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R. Keen · SciRah

Researcher profile · Semantic Scholar

R. Keen

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R. Keen — researcher profile on SciRah

h-index: 30
Works: 121
Citations: 2,975

Most-cited papers

Identification of new susceptibility loci for osteoarthritis (arcOGEN): a genome-wide association study
E. Zeggini, K. Panoutsopoulou, L. Southam, N. W. Rayner +72 more
2012The Lancet424 citations Open access
Semantic Scholar
Anatomical distribution of synovitis in knee osteoarthritis and its association with joint effusion assessed on non-enhanced and contrast-enhanced MRI.
F. Roemer, M. Javaid, A. Guermazi, M. Thomas +4 more
2010Osteoarthritis and Cartilage187 citations Open access
Semantic Scholar
Loci for regulation of bone mineral density in men and women identified by genome wide linkage scan: the FAMOS study.
S. Ralston, N. Galwey, Ian Mackay, O. Albagha +13 more
2005Human Molecular Genetics143 citations Open access
Semantic Scholar
Continued Beneficial Effects of Burosumab in Adults with X-Linked Hypophosphatemia: Results from a 24-Week Treatment Continuation Period After a 24-Week Double-Blind Placebo-Controlled Period
A. Portale, T. Carpenter, M. Brandi, K. Briot +26 more
2019Calcified Tissue International140 citations Open access
Semantic Scholar
Insights into the genetic architecture of osteoarthritis from stage 1 of the arcOGEN study
K. Panoutsopoulou, L. Southam, K. Elliott, N. Wrayner +71 more
2010Annals of the Rheumatic Diseases140 citations Open access
Semantic Scholar
Influence of LRP5 Polymorphisms on Normal Variation in BMD
M. Koay, Wo-On Y. Peng, Yun Zhang, Lisa J. Miles +13 more
2004Journal of Bone and Mineral Research137 citations
Semantic Scholar
Burden of osteoporosis and fractures
R. Keen
2003Current Osteoporosis Reports130 citations
Semantic Scholar
Osteoporosis: strategies for prevention and management.
R. Keen
2007Baillière's Best Practice & Research : Clinical Rheumatology107 citations
Semantic Scholar
Early treatment with zoledronic acid prevents bone loss at the hip following acute spinal cord injury
J. Bubbear, A. Gall, F. Middleton, M. Ferguson-Pell +2 more
2010Osteoporosis International88 citations
Semantic Scholar
Molecular Analysis of DMP1 Mutants Causing Autosomal Recessive Hypophosphatemic Rickets
E. Farrow, Siobhan I. Davis, L. Ward, Lelia J. Summers +6 more
2008Bone67 citations Open access
Semantic Scholar
Natural history of fibrodysplasia ossificans progressiva: cross-sectional analysis of annotated baseline phenotypes
R. Pignolo, G. Baujat, Matthew A. Brown, C. De Cunto +9 more
2019Orphanet Journal of Rare Diseases66 citations Open access
Semantic Scholar
Evidence of association and linkage disequilibrium between a novel polymorphism in the transforming growth factor beta 1 gene and hip bone mineral density: a study of female twins.
R. Keen, H. Snieder, H. Molloy, J. Daniels +7 more
2001Rheumatology63 citations
Semantic Scholar
Reduction of New Heterotopic Ossification (HO) in the Open‐Label, Phase 3 MOVE Trial of Palovarotene for Fibrodysplasia Ossificans Progressiva (FOP)
R. Pignolo, Edward C. Hsiao, M. Al Mukaddam, G. Baujat +13 more
2022Journal of Bone and Mineral Research59 citations Open access
Semantic Scholar
Burosumab treatment in adults with X-linked hypophosphataemia: 96-week patient-reported outcomes and ambulatory function from a randomised phase 3 trial and open-label extension
K. Briot, A. Portale, M. Brandi, T. Carpenter +26 more
2021RMD Open55 citations Open access
Semantic Scholar
Dual neutralisation of IL-17F and IL-17A with bimekizumab blocks inflammation-driven osteogenic differentiation of human periosteal cells
M. Shah, A. Maroof, P. Gikas, G. Mittal +4 more
2020RMD Open55 citations Open access
Semantic Scholar
Early clinical observations on the use of imatinib mesylate in FOP: A report of seven cases.
F. Kaplan, Jeffrey R. Andolina, P. Adamson, D. Teachey +8 more
2017Bone47 citations
Semantic Scholar
