husseiny
2025Azhar International Journal of Pharmaceutical and Medical Sciences1 citations
Semantic Scholar
Design, synthesis, antitumor estimation, and molecular docking of new imidazothiazolediones as potential dual EGFR and IDO1 inhibitors and apoptosis stimulators.
M. Sarg, Fatma G. Abdulrahman, Yasmin S. Sheta, E. S. Nossier +1 more
2026Bioorganic & Medicinal Chemistry0 citations
Semantic Scholar

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Hamada S. Abulkhair×10
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Hamada S. Abulkhair — researcher profile on SciRah
Fatma G. Abdulrahman×8
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Fatma G. Abdulrahman — researcher profile on SciRah
K. E. Anwer×6
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K. E. Anwer — researcher profile on SciRah
M. Sarg×6
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M. Sarg — researcher profile on SciRah

Yasmin S. Sheta

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E. S. Nossier×5

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N. Altwaijry×5

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S. El‐Sebaey×4

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E. M. Othman×3

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E. Fayed — researcher profile on SciRah

Nehad M. El-Dydamony×3

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Adel H. Ghiaty×2

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