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Nelson E. Brown · SciRah

Researcher profile · Semantic Scholar

Nelson E. Brown

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Nelson E. Brown — researcher profile on SciRah

h-index: 16
Works: 36
Citations: 966

Most-cited papers

Cyclin D1 kinase activity is required for the self-renewal of mammary stem and progenitor cells that are targets of MMTV-ErbB2 tumorigenesis
R. Jeselsohn, Nelson E. Brown, L. Arendt, I. Klebba +3 more
2010Cancer Cell132 citations Open access
Semantic Scholar
Haploinsufficiency for BRCA1 leads to cell-type-specific genomic instability and premature senescence
Maja Sedic, Adam Skibinski, Nelson E. Brown, M. Gallardo +14 more
2015Nature Communications126 citations Open access
Semantic Scholar
Platelets, a Key Cell in Inflammation and Atherosclerosis Progression
R. Huilcaman, W. Venturini, Lucia Fuenzalida, Angel Cayo +4 more
2022Cells87 citations Open access
Semantic Scholar
mTOR Activity and Autophagy in Senescent Cells, a Complex Partnership
Angel Cayo, R. Segovia, W. Venturini, R. Moore-Carrasco +2 more
2021International Journal of Molecular Sciences82 citations Open access
Semantic Scholar
Cyclin D1 activity regulates autophagy and senescence in the mammary epithelium
Nelson E. Brown, R. Jeselsohn, Teeru Bihani, Miaofen G. Hu +3 more
2012Cancer Research77 citations Open access
Semantic Scholar
A truncated polycystin-2 protein causes polycystic kidney disease and retinal degeneration in transgenic rats.
A. Gallagher, S. Hoffmann, Nelson E. Brown, Anna Cedzich +8 more
2006Journal of the American Society of Nephrology70 citations
Semantic Scholar
Impaired bone development and increased mesenchymal progenitor cells in calvaria of RB1−/− mice
G. Gutierrez, Elizabeth Kong, Y. Sabbagh, Nelson E. Brown +4 more
2008Proceedings of the National Academy of Sciences of the United States of America67 citations Open access
Semantic Scholar
Palbociclib‐induced autophagy and senescence in gastric cancer cells
Claudio A. Valenzuela, Leandro Vargas, V. Martinez, S. Bravo +1 more
2017Experimental Cell Research63 citations Open access
Semantic Scholar
CDK6-mediated repression of CD25 is required for induction and maintenance of Notch1- induced T cell acute lymphoblastic leukemia
Nilamani Jena, Jing-Hao Sheng, Jamie K. Hu, Wei Li +11 more
2015Leukemia40 citations Open access
Semantic Scholar
TASK-3 Gene Knockdown Dampens Invasion and Migration and Promotes Apoptosis in KATO III and MKN-45 Human Gastric Adenocarcinoma Cell Lines
Rocio Cikutović-Molina, A. Herrada, W. González, Nelson E. Brown +1 more
2019International Journal of Molecular Sciences31 citations Open access
Semantic Scholar
TASK-3 Downregulation Triggers Cellular Senescence and Growth Inhibition in Breast Cancer Cell Lines
Rafael Zúñiga, Claudio A. Valenzuela, Guierdy Concha, Nelson E. Brown +1 more
2018International Journal of Molecular Sciences27 citations Open access
Semantic Scholar
Platelet Activation Is Triggered by Factors Secreted by Senescent Endothelial HMEC-1 Cells In Vitro
W. Venturini, Alexandra Olate-Briones, Claudio A. Valenzuela, Diego Méndez +6 more
2020International Journal of Molecular Sciences26 citations Open access
Semantic Scholar
The selective cytotoxicity elicited by phytochemical extract from Senecio graveolens (Asteraceae) on breast cancer cells is enhanced by hypoxia.
C. Echiburú-Chau, Susana Alfaro-Lira, Nelson E. Brown, C. Salas +4 more
2014International Journal of Oncology25 citations Open access
Semantic Scholar
SASP-Dependent Interactions between Senescent Cells and Platelets Modulate Migration and Invasion of Cancer Cells
Claudio A. Valenzuela, Ricardo Quintanilla, Alexandra Olate-Briones, W. Venturini +4 more
2019International Journal of Molecular Sciences24 citations Open access
Semantic Scholar
Use of the tetracycline system for inducible protein synthesis in the kidney.
A. Gallagher, K. Schönig, Nelson E. Brown, H. Bujard +1 more
2003Journal of the American Society of Nephrology19 citations Open access
Semantic Scholar
The Potential Role of Senescence As a Modulator of Platelets and Tumorigenesis
Claudio A. Valenzuela, Ricardo Quintanilla, R. Moore-Carrasco, Nelson E. Brown
