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K. De Ruyck · SciRah

Researcher profile · Semantic Scholar

K. De Ruyck

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K. De Ruyck — researcher profile on SciRah

h-index: 31
Works: 94
Citations: 4,316

Most-cited papers

Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci
F. Schumacher, A. A. Al Olama, S. Berndt, S. Benlloch +183 more
2018Nature Genetics808 citations Open access
Semantic Scholar
Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction
D. Conti, B. Darst, Lilit C. Moss, E. Saunders +227 more
2021Nature Genetics407 citations Open access
Semantic Scholar
Polymorphisms in base-excision repair and nucleotide-excision repair genes in relation to lung cancer risk.
K. De Ruyck, M. Szaumkessel, Isabelle De Rudder, Annelore Dehoorne +5 more
2007Mutation research220 citations
Semantic Scholar
Association analyses identify 31 new risk loci for colorectal cancer susceptibility
P. Law, Maria Timofeeva, C. Fernández-Rozadilla, P. Broderick +155 more
2019Nature Communications205 citations Open access
Semantic Scholar
Predicting esophagitis after chemoradiation therapy for non-small cell lung cancer: an individual patient data meta-analysis.
David A. Palma, Suresh Senan, Cary Oberije, J. Belderbos +12 more
2013International Journal of Radiation Oncology, Biology, Physics184 citations Open access
Semantic Scholar
Large-scale transcriptome-wide association study identifies new prostate cancer risk regions
N. Mancuso, S. Gayther, Alexander Gusev, Wei Zheng +70 more
2018Nature Communications145 citations Open access
Semantic Scholar
Radiation-induced damage to normal tissues after radiotherapy in patients treated for gynecologic tumors: association with single nucleotide polymorphisms in XRCC1, XRCC3, and OGG1 genes and in vitro chromosomal radiosensitivity in lymphocytes.
K. De Ruyck, M. V. van Eijkeren, K. Claes, R. Morthier +4 more
2005International Journal of Radiation Oncology, Biology, Physics141 citations
Semantic Scholar
Characterizing prostate cancer risk through multi-ancestry genome-wide discovery of 187 novel risk variants
Anqi Wang, Jiayi Shen, Alex A. Rodriguez, E. Saunders +309 more
2023Nature Genetics136 citations Open access
Semantic Scholar
Acute normal tissue reactions in head-and-neck cancer patients treated with IMRT: influence of dose and association with genetic polymorphisms in DNA DSB repair genes.
Joke Werbrouck, K. De Ruyck, F. Duprez, L. Veldeman +7 more
2009International Journal of Radiation Oncology, Biology, Physics134 citations
Semantic Scholar
Predicting risk of radiation-induced lung injury.
I. Madani, K. De Ruyck, H. Goeminne, W. De Neve +2 more
2007Journal of Thoracic Oncology129 citations Open access
Semantic Scholar
Factors modifying the risk for developing acute skin toxicity after whole-breast intensity modulated radiotherapy
S. De Langhe, T. Mulliez, L. Veldeman, V. Remouchamps +6 more
2014BMC Cancer126 citations Open access
Semantic Scholar
Individual patient data meta-analysis shows a significant association between the ATM rs1801516 SNP and toxicity after radiotherapy in 5456 breast and prostate cancer patients
C. Andreassen, B. Rosenstein, S. Kerns, H. Ostrer +40 more
2016Radiotherapy and Oncology120 citations Open access
Semantic Scholar
Identification of multiple risk loci and regulatory mechanisms influencing susceptibility to multiple myeloma
M. Went, A. Sud, A. Försti, Britta Halvarsson +127 more
2018Nature Communications108 citations Open access
Semantic Scholar
Fine-mapping of prostate cancer susceptibility loci in a large meta-analysis identifies candidate causal variants
Tokhir Dadaev, E. Saunders, P. Newcombe, Ezequiel Anokian +306 more
2018Nature Communications105 citations Open access
Semantic Scholar
Radiogenomics: Radiobiology Enters the Era of Big Data and Team Science
B. Rosenstein, C. West, S. Bentzen, J. Alsner +34 more
2014International Journal of Radiation Oncology, Biology, Physics105 citations Open access
Semantic Scholar
Shared heritability and functional enrichment across six solid cancers
Xia Jiang, H. Finucane, F. Schumacher, S. Schmit +329 more
2019Nature Communications104 citations Open access
Semantic Scholar
