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J. D. de Boer · SciRah

Researcher profile · Semantic Scholar

J. D. de Boer

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J. D. de Boer — researcher profile on SciRah

h-index: 30
Works: 96
Citations: 2,414

Most-cited papers

VEGFB/VEGFR1-Induced Expansion of Adipose Vasculature Counteracts Obesity and Related Metabolic Complications
M. Robciuc, Riikka Kivelä, Ian M. Williams, J. D. de Boer +10 more
2016Cell Metabolism222 citations Open access
Semantic Scholar
Transintestinal Cholesterol Transport Is Active in Mice and Humans and Controls Ezetimibe-Induced Fecal Neutral Sterol Excretion.
L. Jakulj, T. V. van Dijk, J. D. de Boer, R. Kootte +9 more
2016Cell Metabolism144 citations Open access
Semantic Scholar
Myeloperoxidase and serum amyloid A contribute to impaired in vivo reverse cholesterol transport during the acute phase response but not group IIA secretory phospholipase A2[S]
W. Annema, N. Nijstad, M. Tölle, J. D. de Boer +4 more
2010Journal of Lipid Research138 citations Open access
Semantic Scholar
Intestinal Farnesoid X Receptor Controls Transintestinal Cholesterol Excretion in Mice.
J. D. de Boer, M. Schonewille, Marije Boesjes, H. Wolters +14 more
2017Gastroenterology135 citations Open access
Semantic Scholar
A human-like bile acid pool induced by deletion of hepatic Cyp2c70 modulates effects of FXR activation in mice
J. D. de Boer, E. Verkade, N. Mulder, H. D. de Vries +7 more
2019Journal of Lipid Research126 citations Open access
Semantic Scholar
HDL Cholesterol Efflux Predicts Graft Failure in Renal Transplant Recipients.
W. Annema, A. Dikkers, J. D. de Boer, R. Dullaart +3 more
2016Journal of the American Society of Nephrology81 citations Open access
Semantic Scholar
High-resolution imaging of human atherosclerotic carotid plaques with micro18F-FDG PET scanning exploring plaque vulnerability
Marleen G. Masteling, C. Zeebregts, R. Tio, J. Breek +6 more
2011Journal of Nuclear Cardiology71 citations Open access
Semantic Scholar
Cholesterol Transport Revisited: A New Turbo Mechanism to Drive Cholesterol Excretion.
J. D. de Boer, F. Kuipers, A. Groen
2018Trends in endocrinology and metabolism69 citations Open access
Semantic Scholar
Gremlin-1 Is an Inhibitor of Macrophage Migration Inhibitory Factor and Attenuates Atherosclerotic Plaque Growth in ApoE−/− Mice*
I. Müller, Tanja Schönberger, Martina Schneider, O. Borst +19 more
2013Journal of Biological Chemistry68 citations Open access
Semantic Scholar
Increased LCAT activity and hyperglycaemia decrease the antioxidative functionality of HDL
P. J. Kappelle, J. D. de Boer, F. Perton, W. Annema +3 more
2012European Journal of Clinical Investigation68 citations
Semantic Scholar
New insights in the multiple roles of bile acids and their signaling pathways in metabolic control
J. D. de Boer, V. Bloks, E. Verkade, M. Heiner-Fokkema +1 more
2018Current Opinion in Lipidology62 citations Open access
Semantic Scholar
HDL function is impaired in acute myocardial infarction independent of plasma HDL cholesterol levels.
W. Annema, H. M. Willemsen, J. D. de Boer, A. Dikkers +9 more
2016Journal of Clinical Lipidology61 citations Open access
Semantic Scholar
Impaired HDL cholesterol efflux in metabolic syndrome is unrelated to glucose tolerance status: the CODAM study
W. Annema, A. Dikkers, J. D. de Boer, M. V. van Greevenbroek +5 more
2016Scientific Reports60 citations Open access
Semantic Scholar
Cholangiopathy and Biliary Fibrosis in Cyp2c70-Deficient Mice Are Fully Reversed by Ursodeoxycholic Acid
J. D. de Boer, H. D. de Vries, A. Palmiotti, Ru-Mei Li +16 more
2020Cellular and Molecular Gastroenterology and Hepatology52 citations Open access
Semantic Scholar
Bile salts in control of lipid metabolism
M. Schonewille, J. D. de Boer, A. Groen
2016Current Opinion in Lipidology49 citations Open access
Semantic Scholar
Simvastatin and bezafibrate increase cholesterol efflux in men with type 2 diabetes
M. Triolo, W. Annema, J. D. de Boer, U. Tietge +1 more
2014European Journal of Clinical Investigation49 citations
