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L. Nobre · SciRah

Researcher profile · Semantic Scholar

L. Nobre

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L. Nobre — researcher profile on SciRah

h-index: 16
Works: 101
Citations: 1,489

Most-cited papers

Integrated molecular and clinical analysis of 1,000 pediatric low-grade gliomas
S. Ryall, M. Zápotocký, K. Fukuoka, L. Nobre +41 more
2020Cancer Cell400 citations Open access
Semantic Scholar
Alterations in ALK/ROS1/NTRK/MET drive a group of infantile hemispheric gliomas
A. Guerreiro Stücklin, S. Ryall, K. Fukuoka, M. Zápotocký +58 more
2019Nature Communications299 citations Open access
Semantic Scholar
Genomic predictors of response to PD-1 inhibition in children with germline DNA replication repair deficiency
Anirban Das, S. Sudhaman, D. Morgenstern, Ailish C. Coblentz +79 more
2022Nature Medicine129 citations Open access
Semantic Scholar
Outcomes of BRAF V600E Pediatric Gliomas Treated With Targeted BRAF Inhibition.
L. Nobre, M. Zápotocký, V. Ramaswamy, S. Ryall +69 more
2020JCO Precision Oncology120 citations Open access
Semantic Scholar
Survival and functional outcomes of molecularly defined childhood posterior fossa ependymoma: Cure at a cost
M. Zápotocký, Kiran G Beera, J. Adamski, N. Laperierre +14 more
2019Cancer57 citations Open access
Semantic Scholar
Molecular correlates of cerebellar mutism syndrome in medulloblastoma.
Rashad Jabarkheel, N. Amayiri, Derek W. Yecies, Yuhao (Danny) Huang +23 more
2019Neuro-Oncology44 citations Open access
Semantic Scholar
Immuno-oncologic profiling of pediatric brain tumors reveals major clinical significance of the tumor immune microenvironment
Adrian B. Levine, L. Nobre, Anirban Das, Scott Milos +16 more
2024Nature Communications43 citations Open access
Semantic Scholar
Combined Immunotherapy Improves Outcome for Replication-Repair-Deficient (RRD) High-Grade Glioma Failing Anti–PD-1 Monotherapy: A Report from the International RRD Consortium
Anirban Das, Nick Fernandez, A. Levine, V. Bianchi +59 more
2023Cancer Discovery41 citations Open access
Semantic Scholar
Mutations in the RAS/MAPK Pathway Drive Replication Repair–Deficient Hypermutated Tumors and Confer Sensitivity to MEK Inhibition
B. Campbell, M. Galati, S. Stone, Alexandra N Riemenschneider +25 more
2021Cancer Discovery31 citations Open access
Semantic Scholar
Pattern of Relapse and Treatment Response in WNT-Activated Medulloblastoma
L. Nobre, M. Zápotocký, Sara Khan, K. Fukuoka +57 more
2020Cell Reports Medicine31 citations Open access
Semantic Scholar
Clinical impact of combined epigenetic and molecular analysis of pediatric low grade gliomas.
K. Fukuoka, Yasin Mamatjan, R. Tatevossian, M. Zápotocký +28 more
2020Neuro-Oncology31 citations Open access
Semantic Scholar
The landscape of primary mismatch repair deficient gliomas in children, adolescents, and young adults: a multi-cohort study.
L. Negm, J. Chung, L. Nobre, Julie Bennett +48 more
2024The Lancet Oncology28 citations Open access
Semantic Scholar
Immunohistochemical and nanoString-Based Subgrouping of Clinical Medulloblastoma Samples.
C. D'Arcy, L. Nobre, A. Arnaldo, V. Ramaswamy +3 more
2020Journal of Neuropathology and Experimental Neurology28 citations Open access
Semantic Scholar
Re-irradiation for children with recurrent medulloblastoma in Toronto, Canada: a 20-year experience
D. Tsang, N. Sarhan, V. Ramaswamy, L. Nobre +9 more
2019Journal of Neuro-Oncology22 citations
Semantic Scholar
Brain Tumor Imaging in Adolescents and Young Adults: 2021 WHO Updates for Molecular-based Tumor Types.
M. Wagner, Pejman Jabehdar Maralani, J. Bennett, L. Nobre +7 more
2024Radiology18 citations
Semantic Scholar
Increased confidence of radiomics facilitating pretherapeutic differentiation of BRAF-altered pediatric low-grade glioma
K. Kudus, M. Wagner, K. Namdar, L. Nobre +6 more
2023European Radiology17 citations
