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H. Kai · SciRah

Researcher profile · Semantic Scholar

H. Kai

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H. Kai — researcher profile on SciRah

h-index: 19
Works: 79
Citations: 1,427

Most-cited papers

Accelerated tumor growth in mice deficient in DNAM-1 receptor
A. Iguchi-Manaka, H. Kai, Y. Yamashita, K. Shibata +6 more
2008Journal of Experimental Medicine280 citations Open access
Semantic Scholar
Tumor rejection by the poliovirus receptor family ligands of the DNAM-1 (CD226) receptor.
S. Tahara-Hanaoka, K. Shibuya, H. Kai, A. Miyamoto +4 more
2006Blood146 citations Open access
Semantic Scholar
Essential points from Evidence-based Clinical Practice Guidelines for Chronic Kidney Disease 2018
H. Okada, Y. Yasuda, N. Kashihara, K. Asahi +139 more
2018Clinical and Experimental Nephrology141 citations Open access
Semantic Scholar
Mitochondrial DNA mutations in focal segmental glomerulosclerosis lesions.
K. Yamagata, K. Muro, J. Usui, M. Hagiwara +7 more
2002Journal of the American Society of Nephrology72 citations Open access
Semantic Scholar
Measurement of health-related quality of life in patients with chronic kidney disease in Japan with EuroQol (EQ-5D)
R. Tajima, M. Kondo, H. Kai, C. Saito +5 more
2010Clinical and Experimental Nephrology64 citations
Semantic Scholar
Critical role of DNAX accessory molecule-1 (DNAM-1) in the development of acute graft-versus-host disease in mice
T. Nabekura, K. Shibuya, E. Takenaka, H. Kai +6 more
2010Proceedings of the National Academy of Sciences of the United States of America60 citations Open access
Semantic Scholar
Single-cell analyses and host genetics highlight the role of innate immune cells in COVID-19 severity
R. Edahiro, Y. Shirai, Yusuke Takeshima, S. Sakakibara +450 more
2023Nature Genetics58 citations Open access
Semantic Scholar
Predominance of Type-2 Immune Response in Idiopathic Membranous Nephropathy
K. Hirayama, I. Ebihara, Satoshi Yamamoto, H. Kai +4 more
2002Nephron54 citations
Semantic Scholar
A critical role of LFA-1 in the development of Th17 cells and induction of experimental autoimmune encephalomyelytis.
Yi-Nan Wang, H. Kai, Fei Chang, K. Shibata +4 more
2007Biochemical and Biophysical Research Communications - BBRC44 citations
Semantic Scholar
Critical role of M. tuberculosis for dendritic cell maturation to induce collagen‐induced arthritis in H‐2b background of C57BL/6 mice
H. Kai, K. Shibuya, Yi-Nan Wang, H. Kameta +8 more
2006Immunology40 citations Open access
Semantic Scholar
LFA-1 decreases the antigen dose for T cell activation in vivo.
Yi-Nan Wang, K. Shibuya, Y. Yamashita, J. Shirakawa +7 more
2008International Immunology36 citations
Semantic Scholar
Post-MRSA infection glomerulonephritis with marked Staphylococcus aureus cell envelope antigen deposition in glomeruli.
H. Kai, Y. Shimizu, M. Hagiwara, Keigyou Yoh +5 more
2006JN. Journal of Nephrology (Milano. 1992)33 citations
Semantic Scholar
Health-related quality of life and prognosis in patients with chronic kidney disease: a 3-year follow-up study
R. Okubo, H. Kai, M. Kondo, C. Saito +4 more
2014Clinical and Experimental Nephrology31 citations
Semantic Scholar
Anaemia is an essential complication of ANCA-associated renal vasculitis: a single center cohort study
T. Kawamura, J. Usui, Shuzo Kaneko, Ryoya Tsunoda +6 more
2017BMC Nephrology29 citations Open access
Semantic Scholar
The whole blood transcriptional regulation landscape in 465 COVID-19 infected samples from Japan COVID-19 Task Force
Qing-Bo S. Wang, R. Edahiro, H. Namkoong, Takanori Hasegawa +439 more
2022Nature Communications28 citations Open access
Semantic Scholar
A digest from evidence-based Clinical Practice Guideline for Polycystic Kidney Disease 2020
S. Nishio, K. Tsuchiya, S. Nakatani, S. Muto +27 more
2021Clinical and Experimental Nephrology26 citations
Semantic Scholar
Heterogeneity of prognosis in adult IgA nephropathy, especially with mild proteinuria or mild histological features.
