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G. Thomas · SciRah

Researcher profile · Semantic Scholar

G. Thomas

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G. Thomas — researcher profile on SciRah

h-index: 48
Works: 126
Citations: 18K

Most-cited papers

Oncogenic Signaling Pathways in The Cancer Genome Atlas
F. Sánchez-Vega, M. Mina, J. Armenia, W. Chatila +496 more
2018Cell2,752 citations Open access
Semantic Scholar
Comprehensive Characterization of Cancer Driver Genes and Mutations
M. Bailey, C. Tokheim, E. Porta-Pardo, Sohini Sengupta +496 more
2018Cell2,066 citations Open access
Semantic Scholar
Comprehensive Molecular Characterization of Papillary Renal Cell Carcinoma
W. Linehan, P. Spellman, C. Ricketts, C. Creighton +224 more
2015New England Journal of Medicine1,168 citations Open access
Semantic Scholar
The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma
C. Ricketts, A. D. de Cubas, Huihui Fan, Christof C. Smith +41 more
2018Cell Reports763 citations Open access
Semantic Scholar
Clinical and Genomic Characterization of Treatment-Emergent Small-Cell Neuroendocrine Prostate Cancer: A Multi-institutional Prospective Study.
R. Aggarwal, Jiao-Ti Huang, J. Alumkal, Li Zhang +27 more
2018Journal of Clinical Oncology686 citations Open access
Semantic Scholar
Genomic Hallmarks and Structural Variation in Metastatic Prostate Cancer.
D. Quigley, H. Dang, Shuang G. Zhao, P. Lloyd +59 more
2018Cell658 citations Open access
Semantic Scholar
The Human Tumor Atlas Network: Charting Tumor Transitions across Space and Time at Single-Cell Resolution
O. Rozenblatt-Rosen, A. Regev, Philipp Oberdoerffer, T. Nawy +362 more
2020Cell514 citations Open access
Semantic Scholar
Androgen Receptor Gene Aberrations in Circulating Cell-Free DNA: Biomarkers of Therapeutic Resistance in Castration-Resistant Prostate Cancer
A. Azad, S. Volik, A. Wyatt, A. Haegert +14 more
2015Clinical Cancer Research435 citations Open access
Semantic Scholar
Concordance of Circulating Tumor DNA and Matched Metastatic Tissue Biopsy in Prostate Cancer
A. Wyatt, Matti Annala, R. Aggarwal, K. Beja +15 more
2017Journal of the National Cancer Institute390 citations Open access
Semantic Scholar
Androgen receptor activity in T cells limits checkpoint blockade efficacy
Xiangnan Guan, Fanny Polesso, Chaojie Wang, A. Sehrawat +11 more
2022Nature351 citations Open access
Semantic Scholar
Early evidence of anti-PD-1 activity in enzalutamide-resistant prostate cancer
J. Graff, J. Alumkal, C. Drake, G. Thomas +7 more
2016OncoTarget346 citations Open access
Semantic Scholar
Molecular Characterization and Clinical Relevance of Metabolic Expression Subtypes in Human Cancers
Xin-Xin Peng, Zhong-Yuan Chen, F. Farshidfar, Xiao-Yan Xu +17 more
2018Cell Reports273 citations Open access
Semantic Scholar
Analysis of circulating cell-free DNA identifies multi-clonal heterogeneity of BRCA2 reversion mutations associated with resistance to PARP inhibitors
D. Quigley, J. Alumkal, A. Wyatt, V. Kothari +21 more
2017Cancer Discovery244 citations Open access
Semantic Scholar
Animal models of human prostate cancer: The Consensus Report of the New York Meeting of the Mouse Models of Human Cancers Consortium Prostate Pathology Committee
M. Ittmann, Jiao-Ti Huang, E. Radaelli, P. Martin +10 more
2013Cancer Research231 citations Open access
Semantic Scholar
DNA methylation landscapes in advanced prostate cancer
Shuang G. Zhao, William S. Chen, Hao-Long Li, A. Foye +65 more
2020Nature Genetics228 citations Open access
Semantic Scholar
LSD1 activates a lethal prostate cancer gene network independently of its demethylase function
A. Sehrawat, Li-Na Gao, Yu-Liang Wang, A. Bankhead +20 more
2018Proceedings of the National Academy of Sciences of the United States of America210 citations Open access
Semantic Scholar
The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma.
C. Ricketts, A. D. de Cubas, Huihui Fan, Christof C. Smith +41 more
2018Cell Reports206 citations Open access
Semantic Scholar
Stromal Derived Factor-1 (SDF-1/CXCL12) and CXCR4 in renal cell carcinoma metastasis