2017Frontiers in Oncology17 citations Open access
Semantic Scholar
Expression and cellular localization of HCN channels in rat cerebellar granule neurons.
Rafael Zúñiga, Daniel González, Claudio A. Valenzuela, Nelson E. Brown +1 more
2016Biochemical and Biophysical Research Communications - BBRC15 citations
Semantic Scholar
The LxCxE pRb interaction domain of cyclin D1 is dispensable for murine development.
Mark W. Landis, Nelson E. Brown, G. Baker, Anna Shifrin +4 more
2007Cancer Research12 citations Open access
Semantic Scholar
Endothelial transmigration of platelets depends on soluble factors released by activated endothelial cells and monocytes
R. Huilcaman, Natalia Veliz-Olivos, W. Venturini, Alexandra Olate-Briones +4 more
2021Platelets10 citations
Semantic Scholar
Palbociclib-Induced Cellular Senescence Is Modulated by the mTOR Complex 1 and Autophagy
Angel Cayo, W. Venturini, D. Rebolledo-Mira, R. Moore-Carrasco +4 more
2023International Journal of Molecular Sciences9 citations Open access
Semantic Scholar
D-type Cyclins and Cancer
P. Hinds, Nelson E. Brown
2018Current cancer research4 citations Open access
Semantic Scholar
Faculty Opinions recommendation of Activated Ras requires autophagy to maintain oxidative metabolism and tumorigenesis.
P. Hinds, Nelson E. Brown
20112 citations
Semantic Scholar
Faculty of 1000 evaluation for A luminal epithelial stem cell that is a cell of origin for prostate cancer.
T. Visakorpi, P. Hinds, M. Roussel, O. Saramäki +1 more
20092 citations Open access
Semantic Scholar
Tumor-muscle communication in cancer-associated cachexia (Review)
L. Berríos-Contreras, Matías Meza‑Valenzuela, Nelson E. Brown, Claudio A. Valenzuela +4 more
2026Oncology Letters1 citations Open access
Semantic Scholar
Cyclin D1, Metabolism, and the Autophagy-Senescence Balance
Claudio A. Valenzuela, Nelson E. Brown
20181 citations Open access
Semantic Scholar
Faculty of 1000 evaluation for Pten in stromal fibroblasts suppresses mammary epithelial tumours.
F. Auricchio, Y. Takai, K. Yamada, Hisakazu Ogita +6 more
20121 citations
Semantic Scholar
Abstract 5983: The secretome produced by senescent gastric cancer cells can lead to different paracrine effects depending on the status of autophagy
Claudio A. Valenzuela, Danitza Rebolledo, Angel Cayo, W. Venturini +3 more
2023Cancer Research0 citations
Semantic Scholar
Abstract 1261: Detection of autophagy in gastric mucosae of Chilean individuals residing in a geographic region characterized by high rates of gastric cancer-related death
A. Corvalán, H. Pulgar, C. Cruzat, Nicole Céspedes +3 more
2018Prevention Research0 citations
Semantic Scholar
Abstract 2838: The role of cyclin D1-associated kinase activity in the regulation of autophagy and senescence in gastric cancer cells
Leandro Vargas, S. Bravo, Claudio A. Valenzuela, Nelson E. Brown
20160 citations
Semantic Scholar
830: Phytochemical extract from Senecio graveolens (Chachacoma): Searching new candidates for anti-cancer drugs
C. Echiburú-Chau, C. Salas, M. Cuellar, J. Santander +5 more
20140 citations
Semantic Scholar
3 – Tumor Suppressor Genes
Nelson E. Brown, P. Hinds
20140 citations
Semantic Scholar
Faculty of 1000 evaluation for Specific killing of Rb mutant cancer cells by inactivating TSC2.
P. Hinds, Nelson E. Brown
20120 citations
Semantic Scholar
Faculty Opinions recommendation of Suppression of autophagy by FIP200 deletion inhibits mammary tumorigenesis.
P. Hinds, Nelson E. Brown
20120 citations Open access
Semantic Scholar
Faculty of 1000 evaluation for Residual embryonic cells as precursors of a Barrett's-like metaplasia.
C. Blanpain, P. Hinds, Benjamin Beck, Yi-Xian Zheng +2 more
20110 citations
Semantic Scholar
Faculty Opinions recommendation of Oncogenic KRas suppresses inflammation-associated senescence of pancreatic ductal cells.
P. Hinds, Nelson E. Brown
20100 citations
Semantic Scholar
Abstract B26: Lack of cyclin D1 kinase activity leads to reduced levels of ErbB2-induced senescence and activation of the Wnt signaling pathway in the mammary gland
Nelson E. Brown, C. Kuperwasser, P. Hinds
20090 citations
Semantic Scholar

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