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J. Desjardins · SciRah

Researcher profile · Semantic Scholar

J. Desjardins

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J. Desjardins — researcher profile on SciRah

h-index: 18
Works: 102
Citations: 1,012

Most-cited papers

S100B Interaction With the Receptor for Advanced Glycation End Products (RAGE): A Novel Receptor-Mediated Mechanism for Myocyte Apoptosis Postinfarction
J. Tsoporis, Shehla Izhar, H. Leong-Poi, J. Desjardins +2 more
2010Circulation Research125 citations
Semantic Scholar
Empagliflozin Improves Diastolic Function in a Nondiabetic Rodent Model of Heart Failure With Preserved Ejection Fraction
K. Connelly, Yan-Ling Zhang, A. Visram, A. Advani +4 more
2019JACC: Basic to Translational Science110 citations Open access
Semantic Scholar
Sirtuin 1 activation attenuates cardiac fibrosis in a rodent pressure overload model by modifying Smad2/3 transactivation
Antoinette Bugyei-Twum, C. Ford, Robert A Civitarese, Jessica Seegobin +14 more
2018Cardiovascular Research90 citations Open access
Semantic Scholar
BRCA2 Protein Deficiency Exaggerates Doxorubicin-induced Cardiomyocyte Apoptosis and Cardiac Failure*
Krishna K. Singh, P. Shukla, A. Quan, J. Desjardins +13 more
2011Journal of Biological Chemistry59 citations Open access
Semantic Scholar
Load-independent effects of empagliflozin contribute to improved cardiac function in experimental heart failure with reduced ejection fraction
K. Connelly, Yan-Ling Zhang, J. Desjardins, L. Nghiem +7 more
2020Cardiovascular Diabetology55 citations Open access
Semantic Scholar
Dual inhibition of sodium–glucose linked cotransporters 1 and 2 exacerbates cardiac dysfunction following experimental myocardial infarction
K. Connelly, Yan-Ling Zhang, J. Desjardins, K. Thai +1 more
2018Cardiovascular Diabetology43 citations Open access
Semantic Scholar
Abstract 14465: Loss of BRCA2 in the Heart Induces Age-Related Cardiomyopathy
Krishna K. Singh, P. Shukla, A. Quan, J. Desjardins +9 more
201243 citations
Semantic Scholar
Lack of S100A1 in mice confers a gender-dependent hypertensive phenotype and increased mortality after myocardial infarction.
J. Desjardins, Ali Pourdjabbar, A. Quan, H. Leong-Poi +3 more
2009American Journal of Physiology. Heart and Circulatory Physiology40 citations
Semantic Scholar
Endothelial-specific Loss of IFT88 Promotes Endothelial-to-Mesenchymal Transition and Exacerbates Bleomycin-induced Pulmonary Fibrosis
Shweta Singh, Mohamed Adam, Pratiek N. Matkar, Antoinette Bugyei-Twum +14 more
2020Scientific Reports35 citations Open access
Semantic Scholar
The α11 integrin mediates fibroblast-extracellular matrix-cardiomyocyte interactions in health and disease.
Robert A Civitarese, Ilana Talior-Volodarsky, J. Desjardins, G. Kabir +6 more
2016American Journal of Physiology. Heart and Circulatory Physiology33 citations Open access
Semantic Scholar
Effects of pre-, peri-, and postmyocardial infarction treatment with losartan in rats: effect of dose on survival, ventricular arrhythmias, function, and remodeling.
Ali Pourdjabbar, T. Parker, Q. Nguyen, J. Desjardins +3 more
2005American Journal of Physiology. Heart and Circulatory Physiology29 citations
Semantic Scholar
Dipeptidyl peptidase‐4 inhibition improves cardiac function in experimental myocardial infarction: Role of stromal cell‐derived factor‐1α
K. Connelly, A. Advani, Yan-Ling Zhang, S. Advani +6 more
2016Journal of Diabetes28 citations
Semantic Scholar
Reduced encephalopathy in pigs with ischemia-induced acute hepatic failure treated with a bioartificial liver containing alginate-entrapped hepatocytes.
M. Desille, S. Mahler, P. Seguin, Y. Mallédant +9 more
2002Critical Care Medicine25 citations
Semantic Scholar
Cell-based therapy of acute liver failure: The extracorporeal bioartificial liver
B. Frémond, A. Joly, M. Desille, J. Desjardins +2 more
1996Cell Biology and Toxicology24 citations
Semantic Scholar
Endocannabinoid signaling enhances visual responses through modulation of intracellular chloride levels in retinal ganglion cells
Loïs S Miraucourt, Jennifer Tsui, Delphine Gobert, J. Desjardins +8 more
2016eLife23 citations Open access
Semantic Scholar
Absence of the calcium-binding protein, S100A1, confers pulmonary hypertension in mice associated with endothelial dysfunction and apoptosis.
K. Teichert-Kuliszewska, J. Tsoporis, J. Desjardins, Jun-Fei Yin +3 more