Single-nucleotide polymorphisms in DNA double-strand break repair genes: association with head and neck cancer and interaction with tobacco use and alcohol consumption.
Joke Werbrouck, K. De Ruyck, F. Duprez, M. V. van Eijkeren +5 more
2008Mutation research83 citations
Semantic Scholar
Polymorphisms in nonhomologous end‐joining genes associated with breast cancer risk and chromosomal radiosensitivity
P. Willems, K. Claes, A. Baeyens, V. Vandersickel +9 more
2008Genes, Chromosomes and Cancer74 citations
Semantic Scholar
Polygenic hazard score is associated with prostate cancer in multi-ethnic populations
M. Huynh-Le, Chun-Chieh Fan, R. Karunamuni, W. Thompson +74 more
2020Nature Communications64 citations Open access
Semantic Scholar
TGFbeta1 polymorphisms and late clinical radiosensitivity in patients treated for gynecologic tumors.
K. De Ruyck, M. V. van Eijkeren, K. Claes, K. Bacher +3 more
2006International Journal of Radiation Oncology, Biology, Physics64 citations
Semantic Scholar
Quantification of radiation-induced lung damage with CT scans: The possible benefit for radiogenomics
D. D. De Ruysscher, H. Sharifi, G. Defraene, S. Kerns +7 more
2013Acta oncologica58 citations Open access
Semantic Scholar
Prediction of late normal tissue complications in RT treated gynaecological cancer patients: potential of the gamma-H2AX foci assay and association with chromosomal radiosensitivity.
Joke Werbrouck, K. De Ruyck, L. Beels, A. Vral +3 more
2009Oncology Report57 citations Open access
Semantic Scholar
Cytogenetic biodosimetry of an accidental exposure of a radiological worker using multiple assays.
H. Thierens, K. De Ruyck, A. Vral, V. de Gelder +3 more
2005Radiation Protection Dosimetry53 citations
Semantic Scholar
Genetic variation in three candidate genes and nicotine dependence, withdrawal and smoking cessation in hospitalized patients.
K. De Ruyck, K. Nackaerts, L. Beels, Joke Werbrouck +5 more
2010Pharmacogenomics (London)49 citations
Semantic Scholar
Genome-wide association study of classical Hodgkin lymphoma identifies key regulators of disease susceptibility
A. Sud, H. Thomsen, P. Law, A. Försti +87 more
2017Nature Communications44 citations Open access
Semantic Scholar
Biologic dosimetry of 188Re-HDD/lipiodol versus 131I-lipiodol therapy in patients with hepatocellular carcinoma.
K. De Ruyck, B. Lambert, K. Bacher, F. Gemmel +5 more
2004Journal of Nuclear Medicine43 citations
Semantic Scholar
Integrated models for the prediction of late genitourinary complaints after high-dose intensity modulated radiotherapy for prostate cancer: making informed decisions.
S. De Langhe, G. De Meerleer, K. De Ruyck, P. Ost +3 more
2014Radiotherapy and Oncology39 citations
Semantic Scholar
Factors Associated With Early Mortality in Patients Treated With Concurrent Chemoradiation Therapy for Locally Advanced Non-Small Cell Lung Cancer.
A. Warner, M. Dahele, Bo Hu, D. Palma +13 more
2016International Journal of Radiation Oncology, Biology, Physics37 citations Open access
Semantic Scholar
A polymorphism in the promoter region of Ku70/XRCC6, associated with breast cancer risk and oestrogen exposure
P. Willems, K. De Ruyck, R. Van den Broecke, A. Makar +3 more
2009Journal of Cancer Research and Clinical Oncology37 citations Open access
Semantic Scholar
Genetically proxied glucose-lowering drug target perturbation and risk of cancer: a Mendelian randomisation analysis
J. Yarmolinsky, E. Bouras, Andrei-Emil Constantinescu, K. Burrows +91 more
2023Diabetologia36 citations Open access
Semantic Scholar
Development of a multicomponent prediction model for acute esophagitis in lung cancer patients receiving chemoradiotherapy.
K. De Ruyck, Nick Sabbe, C. Oberije, K. Vandecasteele +6 more
2011International Journal of Radiation Oncology, Biology, Physics36 citations Open access
Semantic Scholar
Circulating Metabolic Biomarkers of Screen-Detected Prostate Cancer in the ProtecT Study
Charleen D. Adams, R. Richmond, D. L. Santos Ferreira, W. Spiller +72 more
2018Cancer Epidemiology, Biomarkers and Prevention33 citations Open access
Semantic Scholar
Genome-wide association study identifies susceptibility loci for B-cell childhood acute lymphoblastic leukemia
J. Vijayakrishnan, J. Studd, P. Broderick, B. Kinnersley +92 more