Semantic Scholar
Bioenergetic cues shift FXR splicing towards FXRα2 to modulate hepatic lipolysis and fatty acid metabolism
J. Correia, J. Massart, J. D. de Boer, Margareta Porsmyr-Palmertz +11 more
2015Molecular Metabolism44 citations Open access
Semantic Scholar
Pancreatic β-cell function relates positively to HDL functionality in well-controlled type 2 diabetes mellitus.
R. Dullaart, W. Annema, J. D. de Boer, U. Tietge
2012Atherosclerosis43 citations
Semantic Scholar
Superoxide anions and hydrogen peroxide inhibit proliferation of activated rat stellate cells and induce different modes of cell death
S. Dunning, Rebekka A. Hannivoort, J. D. de Boer, M. Buist-Homan +2 more
2009Liver international (Print)41 citations
Semantic Scholar
Inhibition of DHCR24 activates LXRα to ameliorate hepatic steatosis and inflammation
E. Zhou, Xiao-Ke Ge, H. Nakashima, Ru-Mei Li +13 more
2023EMBO Molecular Medicine40 citations Open access
Semantic Scholar
Modulation of Bile Acid Metabolism to Improve Plasma Lipid and Lipoprotein Profiles
Bo-Yan Zhang, F. Kuipers, J. D. de Boer, J. Kuivenhoven
2021Journal of Clinical Medicine40 citations Open access
Semantic Scholar
Liver X Receptor Regulates Triglyceride Absorption Through Intestinal Down-regulation of Scavenger Receptor Class B, Type 1.
O. Briand, Veronique Touche, Sophie Colin, G. Brufau +14 more
2016Gastroenterology40 citations
Semantic Scholar
Overexpression of apolipoprotein O does not impact on plasma HDL levels or functionality in human apolipoprotein A-I transgenic mice.
N. Nijstad, J. D. de Boer, W. Lagor, M. Toelle +5 more
2011Biochimica et Biophysica Acta38 citations
Semantic Scholar
Plasma levels of PBEF/Nampt/visfatin are decreased in patients with liver cirrhosis.
J. D. de Boer, M. Bahr, K. Böker, M. Manns +1 more
2009American Journal of Physiology - Gastrointestinal and Liver Physiology38 citations
Semantic Scholar
Microbiome Modulation of the Host Adaptive Immunity through Bile Acid Modification.
F. Kuipers, J. D. de Boer, B. Staels
2020Cell Metabolism37 citations Open access
Semantic Scholar
Altered bile acid kinetics contribute to postprandial hypoglycaemia after Roux-en-Y gastric bypass surgery
M. van den Broek, L. D. de Heide, F. Sips, M. Koehorst +8 more
2021International Journal of Obesity35 citations Open access
Semantic Scholar
The inverse relation of HDL anti‐oxidative functionality with serum amyloid a is lost in metabolic syndrome subjects
R. Dullaart, J. D. de Boer, W. Annema, U. Tietge
2013Obesity34 citations Open access
Semantic Scholar
Lack of Abcg1 results in decreased plasma HDL cholesterol levels and increased biliary cholesterol secretion in mice fed a high cholesterol diet.
H. Wiersma, N. Nijstad, J. D. de Boer, Ruud Out +4 more
2009Atherosclerosis34 citations
Semantic Scholar
Glucose-6-Phosphate Regulates Hepatic Bile Acid Synthesis in Mice
J. Hoogerland, Y. Lei, J. Wolters, J. D. de Boer +12 more
2019Hepatology32 citations Open access
Semantic Scholar
Hepatic SREBP signaling requires SPRING to govern systemic lipid metabolism in mice and humans
S. Hendrix, Jenina Kingma, R. Ottenhoff, Masoud Valiloo +12 more
2023Nature Communications30 citations Open access
Semantic Scholar
Sphingosine kinase-1 inhibition protects primary rat hepatocytes against bile salt-induced apoptosis.
Golnar Karimian, M. Buist-Homan, M. Schmidt, U. Tietge +7 more
2013Biochimica et Biophysica Acta30 citations Open access
Semantic Scholar
Skin autofluorescence is inversely related to HDL anti-oxidative capacity in type 2 diabetes mellitus.
D. Mulder, J. D. de Boer, R. Graaff, R. D. De Vries +5 more
2011Atherosclerosis29 citations Open access
Semantic Scholar
Low production of 12α-hydroxylated bile acids prevents hepatic steatosis in Cyp2c70−/− mice by reducing fat absorption
Ru-Mei Li, A. Palmiotti, H. D. de Vries, M. Hovingh +9 more
2021Journal of Lipid Research26 citations Open access
Semantic Scholar
Transintestinal and Biliary Cholesterol Secretion Both Contribute to Macrophage Reverse Cholesterol Transport in Rats—Brief Report
