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C. Tregnago · SciRah

Researcher profile · Semantic Scholar

C. Tregnago

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C. Tregnago — researcher profile on SciRah

h-index: 13
Works: 57
Citations: 591

Most-cited papers

Drp1 Controls Effective T Cell Immune-Surveillance by Regulating T Cell Migration, Proliferation, and cMyc-Dependent Metabolic Reprogramming
Luca Simula, I. Pacella, Alessandra Colamatteo, C. Procaccini +10 more
2018Cell Reports119 citations Open access
Semantic Scholar
NUP98-fusion transcripts characterize different biological entities within acute myeloid leukemia: a report from the AIEOP-AML group
V. Bisio, M. Zampini, C. Tregnago, E. Manara +14 more
2017Leukemia53 citations Open access
Semantic Scholar
MLL-AF6 fusion oncogene sequesters AF6 into the nucleus to trigger RAS activation in myeloid leukemia.
E. Manara, Emma Baron, C. Tregnago, S. Aveic +6 more
2014Blood47 citations Open access
Semantic Scholar
MicroRNA-34b promoter hypermethylation induces CREB overexpression and contributes to myeloid transformation
M. Pigazzi, E. Manara, S. Bresolin, C. Tregnago +8 more
2013Haematologica42 citations Open access
Semantic Scholar
Characterization of children with FLT3-ITD acute myeloid leukemia: a report from the AIEOP AML-2002 study group
E. Manara, G. Basso, M. Zampini, B. Buldini +14 more
2017Leukemia40 citations
Semantic Scholar
Minimal residual disease monitored after induction therapy by RQ-PCR can contribute to tailor treatment of patients with t(8;21) RUNX1-RUNX1T1 rearrangement
M. Pigazzi, E. Manara, B. Buldini, Valzerda Beqiri +10 more
2015Haematologica40 citations Open access
Semantic Scholar
Targeting mesenchymal stromal cells plasticity to reroute acute myeloid leukemia course.
G. Borella, A. Da Ros, G. Borile, E. Porcù +16 more
2021Blood31 citations Open access
Semantic Scholar
Label-free, real-time on-chip sensing of living cells via grating-coupled surface plasmon resonance.
G. Borile, S. Rossi, A. Filippi, E. Gazzola +4 more
2019Biophysical Chemistry29 citations
Semantic Scholar
CREB engages C/EBPδ to initiate leukemogenesis
C. Tregnago, E. Manara, M. Zampini, V. Bisio +6 more
2016Leukemia28 citations Open access
Semantic Scholar
ZNF521 sustains the differentiation block in MLL-rearranged acute myeloid leukemia
G. Germano, Giulia Morello, S. Aveic, M. Pinazza +11 more
2017OncoTarget23 citations Open access
Semantic Scholar
Epigenetic heterogeneity affects the risk of relapse in children with t(8;21)RUNX1-RUNX1T1-rearranged AML
M. Zampini, C. Tregnago, V. Bisio, Luca Simula +12 more
2018Leukemia21 citations Open access
Semantic Scholar
Molecular Measurable Residual Disease Assessment before Hematopoietic Stem Cell Transplantation in Pediatric Acute Myeloid Leukemia Patients: A Retrospective Study by the I-BFM Study Group
M. Benetton, P. Merli, C. Walter, M. Hansen +12 more
2022Biomedicines13 citations Open access
Semantic Scholar
The long non-coding RNA CDK6-AS1 overexpression impacts on acute myeloid leukemia differentiation and mitochondrial dynamics
E. Porcù, M. Benetton, V. Bisio, A. Da Ros +10 more
2021iScience13 citations Open access
Semantic Scholar
CD56, HLA‐DR, and CD45 recognize a subtype of childhood AML harboring CBFA2T3‐GLIS2 fusion transcript
A. Zangrando, F. Cavagnero, P. Scarparo, E. Varotto +14 more
2021Cytometry Part A13 citations Open access
Semantic Scholar
Novel Compounds Synergize With Venetoclax to Target KMT2A-Rearranged Pediatric Acute Myeloid Leukemia
C. Tregnago, M. Benetton, A. Da Ros, G. Borella +5 more
2022Frontiers in Pharmacology10 citations Open access
Semantic Scholar
A three‐miRNA‐based expression signature at diagnosis can predict occurrence of relapse in children with t(8;21) RUNX1‐RUNX1T1 acute myeloid leukaemia
