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M. Ubasawa · SciRah

Researcher profile · Semantic Scholar

M. Ubasawa

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M. Ubasawa — researcher profile on SciRah

h-index: 18
Works: 36
Citations: 1,334

Most-cited papers

Synthesis and antiviral activity of deoxy analogs of 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine (HEPT) as potent and selective anti-HIV-1 agents.
Hiromichi Tanaka, H. Takashima, M. Ubasawa, K. Sekiya +6 more
1992Journal of Medicinal Chemistry147 citations
Semantic Scholar
Potent and selective inhibition of human immunodeficiency virus type 1 (HIV-1) by 5-ethyl-6-phenylthiouracil derivatives through their interaction with the HIV-1 reverse transcriptase.
Masanori Baba, E. De Clercq, H. Tanaka, M. Ubasawa +6 more
1991Proceedings of the National Academy of Sciences of the United States of America143 citations Open access
Semantic Scholar
Structure-activity relationships of 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine analogues: effect of substitutions at the C-6 phenyl ring and at the C-5 position on anti-HIV-1 activity.
Hiromichi Tanaka, H. Takashima, M. Ubasawa, K. Sekiya +6 more
1992Journal of Medicinal Chemistry132 citations
Semantic Scholar
A new class of HIV-1-specific 6-substituted acyclouridine derivatives: synthesis and anti-HIV-1 activity of 5- or 6-substituted analogues of 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine (HEPT).
Hiromichi Tanaka, Masanori Baba, H. Hayakawa, Takashi Sakamaki +9 more
1991Journal of Medicinal Chemistry125 citations
Semantic Scholar
Synthesis of the 3'-terminal decaribonucleoside nonaphosphate of yeast alanine transfer ribonucleic acid
Simon S. Jones, B. Rayner, C. Reese, A. Ubasawa +1 more
1980112 citations
Semantic Scholar
Preclinical evaluation of MKC-442, a highly potent and specific inhibitor of human immunodeficiency virus type 1 in vitro
M. Baba, S. Shigeta, Satoshi Yuasa, H. Takashima +6 more
1994Antimicrobial Agents and Chemotherapy107 citations Open access
Semantic Scholar
Synthesis and anti-HIV activity of 2-, 3-, and 4-substituted analogues of 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine (HEPT).
Hiromichi Tanaka, Masanori Baba, M. Ubasawa, H. Takashima +6 more
1991Journal of Medicinal Chemistry71 citations
Semantic Scholar
Highly potent and selective inhibition of human immunodeficiency virus type 1 by a novel series of 6-substituted acyclouridine derivatives.
M. Baba, E. De Clercq, Hirofumi Tanaka, M. Ubasawa +6 more
1991Molecular Pharmacology69 citations
Semantic Scholar
Specific anti-HIV-1 "acyclonucleosides" which cannot be phosphorylated: synthesis of some deoxy analogues of 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine.
H. Tanaka, M. Baba, S. Saito, T. Miyasaka +6 more
1991Journal of Medicinal Chemistry66 citations
Semantic Scholar
Selective and synergistic inhibition of human immunodeficiency virus type 1 reverse transcriptase by a non-nucleoside inhibitor, MKC-442.
Satoshi Yuasa, Yasuyo Sadakata, H. Takashima, K. Sekiya +3 more
1993Molecular Pharmacology44 citations
Semantic Scholar
Synthesis and antiviral activity of 6-benzyl analogs of 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine (HEPT) as potent and selective anti-HIV-1 agents.
Hirofumi Tanaka, H. Takashima, M. Ubasawa, K. Sekiya +6 more
2010Journal of Medicinal Chemistry42 citations
Semantic Scholar
Highly potent and selective inhibition of HIV-1 replication by 6-phenylthiouracil derivatives.
Masanori Baba, S. Shigeta, Hiromichi Tanaka, T. Miyasaka +5 more
1992Antiviral Research39 citations
Semantic Scholar
Hept Derivatives: 6-Benzyl-1-ethoxymethyl-5-isopropyluracil (MKC-442)
M. Baba, H. Tanaka, T. Miyasaka, Satoshi Yuasa +3 more
199535 citations
Semantic Scholar
2-Amino-6-arylthio-9-[2-(phosphonomethoxy)ethyl]purine bis(2,2,2-trifluoroethyl) esters as novel HBV-specific antiviral reagents.
K. Sekiya, H. Takashima, Naoko Ueda, Naohiro Kamiya +3 more
2002Journal of Medicinal Chemistry29 citations
Semantic Scholar
Antiviral Activities of MCC-478, a Novel and Specific Inhibitor of Hepatitis B Virus
Naohiro Kamiya, A. Kubota, Y. Iwase, K. Sekiya +2 more
2002Antimicrobial Agents and Chemotherapy29 citations Open access
Semantic Scholar
Anti-human immunodeficiency virus type 1 activities and pharmacokinetics of novel 6-substituted acyclouridine derivatives
Masanori Baba, E. De Clercq, S. Iida, H. Tanaka +6 more
1990Antimicrobial Agents and Chemotherapy27 citations Open access
Semantic Scholar
Synergistic inhibition of human immunodeficiency virus type 1 replication by 5-ethyl-1-ethoxymethyl-6-(phenylthio)uracil (E-EPU) and azidothymidine in vitro
Masanori Baba, Masahiko Ito, S. Shigeta, H. Tanaka +5 more