J. D. de Boer, M. Schonewille, A. Dikkers, M. Koehorst +4 more
2017Arteriosclerosis, Thrombosis and Vascular Biology25 citations Open access
Semantic Scholar
Combined GIP receptor and GLP1 receptor agonism attenuates NAFLD in male APOE∗3-Leiden.CETP mice
Z. Ying, R. van Eenige, Xiao-Ke Ge, Christy van Marwijk +10 more
2023EBioMedicine23 citations Open access
Semantic Scholar
Developments in intestinal cholesterol transport and triglyceride absorption
Y. Paalvast, J. D. de Boer, A. Groen
2017Current Opinion in Lipidology22 citations Open access
Semantic Scholar
Potential of Intestine-Selective FXR Modulation for Treatment of Metabolic Disease.
T. van Zutphen, A. Bertolini, H. D. de Vries, V. Bloks +3 more
2019Handbook of Experimental Pharmacology20 citations Open access
Semantic Scholar
Low normal free T4 confers decreased high‐density lipoprotein antioxidative functionality in the context of hyperglycaemia
M. Triolo, J. D. de Boer, W. Annema, A. Kwakernaak +2 more
2013Clinical Endocrinology19 citations
Semantic Scholar
Hepatic ABCG5/G8 overexpression substantially increases biliary cholesterol secretion but does not impact in vivo macrophage-to-feces RCT.
A. Dikkers, J. D. de Boer, A. Groen, U. Tietge
2015Atherosclerosis18 citations
Semantic Scholar
Gut microbiota depletion aggravates bile acid-induced liver pathology in mice with a human-like bile acid composition
E. Verkade, Wen-Qiang Shen, M. Hovingh, N. Mulder +6 more
2023Clinical science16 citations Open access
Semantic Scholar
Rosiglitazone Attenuates Transplant Arteriosclerosis After Allogeneic Aorta Transplantation in Rats
G. Onuta, H. Rienstra, J. D. de Boer, M. Boer +6 more
2007Transplantation16 citations Open access
Semantic Scholar
Differential impact of hepatic deficiency and total body inhibition of MTP on cholesterol metabolism and RCT in mice[S]
A. Dikkers, W. Annema, J. D. de Boer, J. Iqbal +2 more
2014Journal of Lipid Research15 citations Open access
Semantic Scholar
New insights in amino sugar metabolism by the gut microbiome
Wen-Qiang Shen, J. D. de Boer, F. Kuipers, Jing-Yuan Fu
2025Gut microbes14 citations Open access
Semantic Scholar
Emerging drugs for the treatment of progressive familial intrahepatic cholestasis: a focus on phase II and III trials
Willemien F. J. Hof, J. D. de Boer, H. Verkade
2024Expert Opinion on Emerging Drugs14 citations Open access
Semantic Scholar
Maternal antibiotic prophylaxis during cesarean section has a limited impact on the infant gut microbiome
T. Sinha, J. Prins, Asier Fernández-Pato, Marloes Kruk +7 more
2024Cell Host and Microbe14 citations Open access
Semantic Scholar
Combined glucose-dependent insulinotropic polypeptide receptor and glucagon-like peptide-1 receptor agonism attenuates atherosclerosis severity in APOE*3-Leiden.CETP mice.
R. van Eenige, Z. Ying, N. Tramper, Vera Wiebing +9 more
2023Atherosclerosis14 citations Open access
Semantic Scholar
Inhibiting Cholesterol Absorption During Lactation Programs Future Intestinal Absorption of Cholesterol in Adult Mice.
Lidiya G. Dimova, J. D. de Boer, J. Plantinga, T. Plösch +3 more
2017Gastroenterology13 citations
Semantic Scholar
Mitogen-Activated Protein Kinase-Activated Protein Kinase 2 Deficiency Reduces Insulin Sensitivity in High-Fat Diet-Fed Mice
J. D. de Boer, A. Dikkers, A. Jurdzinski, J. von Felden +3 more
2014PLoS ONE13 citations Open access
Semantic Scholar
Short-term obeticholic acid treatment does not impact cholangiopathy in Cyp2c70-deficient mice with a human-like bile acid composition.
Ru-Mei Li, M. Hovingh, M. Koehorst, P. de Blaauw +3 more
2022Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids12 citations Open access
Semantic Scholar
A Human-like Bile Acid Pool Induced by Deletion of Hepatic Cyp2c70 Modulates Effects of Farnesoid X Receptor Activation in Mice
J. D. de Boer, E. Verkade, N. Mulder, H. D. de Vries +8 more
201912 citations
Semantic Scholar

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A. Groen×11
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M. Schonewille — researcher profile on SciRah