M. Zampini, V. Bisio, A. Leszl, M. Putti +7 more
2018British Journal of Haematology9 citations
Semantic Scholar
Thioridazine requires calcium influx to induce MLL-AF6-rearranged AML cell death.
C. Tregnago, A. Da Ros, E. Porcù, M. Benetton +13 more
2020Blood Advances8 citations Open access
Semantic Scholar
ICER Evokes Dusp1-p38 Pathway Enhancing Chemotherapy Sensitivity in Myeloid Leukemia
M. Pigazzi, E. Manara, A. Beghin, Emma Baron +2 more
2011Clinical Cancer Research8 citations Open access
Semantic Scholar
NPM1 Mutational Status Underlines Different Biological Features in Pediatric AML
C. Tregnago, M. Benetton, Davide Padrin, Katia Polato +8 more
2021Cancers6 citations Open access
Semantic Scholar
Acute Myeloid Leukemia (AML) in a 3D Bone Marrow Niche Showed High Performance for in Vitro and In Vivo Drug Screenings
G. Borella, A. Da Ros, E. Porcù, C. Tregnago +9 more
2019Blood6 citations Open access
Semantic Scholar
Leukemic Cells Hijack Stromal Bioelectricity to Reprogram the Bone Marrow Niche via CaV1.2‐Dependent Mechanisms
A. Da Ros, M. Benetton, G. Borella, G. Longo +8 more
2025Advancement of science4 citations Open access
Semantic Scholar
Influence of Nucleophosmin (NPM1) Genotypes on Outcome of Patients with Acute Myeloid Leukemia: an AIEOP-BFM and COG-SWOG Intergroup Collaboration
C. Tregnago, M. Benetton, R. Ries, Jack H. Peplinski +13 more
2024Journal of Clinical Oncology3 citations Open access
Semantic Scholar
CD72 is a pan‐tumor antigen associated to pediatric acute leukemia
B. Buldini, Giovanni Faggin, E. Porcù, P. Scarparo +8 more
2023Cytometry Part A3 citations Open access
Semantic Scholar
Long Non Coding RNA BALR2-CDK6 Axis Influences Cell Differentiation and Metabolic Status of Acute Myeloid Leukemia
V. Bisio, C. Tregnago, M. Zampini, G. Borella +6 more
20173 citations
Semantic Scholar
Advancing precision therapy in pediatric acute myeloid leukemia through PDX models and mitochondrial targeting
A. Da Ros, Alberto Peloso, G. Longo, M. Benetton +10 more
2026Blood Advances2 citations Open access
Semantic Scholar
CD72 Is a Pan-Tumor Antigen Associated with Childhood Acute Leukemia
B. Buldini, Giovanni Faggin, E. Porcù, P. Scarparo +8 more
2022Blood2 citations Open access
Semantic Scholar
Impact of Minimal Residual Disease (MRD) Assessed before Transplantation on the Outcome of Children with Acute Myeloid Leukemia Given an Allograft: A Retrospective Study By the I-BFM Study Group
M. Pigazzi, M. Benetton, C. Walter, M. Hansen +13 more
20202 citations
Semantic Scholar
Prognostic Value of Molecular Genetic Measurable Residual Disease (MRD) Monitoring in Pediatric Acute Myeloid Leukemia Expressing KMT2A::MLLT10
E. Steidel, Eser Orhan, Mareike Rasche, M. Pigazzi +9 more
2025European Journal of Haematology1 citations Open access
Semantic Scholar
Soluble factors in the AML secretome drive macrophage polarization toward an M2-like state promoting an immunosuppressive microenvironment
G. Longo, C. Tregnago, Sara Perpinello, A. Da Ros +8 more
2025Blood1 citations
Semantic Scholar
Leukemic Cells Manipulate MSCs Bioelectrical Signals to Reshape the Bone Marrow Niche
G. Borella, M. Benetton, A. Da Ros, G. Longo +8 more
2025bioRxiv1 citations Open access
Semantic Scholar
Characterization of the Molecular Landscape of Pediatric Acute Myeloid Leukemia: A Retrospective AIEOP AML2013/01 Study
M. Benetton, P. Merli, N. Santoro, L. Lo Nigro +14 more
2023Blood1 citations Open access
Semantic Scholar
Bioelectric Reprogramming of the Bone Marrow Niche in Acute Myeloid Leukemia
G. Borella, M. Benetton, A. Da Ros, G. Longo +8 more
2023Blood1 citations Open access
Semantic Scholar
DNMT3A Mutants Are Enriched in NPMc+ AML and Associated with Adverse Outcome in Childhood AML
R. Ries, Xiao-Tu Ma, C. Tregnago, T. Alonzo +12 more
2023Blood1 citations Open access
Semantic Scholar