Semantic Scholar
A population-based analysis of the molecular landscape of glioma in adolescents and young adults reveals insights into gliomagenesis
Julie Bennett, Adrian B. Levine, L. Nobre, L. Negm +36 more
2025Nature Cancer15 citations
Semantic Scholar
Canadian Consensus for Treatment of BRAF V600E Mutated Pediatric and AYA Gliomas
C. Erker, M. Vanan, V. Larouche, L. Nobre +24 more
2024Current Oncology13 citations Open access
Semantic Scholar
High detection rate of circulating-tumor DNA from cerebrospinal fluid of children with central nervous system germ cell tumors
Yoshiko Nakano, Ian Burns, L. Nobre, R. Siddaway +21 more
2024Acta Neuropathologica Communications12 citations Open access
Semantic Scholar
Effective and safe tumor inhibition using vinblastine in medulloblastoma
L. Nobre, D. Pauck, B. Golbourn, Mara Maue +3 more
2019Pediatric Blood & Cancer12 citations
Semantic Scholar
Clinical and molecular characterization of a multi-institutional cohort of pediatric spinal cord low-grade gliomas
S. Grob, L. Nobre, Kristen Campbell, K. Davies +16 more
2020Neuro-Oncology Advances10 citations Open access
Semantic Scholar
T2-FLAIR Mismatch Sign in Pediatric Low-Grade Glioma
M. Wagner, L. Nobre, K. Namdar, F. Khalvati +3 more
2023American Journal of Neuroradiology8 citations Open access
Semantic Scholar
Treatment response of CNS high‐grade neuroepithelial tumors with MN1 alteration
Lorena V. Baroni, C. Rugilo, F. Lubieniecki, C. Sampor +15 more
2020Pediatric Blood & Cancer8 citations Open access
Semantic Scholar
Beyond hand-crafted features for pretherapeutic molecular status identification of pediatric low-grade gliomas
K. Kudus, M. Wagner, Khashayar Namdar, Julie Bennett +5 more
2024Scientific Reports7 citations Open access
Semantic Scholar
Patterns of hypermutation shape tumorigenesis and immunotherapy response in mismatch-repair-deficient glioma
Nick Fernandez, Yuan Chang, N. Nunes, J. Dimayacyac +31 more
2025Nature Genetics6 citations
Semantic Scholar
Complications following resection of primary and recurrent pediatric posterior fossa ependymoma.
A. Malhotra, L. Nobre, George M. Ibrahim, Abhaya V. Kulkarni +6 more
2024Journal of Neurosurgery: Pediatrics6 citations
Semantic Scholar
Outcomes following management of relapsed pediatric posterior fossa ependymoma in the molecular era
A. Malhotra, L. Nobre, George M. Ibrahim, A. Kulkarni +8 more
2023Journal of Neuro-Oncology5 citations
Semantic Scholar
Liquid biopsy for pediatric brain tumor patients: is it prime time yet?
L. Nobre, C. Hawkins
2022Neuro-Oncology5 citations Open access
Semantic Scholar
Genomics in pediatric high-grade gliomas: Hope or hype practical implications for resource limited settings
Anirban Das, L. Nobre
2023Pediatric Hematology Oncology Journal4 citations Open access
Semantic Scholar
THE CLINICAL AND MOLECULAR LANDSCAPE OF GLIOMAS IN ADOLESCENTS AND YOUNG ADULTS
J. Bennett, L. Nobre, J. Sheth, S. Ryall +27 more
2023Neuro-Oncology Advances4 citations Open access
Semantic Scholar
Indolent course of brainstem tumors with K27M‐H3.3 mutation
Lorena V. Baroni, P. Solano-Páez, L. Nobre, O. Michaeli +5 more
2019Pediatric Blood & Cancer4 citations
Semantic Scholar
ACQUIRED PTEN LOSS MAY MEDIATE DABRAFENIB AND TRAMETINIB RESISTANCE IN BRAF V600E–MUTATED EPITHELIOID GLIOBLASTOMA: A CASE REPORT
Abrar Ahmed, L. Nobre, W. Mason, J. Bennett +3 more
2023Neuro-Oncology Advances3 citations Open access
Semantic Scholar
MODL-47. A NEW MOUSE MODEL OF IDH MUTATED GLIOMAS IDENTIFIES TUMOR CELLS OF ORIGIN AND DETERMINANTS OF SENSITIVITY TO IDH INHIBITORS
Eric Laugesen, Ruxiao Tian, Annette Wu, S. El Ghamrasni +11 more
2023Neuro-Oncology3 citations Open access
Semantic Scholar
BRAF inhibitors in BRAFV600E mutated pediatric high-grade gliomas: upfront or at recurrence?
L. Nobre, E. Bouffet
2022Neuro-Oncology3 citations Open access
Semantic Scholar