1991Antimicrobial Agents and Chemotherapy24 citations Open access
Semantic Scholar
Synthesis of some analogues of 1-[(2-hydroxyethoxy)-methyl]-6-(phenylthio)thymine (hept) which have different types of acyclic structures
Hiromichi Tanaka, T. Miyasaka, K. Sekiya, H. Takashima +5 more
199218 citations
Semantic Scholar
A Convenient One-Pot Synthesis of Acyclonucleosides.
M. Ubasawa, H. Takashima, K. Sekiya
199516 citations Open access
Semantic Scholar
Lithiation of Uracilnucleosides and its Application to the Synthesis of a New Class of Anti-HIV-1 Acyclonucleosides
Hiromichi Tanaka, M. Baba, H. Hayakawa, K. Haraguchi +7 more
199116 citations
Semantic Scholar
Studies on transfer ribonucleic acids and related compounds. VI. Synthesis of yeast alanine transfer ribonucleic acid 3'-terminal nonanucleotides and 5'-terminal hexanucleotides.
E. Otsuka, M. Ubasawa, S. Morioka, Morio Ikehara
1973Journal of the American Chemical Society11 citations
Semantic Scholar
Synthesis and Anti‐HIV Activity of 2‐, 3‐, and 4‐Substituted Analogues of 1‐((2‐Hydroxyethoxy)methyl)‐6‐(phenylthio)thymine (HEPT).
Hirofumi Tanaka, M. Baba, M. Ubasawa, H. Takashima +6 more
19919 citations
Semantic Scholar
A New Class of HIV‐1‐Specific 6‐Substituted Acyclouridine Derivatives: Synthesis and Anti‐HIV Activity of 5‐ or 6‐Substituted Analogues of 1‐( (2‐Hydroxyethoxy)methyl)‐6‐(phenylthio)thymine (HEPT).
Hirofumi Tanaka, M. Baba, H. Hayakawa, Takashi Sakamaki +9 more
19918 citations
Semantic Scholar
Molecular simulation of 5,6-substituted 1-[(2-hydroxyethoxy)methyl]uracils with anti-HIV-1 activity
P. Mager, E. De Clercq, H. Takashima, M. Ubasawa +3 more
19967 citations
Semantic Scholar
Some Aspects on Acyclonucleoside Synthesis
M. Ubasawa, H. Takashima, Kouichi Sdciya
19985 citations
Semantic Scholar
The synthesis of novel 6-substituted acyclouridine derivatives which show specific inhibition of HIV-1
Hiromichi Tanaka, M. Baba, M. Ubasawa, H. Takashima +5 more
19904 citations
Semantic Scholar
STUDIES ON TRANSFER RIBONUCLEIC ACIDS AND RELATED COMPOUNDS PART 6, SYNTHESIS OF YEAST ALANINE TRANSFER RIBONUCLEIC ACID 3′-TERMINAL NONANUCLEOTIDES AND 5′-TERMINAL HEXANUCLEOTIDES
E. Ohtsuka, M. Ubasawa, S. Morioka, M. Ikehara
19732 citations
Semantic Scholar
Tris(p-tolylsilyl)amine
M. Baba, E. Takahashi, M. Ubasawa, J. Yao
19951 citations
Semantic Scholar
Some Aspects on Acyclonucleoside Synthesis.
M. Ubasawa, H. Takashima, K. Sekiya
19990 citations
Semantic Scholar
HEPT Derivatives: 6-Benzyl-1-ethoxymethyl-5-isopropyluracil (MKC-442).
M. Baba, H. Tanaka, T. Miyasaka, Satoshi Yuasa +3 more
19950 citations
Semantic Scholar
Preclinical Evaluation ofMKC-442, aHighly Potent and Specific Inhibitor ofHumanImmunodeficiency Virus Type1InVitro
M. Ubasawa, M. Kasei
19940 citations
Semantic Scholar
A simple and convenient method for acyclonucleoside synthesis.
M. Ubasawa, H. Takashima, K. Sekiya
1992Nucleic Acids Symposium Series0 citations
Semantic Scholar
Anti-Human Immunodeficiency Virus Type1Activities and Pharmacokinetics ofNovel6-Substituted Acyclouridine Derivatives
M. Ubasawa
19900 citations
Semantic Scholar
Synthesis of novel 6-substituted acyclouridine derivatives and their anti-HIV-1 activity.
H. Tanaka, M. Baba, M. Ubasawa, H. Takashima +5 more
1990Nucleic Acids Symposium Series0 citations
Semantic Scholar
Acyclic 6-substituted pyrimidine nucleoside derivatives and antiviral agents containing the same as active agent.
T. Miyasaka, Hiromichi Tanaka, C. E. De, M. Baba +2 more
19890 citations
Semantic Scholar
SYNTHESIS OF THE 3′-TERMINAL DECARIBONUCLEOSIDE NONAPHOSPHATE OF YEAST ALANINE TRANSFER RIBONUCLEIC ACID
Simon S. Jones, B. Rayner, C. Reese, A. Ubasawa +1 more
19810 citations
Semantic Scholar

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H. Takashima×23
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H. Takashima — researcher profile on SciRah
K. Sekiya×20
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E. De Clercq×16
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I. Nitta×14
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T. Miyasaka — researcher profile on SciRah

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M. Baba — researcher profile on SciRah

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Masanori Baba×10

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S. Shigeta — researcher profile on SciRah

Hiromichi Tanaka×9

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Hiromichi Tanaka — researcher profile on SciRah

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H. Tanaka — researcher profile on SciRah

Richard T. Walker×6

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Richard T. Walker — researcher profile on SciRah