2018Nature Communications31 citations Open access
Semantic Scholar
Clinical Investigation : Genitourinary Cancer Acute Radiation-Induced Nocturia in Prostate Cancer Patients Is Associated With Pretreatment Symptoms , Radical Prostatectomy , and Genetic Markers in the TGF b 1 Gene
S. De Langhe, K. De Ruyck, P. Ost, V. Fonteyne +4 more
201329 citations
Semantic Scholar
Prostate cancer risk stratification improvement across multiple ancestries with new polygenic hazard score
M. Huynh-Le, R. Karunamuni, Chun-Chieh Fan, Lui Asona +71 more
2022Prostate Cancer and Prostatic Diseases28 citations Open access
Semantic Scholar
Effect of the rs1051730-rs16969968 variant and smoking cessation treatment: a meta-analysis.
Tiffany Leung, A. Bergen, M. Munafo, K. De Ruyck +2 more
2015Pharmacogenomics (London)28 citations
Semantic Scholar
A let-7 microRNA polymorphism in the KRAS 3'-UTR is prognostic in oropharyngeal cancer.
K. De Ruyck, F. Duprez, Liesbeth Ferdinande, Chamberlain Mbah +10 more
2014Cancer Epidemiology28 citations Open access
Semantic Scholar
Microsatellite Polymorphisms in DNA Repair Genes XRCC1, XRCC3 and XRCC5 in Patients with Gynecological Tumors: Association with Late Clinical Radiosensitivity and Cancer Incidence
K. De Ruyck, C. Wilding, M. V. van Eijkeren, R. Morthier +2 more
2005Radiation Research28 citations Open access
Semantic Scholar
Chromosomal radiosensitivity in head and neck cancer patients: evidence for genetic predisposition?
K. De Ruyck, V. de Gelder, M. V. van Eijkeren, T. Boterberg +3 more
2008British Journal of Cancer27 citations Open access
Semantic Scholar
No association between TGF-β1 polymorphisms and radiation-induced lung toxicity in a European cohort of lung cancer patients.
A. Voets, C. Oberije, Robin B Struijk, B. Reymen +8 more
2012Radiotherapy and Oncology26 citations Open access
Semantic Scholar
The CHEK2 Variant C.349A>G Is Associated with Prostate Cancer Risk and Carriers Share a Common Ancestor
Andreia Brandão, P. Paulo, S. Maia, M. Pinheiro +57 more
2020Cancers22 citations Open access
Semantic Scholar
Epigenetic changes in lymphocytes of solvent-exposed individuals.
L. Godderis, K. Deraedt, Ali M. Tabish, K. Poels +5 more
2012Epigenomics21 citations Open access
Semantic Scholar
Evaluating approaches for constructing polygenic risk scores for prostate cancer in men of African and European ancestry.
B. Darst, Jiayi Shen, R. Madduri, Alexis A. Rodriguez +104 more
2023American Journal of Human Genetics20 citations Open access
Semantic Scholar
Effect of changes in lipid classes during wilting and ensiling of red clover using two silage additives on in vitro ruminal biohydrogenation
F. Gadeyne, K. De Ruyck, G. Van Ranst, N. De Neve +2 more
2016Journal of Agricultural Sciences20 citations
Semantic Scholar
Use of Angiotensin Converting Enzyme Inhibitors is Associated with Reduced Risk of Late Bladder Toxicity Following Radiotherapy for Prostate Cancer
S. Kerns, Ashley Amidon Morlang, Sharon Lee, Derick R. Peterson +42 more
2022Radiotherapy and Oncology19 citations Open access
Semantic Scholar
Germline variation at 8q24 and prostate cancer risk in men of European ancestry
M. Matejcic, E. Saunders, Tokhir Dadaev, M. Brook +300 more
2018Nature Communications19 citations Open access
Semantic Scholar
Large-scale meta–genome-wide association study reveals common genetic factors linked to radiation-induced acute toxicities across cancer types
E. Naderi, Miguel E. Aguado-Barrera, L. M. Schack, L. Dorling +80 more
2023JNCI Cancer Spectrum17 citations Open access
Semantic Scholar
Author Correction: Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci
F. Schumacher, Ali Olama, S. Berndt, S. Benlloch +183 more
2019Nature Genetics17 citations Open access
Semantic Scholar
mBAND analysis of chromosome aberrations in lymphocytes exposed in vitro to α-particles and γ-rays
E. Tawn, C. Whitehouse, D. Holdsworth, K. De Ruyck +2 more
2008International Journal of Radiation Biology16 citations
Semantic Scholar
Chromosomal radiosensitivity of breast cancer with a CHEK2 mutation.
A. Baeyens, K. Claes, P. Willems, K. De Ruyck +2 more
2005Cancer Genetics and Cytogenetics16 citations
Semantic Scholar

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