Olga Familiar

Most-cited papers

1. Exploring Acyclic Nucleoside Analogues as Inhibitors of Mycobacterium tuberculosis Thymidylate Kinase

   Olga Familiar, H. Munier-Lehmann, A. Negri, F. Gago +5 more

   2008ChemMedChem38 citations

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2. Design, synthesis and inhibitory activity against Mycobacterium tuberculosis thymidine monophosphate kinase of acyclic nucleoside analogues with a distal imidazoquinolinone.

   Olga Familiar, H. Munier-Lehmann, J. Aínsa, M. Camarasa +1 more

   2010European journal of medicinal chemistry36 citations Open access

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3. Structure, physiological role, and specific inhibitors of human thymidine kinase 2 (TK2): Present and future

   M. Pérez-Pérez, Eva-María Priego, Ana-Isabel Hernández, Olga Familiar +4 more

   2008Medicinal research reviews (Print)30 citations Open access

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4. From β‐Amino‐γ‐sultone to Unusual Bicyclic Pyridine and Pyrazine Heterocyclic Systems: Synthesis and Cytostatic and Antiviral Activities

   S. de Castro, Olga Familiar, G. Andrei, R. Snoeck +3 more

   2011ChemMedChem24 citations

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5. N1-substituted thymine derivatives as mitochondrial thymidine kinase (TK-2) inhibitors.

   Ana-Isabel Hernández, Olga Familiar, A. Negri, Fátima Rodríguez-Barrios +5 more

   2006Journal of Medicinal Chemistry16 citations Open access

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6. Cationic Pd II Complexes of Fesulphos Ligands: Highly Efficient Catalysts for the Enantioselective Ring Opening of Oxa- and Azabicyclic Alkenes with Dialkylzinc Reagents

   S. Cabrera, Inés Alonso, R. G. Arrayás, Olga Familiar +1 more

   20053 citations

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7. Design, Synthesis and Inhibitory Activity Against Mycobacterium tuberculosis Thymidine Monophosphate Kinase of Acyclic Nucleoside Analogues with a Distal Imidazoquinolinone.

   Olga Familiar, Hélène Munier-Lehmann, J. Aínsa, M. Camarasa +1 more

   20111 citations

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8. Unexpected similarities between a human and a mycobacterial enzyme that catalyze a different reaction

   A. Negri, Olga Familiar, J. Balzarini, H. Munier-Lehmann +3 more

   20071 citations

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9. Mitochondrial thymidine kinase (TK-2) inhibitors: an overview on their chemistry, enzyme kinetics and a proposed model of interaction with TK-2

   M. Pérez-Pérez, Olga Familiar, Leire Aguado, Eva-María Priego +5 more

   20070 citations

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10. Cationic PdII Complexes of Fesulphos Ligands: Highly Efficient Catalysts for the Enantioselective Ring Opening of Oxa‐ and Azabicyclic Alkenes with Dialkylzinc Reagents

    S. Cabrera, Inés Alonso, R. G. Arrayás, Olga Familiar +1 more

    20050 citations

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11. Inhibition of mitochondrial thymidine kinase (TK-2) and related enzymes by N-1-substituted thymine derivatives

    Olga Familiar, Ana-Isabel Hernández, M. Camarasa, J. Balzarini

    20050 citations

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