J. Usui, K. Yamagata, H. Kai, Takaaki Outeki +10 more
2001Internal medicine26 citations
Semantic Scholar
Cystic Kidney Diseases That Require a Differential Diagnosis from Autosomal Dominant Polycystic Kidney Disease (ADPKD)
Akinari Sekine, S. Hidaka, T. Moriyama, Yasuto Shikida +27 more
2022Journal of Clinical Medicine24 citations Open access
Semantic Scholar
Japan COVID-19 Task Force: a nation-wide consortium to elucidate host genetics of COVID-19 pandemic in Japan
H. Namkoong, R. Edahiro, K. Fukunaga, Y. Shirai +448 more
2021medRxiv19 citations Open access
Semantic Scholar
Comparison of annual eGFR decline among primary kidney diseases in patients with CKD G3b-5: results from a REACH-J CKD cohort study
J. Hoshino, Ryoya Tsunoda, K. Nagai, H. Kai +14 more
2021Clinical and Experimental Nephrology18 citations
Semantic Scholar
Effects of irbesartan on inflammatory cytokine concentrations in patients with chronic glomerulonephritis.
S. Tsuruoka, H. Kai, J. Usui, N. Morito +3 more
2013Internal medicine18 citations Open access
Semantic Scholar
Annual incidence of persistent proteinuria in the general population from Ibaraki annual urinalysis study
K. Nagai, C. Saito, Fumiyo Watanabe, Reiko Ohkubo +8 more
2013Clinical and Experimental Nephrology16 citations
Semantic Scholar
A nationwide prospective cohort study of patients with advanced chronic kidney disease in Japan: The Reach-J CKD cohort study
J. Hoshino, K. Nagai, H. Kai, C. Saito +13 more
2018Clinical and Experimental Nephrology14 citations
Semantic Scholar
Angiopoietin Balance in Septic Shock Patients Treated by Direct Hemoperfusion With Polymyxin B‐immobilized Fiber
I. Ebihara, K. Hirayama, K. Nagai, Tomoko Kakita +9 more
2009Therapeutic apheresis and dialysis12 citations
Semantic Scholar
TMPRSS2 gene polymorphism common in East Asians confers decreased COVID-19 susceptibility
Takeshi Sekiya, Y. Ogura, H. Kai, Atsushi Kawaguchi +15 more
2022Frontiers in Microbiology10 citations Open access
Semantic Scholar
Temporal Changes in Post-Infectious Glomerulonephritis in Japan (1976-2009)
J. Usui, Takashi Tawara-Iida, K. Takada, I. Ebihara +16 more
2016PLoS ONE9 citations Open access
Semantic Scholar
Physical activity and renal outcome in diabetic and non-diabetic patients with chronic kidney disease stage G3b to G5
Junichi Hoshino, Tomohiro Ohigashi, Ryoya Tsunoda, Yukiko Ito +9 more
2024Scientific Reports8 citations Open access
Semantic Scholar
Gastrointestinal symptoms in COVID-19 and disease severity: a Japanese registry-based retrospective cohort study
Yutaku Matsubara, H. Kiyohara, Y. Mikami, K. Nanki +461 more
2024Journal of gastroenterology8 citations
Semantic Scholar
Cost-Effectiveness of Behavior Modification Intervention for Patients With Chronic Kidney Disease in the FROM-J Study.
R. Okubo, M. Kondo, S. Hoshi, M. Okada +12 more
2021Journal of renal nutrition8 citations Open access
Semantic Scholar
Literature review of allograft adenovirus nephritis and a case presenting as mass lesions in a transplanted kidney without symptoms of urinary tract infection or acute kidney injury
Megumi Watanabe, Shuzo Kaneko, J. Usui, Kazuhiro Takahashi +15 more
2020Transplant Infectious Disease8 citations
Semantic Scholar
Polyclonal activation of an IgA subclass against Staphylococcus aureus cell membrane antigen in post-methicillin-resistant S. aureus infection glomerulonephritis.
Y. Arakawa, Y. Shimizu, Hideko Sakurai, S. Kawamura +8 more
2006Nephrology, Dialysis and Transplantation7 citations
Semantic Scholar
Secondary membranous glomerulonephritis associated with recipient residual lymphoma cells after allogeneic bone marrow transplantation
K. Sakai, J. Usui, H. Kai, M. Hagiwara +8 more
2009Clinical and Experimental Nephrology6 citations
Semantic Scholar
Host control of persistent Epstein–Barr virus infection
A. Schmidt, T. M. Alawathurage, F. David, Yosuke Ogawa +496 more
2026Nature5 citations Open access
Semantic Scholar