Judong Pan, Javier Mestas, M. Burdick, R. Phillips +4 more
2006Molecular Cancer194 citations Open access
Semantic Scholar
Biomarker-Driven Early Clinical Trials in Oncology: A Paradigm Shift in Drug Development
D. Tan, G. Thomas, M. Garrett, U. Banerji +3 more
2009Cancer Journal172 citations
Semantic Scholar
HIF1α Protein Stability Is Increased by Acetylation at Lysine 709*
Hao Geng, Qiong Liu, C. Xue, L. David +4 more
2012Journal of Biological Chemistry149 citations Open access
Semantic Scholar
Transcriptional profiling identifies an androgen receptor activity-low, stemness program associated with enzalutamide resistance
J. Alumkal, Duan-Chen Sun, Eric Lu, T. Beer +27 more
2020Proceedings of the National Academy of Sciences of the United States of America127 citations Open access
Semantic Scholar
Genomic Drivers of Poor Prognosis and Enzalutamide Resistance in Metastatic Castration-resistant Prostate Cancer
William S. Chen, R. Aggarwal, Li Zhang, Shuang G. Zhao +24 more
2019European Urology119 citations Open access
Semantic Scholar
A phase II single-arm study of pembrolizumab with enzalutamide in men with metastatic castration-resistant prostate cancer progressing on enzalutamide alone
J. Graff, T. Beer, J. Alumkal, Rachel Slottke +10 more
2020Journal for ImmunoTherapy of Cancer117 citations Open access
Semantic Scholar
MEK-ERK signaling is a therapeutic target in metastatic castration resistant prostate cancer
N. Nickols, R. Nazarian, Shuang G. Zhao, Victor M. Tan +27 more
2019Prostate Cancer and Prostatic Diseases88 citations Open access
Semantic Scholar
Presence of tumor necrosis is not a significant predictor of survival in clear cell renal cell carcinoma: higher prognostic accuracy of extent based rather than presence/absence classification.
T. Klatte, J. Said, M. De Martino, J. Larochelle +6 more
2009Journal of Urology87 citations
Semantic Scholar
Metabolic reprogramming ensures cancer cell survival despite oncogenic signaling blockade
Hui-wen Lue, J. Podolak, Kevin S. Kolahi, Larry C. Cheng +18 more
2017Genes & Development82 citations Open access
Semantic Scholar
Can molecular biomarker-based patient selection in Phase I trials accelerate anticancer drug development?
C. Carden, D. Sarker, S. Postel-Vinay, T. Yap +7 more
2010Drug Discovery Today77 citations
Semantic Scholar
Systemic Inhibition of CREB is Well-tolerated in vivo
Bing-Bing X. Li, R. Gardner, C. Xue, David Z. Qian +5 more
2016Scientific Reports74 citations Open access
Semantic Scholar
Sulforaphane Bioavailability and Chemopreventive Activity in Men Presenting for Biopsy of the Prostate Gland: A Randomized Controlled Trial
Zhenzhen Zhang, M. Garzotto, E. Davis, M. Mori +10 more
2019Nutrition and Cancer71 citations Open access
Semantic Scholar
Characterization of neuroendocrine prostate cancer (NEPC) in patients with metastatic castration resistant prostate cancer (mCRPC) resistant to abiraterone (Abi) or enzalutamide (Enz): Preliminary results from the SU2C/PCF/AACR West Coast Prostate Cancer Dream Team (WCDT).
E. Small, Jiao-Ti Huang, J. Youngren, A. Sokolov +16 more
201566 citations
Semantic Scholar
A HIF-regulated VHL-PTP1B-Src signaling axis identifies a therapeutic target in Renal Cell Carcinoma
N. Suwaki, Elsa Vanhecke, K. Atkins, M. Graf +21 more
2011Science Translational Medicine66 citations Open access
Semantic Scholar
Proteome Profiling of 1 to 5 Spiked Circulating Tumor Cells Isolated from Whole Blood Using Immunodensity Enrichment, Laser Capture Microdissection, Nanodroplet Sample Processing, and Ultrasensitive nanoLC-MS
Ying Zhu, J. Podolak, Rui Zhao, Anil K. Shukla +3 more
2018Analytical Chemistry65 citations Open access
Semantic Scholar
Whole Genome and Transcriptional Analysis of Treatment-Emergent Small Cell Neuroendocrine Prostate Cancer Demonstrates Intra-class Heterogeneity
R. Aggarwal, D. Quigley, Jiao-Ti Huang, Li Zhang +14 more
2019Molecular Cancer Research64 citations Open access
Semantic Scholar
Wilms' Tumor Protein Induces an Epithelial-Mesenchymal Hybrid Differentiation State in Clear Cell Renal Cell Carcinoma
Valerie B. Sampson, J. David, I. Puig, Pratima U. Patil +3 more