2015Cardiovascular Research23 citations
Semantic Scholar
Restoring myocardial infarction-induced long-term memory impairment by targeting the cystic fibrosis transmembrane regulator
Lotte Vanherle, Darcy Lidington, F. Uhl, Saskia Steiner +9 more
2022EBioMedicine20 citations Open access
Semantic Scholar
S100B: role in cardiac remodeling and function following myocardial infarction in diabetes.
F. Mohammadzadeh, J. Desjardins, J. Tsoporis, G. Proteau +2 more
2013Life Science18 citations
Semantic Scholar
Conditional cardiac overexpression of S100A6 attenuates myocyte hypertrophy and apoptosis following myocardial infarction.
Jim Tsoporis, Shehla Izhar, J. Desjardins, H. Leong-Poi +1 more
2014Current pharmaceutical design17 citations
Semantic Scholar
Therapeutic hypercapnia prevents inhaled nitric oxide-induced right-ventricular systolic dysfunction in juvenile rats.
Kristyn Dunlop, Kiranjot Gosal, C. Kantores, J. Ivanovska +6 more
2014Free Radical Biology & Medicine17 citations Open access
Semantic Scholar
Donor Mesenchymal Stromal Cells (MSCs) Undergo Variable Cardiac Reprogramming in Vivo and Predominantly Co-Express Cardiac and Stromal Determinants after Experimental Acute Myocardial Infarction
G. Yannarelli, J. Tsoporis, J. Desjardins, Xing-Hua Wang +4 more
2013Stem Cell Reviews and Reports16 citations Open access
Semantic Scholar
Rho kinase mediates right ventricular systolic dysfunction in rats with chronic neonatal pulmonary hypertension.
Kiranjot Gosal, Kristyn Dunlop, R. Dhaliwal, J. Ivanovska +6 more
2014American Journal of Respiratory Cell and Molecular Biology13 citations
Semantic Scholar
Effects of pre-, peri-, and postmyocardial infarction treatment with omapatrilat in rats: survival, arrhythmias, ventricular function, and remodeling.
N. Lapointe, Q. Nguyen, J. Desjardins, F. Marcotte +4 more
2003American Journal of Physiology. Heart and Circulatory Physiology13 citations
Semantic Scholar
Renal Tissue PO2 Sensing During Acute Hemodilution is Dependent on the Diluent.
J. R. Abrahamson, Austin D Read, Kyle Chin, Nikhil Mistry +12 more
2020American Journal of Physiology. Regulatory Integrative and Comparative Physiology12 citations
Semantic Scholar
Deficiency of S100B confers resistance to experimental diabetes in mice
F. Mohammadzadeh, J. Tsoporis, Shehla Izhar, J. Desjardins +1 more
2018Experimental Cell Research10 citations
Semantic Scholar
Experimental assessment of oxygen homeostasis during acute hemodilution: the integrated role of hemoglobin concentration and blood pressure
Tiffanie Kei, Nikhil Mistry, A. Tsui, E. Liu +7 more
2017Intensive Care Medicine Experimental10 citations Open access
Semantic Scholar
S100A1: a pluripotent regulator of cardiac and vascular function.
J. Desjardins, K. Teichert-Kuliszewska, T. Parker
2010Canadian Journal of Cardiology10 citations
Semantic Scholar
The SGLT2i Dapagliflozin Reduces RV Mass Independent of Changes in RV Pressure Induced by Pulmonary Artery Banding
K. Connelly, Ellen Wu, A. Visram, M. Friedberg +9 more
2022Cardiovascular Drugs and Therapy8 citations
Semantic Scholar
Results of Isolated Carotid Surgery in Patients with Vertebrobasilar Insufficiency
A. Cardon, Y. Kerdiles, A. Lucas, L. Podeur +3 more
1998Annals of Vascular Surgery8 citations
Semantic Scholar
The Goto Kakizaki rat: Impact of age upon changes in cardiac and renal structure, function
P. Meagher, Robert A Civitarese, X. Lee, M. Gordon +9 more
2021PLoS ONE7 citations Open access
Semantic Scholar
723 Dpp-4 Inhibition attenuates cardiac dysfunction and adverse remodelling following myocardial infarction in experimental diabetes
K. Connelly, J. Desjardins, A. Advani, G. Kabir +5 more
20116 citations Open access
Semantic Scholar
Late intervention in the remnant kidney model attenuates proteinuria but not glomerular filtration rate decline
Matthew R. Veitch, K. Thai, Yan-Ling Zhang, J. Desjardins +3 more
2020Nephrology5 citations
Semantic Scholar
Stoichiometry and Dispersity of DNA Nanostructures Using Photobleaching Pair-Correlation Analysis.
Amani A. Hariri, G. Hamblin, J. S. Hardwick, R. Godin +4 more
2017Bioconjugate chemistry5 citations Open access
Semantic Scholar
DJ-1 Deficiency Protects against Sepsis-Induced Myocardial Depression
J. Tsoporis, Hajera Amatullah, Sahil Gupta, Shehla Izhar +13 more
2023Antioxidants4 citations Open access
Semantic Scholar
EMPAGLIFLOZIN REDUCES LV MASS AND IMPROVES DIASTOLIC FUNCTION IN AN EXPERIMENTAL MODEL OF HEART FAILURE WITH PRESERVED EF