Associations of anaemia and iron deficiency with health-related quality of life in patients with chronic kidney disease stage G3b-5 in Japan: sub analysis of the Reach-J CKD cohort study
R. Okubo, Tomohiro Ohigashi, M. Kondo, Ryoya Tsunoda +8 more
2024BMC Nephrology5 citations Open access
Semantic Scholar
Renal Hemodynamic and Functional Changes in Patients with ADPKD
Ryota Ishii, H. Kai, Kentaro Nakajima, Takuya Harada +9 more
2024Kidney3605 citations Open access
Semantic Scholar
A case report of progressive multifocal leukoencephalopathy during steroid treatment for ANCA-associated renal vasculitis
T. Tawara, H. Kai, Mikiko Kageyama, T. Akiyama +11 more
2020CEN Case Reports5 citations Open access
Semantic Scholar
Kidney Function Trajectories with Tolvaptan in ADPKD Patients with CKD-G5
Akinari Sekine, Junichi Hoshino, Toshio Mochizuki, Shinya Nakatani +20 more
2025Kidney International Reports4 citations Open access
Semantic Scholar
Public support for patients with intractable diseases in Japan: impact on clinical indicators from nationwide registries in patients with autosomal dominant polycystic kidney disease
H. Kataoka, Yosuke Shimada, Tomonori Kimura, S. Nishio +34 more
2023Clinical and Experimental Nephrology4 citations
Semantic Scholar
Health-related quality of life in 10 years long-term survivors of chronic kidney disease: a From-J study.
R. Okubo, M. Kondo, Toshiyuki Imasawa, C. Saito +9 more
2023Journal of renal nutrition4 citations Open access
Semantic Scholar
Long-term Effectiveness of a Primary Care Practice Facilitation Program for Chronic Kidney Disease Management: An Extended Follow-up of a Cluster-Randomized FROM-J Study.
T. Imasawa, C. Saito, H. Kai, K. Iseki +20 more
2022Nephrology, Dialysis and Transplantation4 citations
Semantic Scholar
Anti-glomerular Basement Membrane Glomerulonephritis During the First Trimester of Pregnancy
H. Kai, J. Usui, T. Tawara, Mayumi Takahashi-Kobayashi +9 more
2020Internal medicine4 citations Open access
Semantic Scholar
Effectiveness of Plasmapheresis in a Patient with Anti-glomerular Basement Membrane Antibody Glomerulonephritis with Advanced Kidney Dysfunction
Toshiaki Usui, H. Kai, Kazuyuki Noguchi, N. Morito +5 more
2017Internal medicine4 citations Open access
Semantic Scholar
Evaluation of the Validity of a Novel CKD Assessment Checklist Used in the Frontier of Renal Outcome Modifications in Japan Study.
H. Kai, Mariko Doi, Masafumi Okada, Kohsuke Yamada +3 more
2016Journal of renal nutrition4 citations
Semantic Scholar
Crescentic glomerulonephritis associated with renal cell carcinoma after cancer immunotherapy.
H. Kai, Kunihiro Yamagata, J. Usui, Y. Shimizu +9 more
2005JN. Journal of Nephrology (Milano. 1992)4 citations
Semantic Scholar
Efficacy and Safety of Dotinurad in Patients with Advanced Chronic Kidney Disease
Teppei Motomura, Mayuka Higashi, Akihisa Hattori, Ryosuke Akiyama +1 more
2025Internal medicine3 citations Open access
Semantic Scholar
Multiple Myeloma in a Patient with Birt-Hogg-Dubé Syndrome
F. Matsumura, Tatsuhiro Sakamoto, H. Kai, Toshiaki Usui +16 more
2025Internal medicine3 citations Open access
Semantic Scholar
Anti-PM/Scl Antibody-positive Systemic Sclerosis Complicated by Multiple Organ Involvement
Tatsuya Shimizu, C. Saito, Megumi Watanabe, Ryota Ishii +12 more
2020Internal medicine3 citations Open access
Semantic Scholar
Physical functioning in patients with chronic kidney disease stage G3b‐5 in Japan: The reach‐J CKD cohort study
R. Okubo, M. Kondo, Ryoya Tsunoda, K. Nagai +9 more
2021Nephrology2 citations
Semantic Scholar
Ratio of serum creatinine to cystatin C is related to leg strength in predialysis CKD patients
Kohei Shiomi, C. Saito, K. Nagai, K. Kosaki +7 more
2021Clinical and Experimental Nephrology2 citations
Semantic Scholar
Two autosomal dominant polycystic kidney (ADPKD) cases with advanced renal dysfunction, effectively treated with tolvaptan
H. Kai, Yukino Shinozaki, Airi Nishikubo, Megumi Watanabe +12 more
2016CEN Case Reports2 citations Open access
Semantic Scholar

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