2014PLoS ONE64 citations Open access
Semantic Scholar
Transcriptional profiling of matched patient biopsies clarifies molecular determinants of enzalutamide-induced lineage plasticity
T. Westbrook, Xiangnan Guan, E. Rodansky, D. Flores +33 more
2022Nature Communications55 citations Open access
Semantic Scholar
The 5-Hydroxymethylcytosine Landscape of Prostate Cancer
Martin Sjöström, S. Zhao, S. Levy, Meng Zhang +60 more
2022Cancer Research55 citations Open access
Semantic Scholar
Characterizing advanced breast cancer heterogeneity and treatment resistance through serial biopsies and comprehensive analytics
Allen Li, Jamie M. Keck, Swapnil Parmar, J. Patterson +14 more
2021npj Precision Oncology43 citations Open access
Semantic Scholar
Oncogenic MYC Induces the Impaired Ribosome Biogenesis Checkpoint and Stabilizes p53, Independent of Increased Ribosome Content.
Carmen Morcelle, Sandra Menoyo, Francisco D. Morón-Duran, A. Tauler +3 more
2019Cancer Research40 citations Open access
Semantic Scholar
CT-Guided Bone Biopsies in Metastatic Castration-Resistant Prostate Cancer: Factors Predictive of Maximum Tumor Yield.
Michael G Holmes, E. Foss, G. Joseph, A. Foye +10 more
2017Journal of Vascular and Interventional Radiology36 citations Open access
Semantic Scholar
Multi-Omics Analyses Detail Metabolic Reprogramming in Lipids, Carnitines, and Use of Glycolytic Intermediates between Prostate Small Cell Neuroendocrine Carcinoma and Prostate Adenocarcinoma
Bei Gao, Hui-wen Lue, J. Podolak, S. Fan +5 more
2019Metabolites35 citations Open access
Semantic Scholar
Pembrolizumab (Pembro) plus enzalutamide (Enz) in metastatic castration resistant prostate cancer (mCRPC): Extended follow up.
J. Graff, J. Alumkal, Reid F. Thompson, Amy E. Moran +5 more
201835 citations
Semantic Scholar
First evidence of significant clinical activity of PD-1 inhibitors in metastatic, castration resistant prostate cancer (mCRPC)
J. Graff, J. Alumkal, C. Drake, G. Thomas +4 more
201630 citations Open access
Semantic Scholar
An Omic and Multidimensional Spatial Atlas from Serial Biopsies of an Evolving Metastatic Breast Cancer
Brett E. Johnson, Allison L. Creason, J. Stommel, Jamie M. Keck +39 more
2020bioRxiv26 citations Open access
Semantic Scholar
Serum cholesterol levels and tumor growth in a PTEN-null transgenic mouse model of prostate cancer
E. Allott, E. Masko, Alexis R. Freedland, Everardo Macias +7 more
2018Prostate Cancer and Prostatic Diseases26 citations Open access
Semantic Scholar
Epigenetic loss of heterogeneity from low to high grade localized prostate tumours
S. Eksi, Alex Chitsazan, Zeynep Sayar, G. Thomas +4 more
2021Nature Communications25 citations Open access
Semantic Scholar
Androgen receptor amplification is concordant between circulating tumor cells and biopsies from men undergoing treatment for metastatic castration resistant prostate cancer
J. Podolak, K. Eilers, Timothy A. Newby, Rachel Slottke +10 more
2017OncoTarget24 citations Open access
Semantic Scholar
Tissue-Based Research in Kidney Cancer: Current Challenges and Future Directions
S. Signoretti, G. Bratslavsky, F. Waldman, V. Reuter +11 more
2008Clinical Cancer Research23 citations Open access
Semantic Scholar
Impact of carbohydrate restriction in the context of obesity on prostate tumor growth in the Hi-Myc transgenic mouse model
E. Allott, Everardo Macias, Sergio E. Sanders, Beatrice S. Knudsen +3 more
2017Prostate Cancer and Prostatic Diseases21 citations Open access
Semantic Scholar
Double autophagy stimulation using chemotherapy and mTOR inhibition combined with hydroxychloroquine for autophagy modulation in patients with relapsed or refractory multiple myeloma
E. Scott, R. Maziarz, S. Spurgeon, E. Medvedova +13 more
2017Haematologica21 citations Open access
Semantic Scholar
Genetic Profiling to Determine Risk of Relapse Free Survival in High-risk Localized Prostate Cancer
Christine M. Barnett, M. Heinrich, J. Lim, D. Nelson +9 more
2013Clinical Cancer Research21 citations Open access
Semantic Scholar

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