J. Desjardins, Yan-Ling Zhang, K. Thai, G. Kabir +2 more
20173 citations Open access
Semantic Scholar
ALPHA-11 INTEGRIN EXPRESSION IS ASSOCIATED WITH LEFT VENTRICULAR REMODELING: HUMAN AND CORRELATIVE EXPERIMENTAL STUDIES
Robert A Civitarese, I. Talior-Volodarsky, J. Desjardins, M. Mitchell +4 more
20143 citations Open access
Semantic Scholar
Lack of S 100 A 1 in mice confers a gender-dependent hypertensive phenotype and increased mortality after myocardial infarction
J. Desjardins, Ali Pourdjabbar, A. Quan, H. Leong-Poi +3 more
20093 citations
Semantic Scholar
Abstract 220: Critical Dependence on Timing of Cardiac Injection for Engraftment of Endothelial Progenitor Cells and Functional Benefit Post-Myocardial Infarction
E. Butler, J. Desjardins, H. Leong-Poi, Ali Pourdjabbar +2 more
20063 citations
Semantic Scholar
Altered coronary and cardiac adrenergic response in the failing hamster heart: role of cyclooxygenase derivatives.
D. Brousseau, J. Desjardins, G. Jasmin, L. Dumont
2002Canadian Journal of Physiology and Pharmacology3 citations
Semantic Scholar
Induction of proximal tubular proliferation and lengthening in response to sodium glucose linked cotransporter‐2 inhibition in experimental rats
Ellen Wu, Sarah Macklin, Yanling Zhang, K. Thai +11 more
2025Journal of Diabetes Investigation2 citations Open access
Semantic Scholar
Serial and regional assessment of the right ventricular molecular and functional response to pressure-loading.
Kana Yazaki, M. Dewar, John D. Dauz, Yohei Akazawa +8 more
2024American Journal of Physiology. Heart and Circulatory Physiology2 citations Open access
Semantic Scholar
776 DPP-4 Inhibition Improves Cardiac Function Following Experimental Myocardial Infarction: Potential Non-Glp-1 Mediated Effects
K. Connelly, Yan-Ling Zhang, A. Advani, S. Advani +5 more
20122 citations Open access
Semantic Scholar
Losartan and acute myocardial infarction in insulin-resistant Zucker fatty rats: reduced ventricular arrhythmias and improved survival.
Ali Pourdjabbar, T. Parker, J. Desjardins, Q. Nguyen +3 more
2005Canadian Journal of Physiology and Pharmacology2 citations
Semantic Scholar
Bilateral Nephrectomy Impairs Cardiovascular Function and Cerebral Perfusion in a Rat Model of Acute Hemodilutional Anemia.
Kyle Chin, Helen Jiang, Benjamin E. Steinberg, N. Goldenberg +12 more
2024Journal of applied physiology1 citations
Semantic Scholar
Inhibition of MRTF-A Ameliorates Pathological Remodeling of the Pressure-loaded Right Ventricle.
Mark F Rzepka, S. Raschzok, X. Lee, Kana Yazaki +10 more
2024American Journal of Respiratory Cell and Molecular Biology1 citations
Semantic Scholar
Abstract 12433: miR 187a-3p Prevents Septic-Induced Myocardial Dysfunction by Targeting the Inflammatory Cytokines TNFa and IL-6
A. Ektesabi, J. Tsoporis, C. Vaswani, Shehla Izhar +4 more
2023Circulation1 citations
Semantic Scholar
Abstract 16846: Activation of Farnesoid X Receptor Signaling Mediates Atrial Myocyte Apoptosis in Patients Undergoing On-Pump Coronary Artery Bypass Grafting and Ventricular Remodeling After Experimental Myocardial Infarction
J. Tsoporis, S. Izhar, J. Desjardins, V. Salpeas +2 more
20171 citations
Semantic Scholar
Abstract 16970: S100A6 Interacts With Melusin and Attenuates Stress-Induced Cardiomyocyte Apoptosis
J. Tsoporis, Shehla Izhar, J. Desjardins, H. Leong-Poi +1 more
20171 citations
Semantic Scholar
Abstract 19029: The Sirt1 Activator, SRT1720, Attenuates Cardiac Hypertrophy and Fibrosis in a Rodent Pressure Overload Model
C. Ford, Robert A Civitarese, Antoinette Bugyei-Twum, M. Mitchell +8 more
20141 citations
Semantic Scholar
Abstract 11698: Pulmonary Hypertension in S100A1 KO Mice is Associated With Endothelial Cell Dysfunction and Impaired eNOS Activation Dependent in Part on the Receptor for Advanced Glycation End-Products (RAGE)
K. Teichert-Kuliszewska, J. Desjardins, W. Kuebler, T. Parker
20141 citations
Semantic Scholar

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T. Parker×17
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K. Thai×14
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G. Kabir×14
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J. Tsoporis×11

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Ali Pourdjabbar×7

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Shehla Izhar×6

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