Clinical and economic impact of molecular testing for BRAF fusion in pediatric low-grade Glioma
J. D. Rios, Russanthy Velummailum, J. Bennett, L. Nobre +6 more
2022BMC Pediatrics3 citations Open access
Semantic Scholar
Salvage chemotherapy after failure of targeted therapy in a child with BRAF V600E low‐grade glioma
Musthafa Raswoli, L. Nobre, C. Hawkins, U. Bartels +2 more
2020Pediatric Blood & Cancer3 citations Open access
Semantic Scholar
Integrated clinical and molecular landscape of disseminated pediatric low-grade glioma.
Adrian B. Levine, J. Bennett, Prabhumallikarjun Patil, Ian Burns +69 more
2025Neuro-Oncology2 citations Open access
Semantic Scholar
LGG-34. THE LANDSCAPE OF GLIOMAS IN CHILDREN, ADOLESCENTS AND YOUNG ADULTS REVEALS INSIGHTS ON GLIOMAGENESIS: A CANADIAN ADOLESCENTS AND YOUNG ADULTS NEURO-ONCOLOGY NETWORK (CANON) STUDY
J. Bennett, A. Levine, L. Nobre, L. Negm +36 more
2024Neuro-Oncology2 citations Open access
Semantic Scholar
The Clinical Utility of a Tiered Approach to Pediatric Glioma Molecular Characterization for Resource-Limited Settings
Rawan Hammad, L. Nobre, S. Ryall, A. Arnoldo +4 more
2024JCO Global Oncology2 citations Open access
Semantic Scholar
BIOM-12. LIQUID BIOPSIES IN CNS TUMORS: A COMBINED APPROACH TO PROFILING CSF
L. Nobre, Yoshiko Nakano, Ian Burns, Monique Johnson +19 more
2024Neuro-Oncology2 citations Open access
Semantic Scholar
IMMU-17. Comprehensive immunological gene expression profiling of pediatric brain tumors
A. Levine, L. Nobre, Scott Milos, Monique Johnson +5 more
2022Neuro-Oncology2 citations Open access
Semantic Scholar
Mutation and Microsatellite Burden Predict Response to PD-1 Inhibition in Children with Germline DNA Replication Repair Deficiency
U. Tabori, D. Morgenstern, S. Sudhaman, Anirban Das +70 more
20212 citations Open access
Semantic Scholar
High-dose chemotherapy and craniospinal irradiation-sparing approach for WNT medulloblastoma of early childhood
L. Nobre, Vijay Ramaswamy, Christina Coleman, G. Dhall +5 more
2026Journal of Neuro-Oncology1 citations
Semantic Scholar
ID #276 Long-term medical and psychosocial outcomes of a population-based, molecularly characterized pediatric low-grade glioma survivor cohort
Z. Ante, A. Babujee, Ning Liu, J. Mcmahon +15 more
2026Neuro-Oncology Pediatrics1 citations Open access
Semantic Scholar
Tumor-derived cell-free DNA detected in cerebrospinal fluid enables minimally invasive profiling of pediatric brain tumors
L. Nobre, Yoshiko Nakano, Ian Burns, R. Siddaway +30 more
2026Journal of Clinical Investigation1 citations Open access
Semantic Scholar
Cost-effectiveness of dabrafenib plus trametinib in BRAFV600E-mutant pediatric low-grade glioma: A microsimulation study.
Bryan Gascon, Alan Yang, Cindy Gauvreau, Julie Bennett +5 more
2024Journal of Clinical Oncology1 citations
Semantic Scholar
Stalking the stalk: Isolated pituitary stalk thickening and predictive factors for proliferative disease
Julie Bennett, L. Nobre, É. Bouffet, O. Abla +6 more
2024Neuro-Oncology Advances1 citations
Semantic Scholar
Acquired PTEN Loss May Mediate Dabrafenib and Trametinib Resistance in BRAF V600E-Mutated Epithelioid Glioblastoma: A Case Report and Literature Review
Abrar Ahmed, L. Nobre, W. Mason, J. Bennett +3 more
2023EMJ Oncology1 citations Open access
Semantic Scholar
PATH-09. THE IMPACT OF MISMATCH REPAIR DEFICIENCY ON GLIOMAS IN CHILDREN, ADOLESCENTS, AND YOUNG ADULTS; A MULTI-CENTRIC, COLLABORATIVE STUDY LED BY THE IRRDC AND GLIOMA TASKFORCE
L. Negm, J. Chung, L. Nobre, Julie Bennett +23 more
2023Neuro-Oncology1 citations Open access
Semantic Scholar
HGG-27. THE IMPACT OF MISMATCH REPAIR DEFICIENCY ON GLIOMAS IN CHILDREN, ADOLESCENTS, AND YOUNG ADULTS; A REPORT FROM THE IRRDC AND THE GLIOMA TASK FORCE
L. Negm, L. Nobre, J. Bennett, J. Chung +21 more
2023Neuro-Oncology1 citations Open access
Semantic Scholar

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