Prognostic Role of Molecular MRD Variations during Treatment of Pediatric AML: A Retrospective AIEOP AML2013/01 Study
M. Pigazzi, M. Benetton, P. Merli, Rosanna Cuccurullo +11 more
2023Blood1 citations Open access
Semantic Scholar
Nucleophosmin (NPM1) Type D Genotype Is Associated with Distinct Outcome in Acute Myeloid Leukemia - an AIEOP-BFM and COG-SWOG Intergroup Collaboration
M. Pigazzi, C. Tregnago, R. Ries, M. Benetton +10 more
2023Blood1 citations Open access
Semantic Scholar
Mesenchymal Stromal Cell Secretome in Acute Myeloid Leukemia Bone Marrow Niche
G. Borella, G. Longo, A. Da Ros, Elisabetta Campodoni +8 more
2022Blood1 citations Open access
Semantic Scholar
Label-free, real-time on-chip sensing of living cancer cell via grating-coupled surface plasmon resonance
G. Borile, S. Rossi, A. Filippi, E. Gazzola +4 more
2019bioRxiv1 citations Open access
Semantic Scholar
PS1226 DEVELOPMENT OF INNOVATIVE PRECLINICAL IN VITRO AND IN VIVO TOOLS FOR AN EFFECTIVE THERAPEUTIC STRATEGY IN PEDIATRIC ACUTE MYELOID LEUKEMIA
G. Borella, V. Bisio, A. Da Ros, C. Tregnago +8 more
2019HemaSphere1 citations Open access
Semantic Scholar
Rhob Overexpression Boosts Relapse of t(8;21) RUNX1-RUNX1T1 Rearranged Acute Myeloid Leukemia.
P. Martina, Zampini Matteo, C. Tregnago, V. Bisio +10 more
20171 citations
Semantic Scholar
Dna Methylation Is Linked to a Specific Cell-Adhesion Program in Relapsed Pediatric t(8;21)(q22;q22)RUNX1-RUNX1T1 Patients
M. Zampini, C. Tregnago, V. Bisio, B. Accordi +9 more
20161 citations
Semantic Scholar
MiR-34b Promoter Methylation and Regulation of CREB Expression In Myeloid Transformation
E. Manara, Emma Baron, A. Beghin, C. Tregnago +4 more
20101 citations
Semantic Scholar
Reactive oxygen species define leukemia stem cell identity in pediatric acute myeloid leukemia.
M. Benetton, A. Da Ros, Alberto Peloso, G. Longo +11 more
2026Cancer Letters0 citations Open access
Semantic Scholar
KMT2A::AF6 fusion protein localizes to PML nuclear bodies and undergoes ATO-induced degradation: A potential novel therapeutic approach for KMT2A::AF6-rearranged Acute Myeloid Leukemia
C. Tregnago, Sara Perpinello, A. Da Ros, M. Benetton +6 more
2025Blood0 citations
Semantic Scholar
Next generation sequencing profiling of pediatric Acute Myeloid Leukemia reveals distinct genetic landscapes across cytogenetic subgroups
M. Benetton, C. Tregnago, Katia Polato, Diego Calvetti +11 more
2025Blood0 citations
Semantic Scholar
Novel Promising Therapeutic Strategies for Advancing the Treatment of KMT2A-Rearranged AML
A. Da Ros, Alberto Peloso, G. Longo, M. Benetton +10 more
2024Blood0 citations Open access
Semantic Scholar
Pursuing Leukemia Stem Cells Definition in Pediatric Acute Myeloid Leukemia
M. Benetton, A. Da Ros, Alberto Peloso, G. Longo +8 more
2024Blood0 citations
Semantic Scholar
P414: PATIENT-DERIVED XENOGRAFT MODELS ARE THE LEADING STRATEGY TO IDENTIFY NEW AGENTS FOR PEDIATRIC ACUTE MYELOID LEUKEMIA
A. Da Ros, V. Indio, Alberto Peloso, C. Tregnago +8 more
2023HemaSphere0 citations Open access
Semantic Scholar
P435: NOVEL COMPOUNDS TO TARGET KMT2A-REARRANGED PEDIATRIC ACUTE MYELOID LEUKEMIA
C. Tregnago, M. Benetton, A. Da Ros, G. Borella +6 more
2023HemaSphere0 citations Open access
Semantic Scholar
P398: DEVELOPMENT AND CHARACTERIZATION OF PRECLINICAL IN VIVO MODELS FOR THE IDENTIFICATION AND TESTING OF NEW THERAPEUTIC APPROACHES FOR PEDIATRIC ACUTE MYELOID LEUKEMIA
A. Da Ros, V. Indio, E. Porcù, G. Borella +10 more
2022HemaSphere0 citations Open access
Semantic Scholar
P1398: INSIGHT INTO ACUTE MYELOID LEUKEMIA INDUCED MSC SECRETOME TO REROUTE THE COURSE OF LEUKEMIA BONE MARROW NICHE
G. Borella, A. Da Ros, Giulia Borile, G. Longo +7 more
2022HemaSphere0 citations Open access
Semantic Scholar

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