The natural history of fibrodysplasia ossificans progressiva: A prospective, global 36-month study.
R. Pignolo, G. Baujat, Matthew A. Brown, C. De Cunto +8 more
2022Genetics in Medicine44 citations Open access
Semantic Scholar
Back pain during different sequential treatment regimens of teriparatide: results from EUROFORS
G. Lyritis, F. Marin, C. Barker, M. Pfeifer +5 more
2010Current Medical Research and Opinion44 citations
Semantic Scholar
Palovarotene for Fibrodysplasia Ossificans Progressiva (FOP): Results of a Randomized, Placebo‐Controlled, Double‐Blind Phase 2 Trial
R. Pignolo, G. Baujat, Edward C. Hsiao, R. Keen +5 more
2022Journal of Bone and Mineral Research38 citations Open access
Semantic Scholar
Measurement of abnormal bone composition in vivo using noninvasive Raman spectroscopy
Kevin Buckley, J. Kerns, P. Gikas, H. Birch +5 more
201438 citations Open access
Semantic Scholar
Evidence from Raman Spectroscopy of a Putative Link Between Inherent Bone Matrix Chemistry and Degenerative Joint Disease
J. Kerns, P. Gikas, Kevin Buckley, Adam Shepperd +8 more
2014Arthritis & Rheumatology37 citations Open access
Semantic Scholar
Associations Between Clinical Evidence of Inflammation and Synovitis in Symptomatic Knee Osteoarthritis: A Cross‐Sectional Substudy
G. Wallace, S. Cro, C. Doré, L. King +6 more
2016Arthritis care & research36 citations Open access
Semantic Scholar
Can biochemical markers predict bone loss at the hip and spine?: A 4-year prospective study of 141 early postmenopausal women
R. Keen, T. Nguyen, R. Sobnack, L. Perry +2 more
2005Osteoporosis International35 citations
Semantic Scholar
Benefit of burosumab in adults with X-linked hypophosphataemia (XLH) is maintained with long-term treatment
P. Kamenickỷ, K. Briot, M. Brandi, M. Cohen-Solal +13 more
2023RMD Open33 citations Open access
Semantic Scholar
Special considerations for clinical trials in fibrodysplasia ossificans progressiva (FOP)
Edward C. Hsiao, M. Dirocco, A. Cali, M. Zasloff +18 more
2018British Journal of Clinical Pharmacology32 citations Open access
Semantic Scholar
The FOP Connection Registry: Design of an international patient-sponsored registry for Fibrodysplasia Ossificans Progressiva.
Neal Mantick, Eric S. Bachman, G. Baujat, Matt Brown +22 more
2017Bone27 citations
Semantic Scholar
European women's preference for osteoporosis treatment: influence of clinical effectiveness and dosing frequency*
R. Keen, E. Jódar, G. Iolascon, H. Kruse +3 more
2006Current Medical Research and Opinion27 citations
Semantic Scholar
Self-reported baseline phenotypes from the International Fibrodysplasia Ossificans Progressiva (FOP) Association Global Registry.
R. Pignolo, K. Cheung, Sammi Kile, Mary Anne Fitzpatrick +16 more
2020Bone25 citations
Semantic Scholar
Fibrodysplasia Ossificans Progressiva: What Have We Achieved and Where Are We Now? Follow-up to the 2015 Lorentz Workshop
Ruben D. de Ruiter, Bernard J. Smilde, G. Pals, N. Bravenboer +31 more
2021Frontiers in Endocrinology20 citations Open access
Semantic Scholar
International physician survey on management of FOP: a modified Delphi study
M. Dirocco, G. Baujat, M. Bertamino, Matthew A. Brown +9 more
2017Orphanet Journal of Rare Diseases19 citations Open access
Semantic Scholar
Efficacy of Burosumab in Adults with X-linked Hypophosphatemia (XLH): A Post Hoc Subgroup Analysis of a Randomized Double-Blind Placebo-Controlled Phase 3 Study
M. Brandi, S. Jan de Beur, K. Briot, T. Carpenter +25 more
2022Calcified Tissue International17 citations
Semantic Scholar
The prevalence of musculoskeletal pain and therapy needs in adults with Osteogenesis Imperfecta (OI) a cross-sectional analysis
Sophie Barlow, L. Dove, A. Jaggi, R. Keen +1 more
2022BMC Musculoskeletal Disorders17 citations Open access
Semantic Scholar
Bone mineral density in institutionalised patients with refractory epilepsy.
J. Swanton, R. Simister, D. Altmann, H. Watts +3 more
2007Seizure15 citations Open access
Semantic Scholar
Rare musculoskeletal diseases in adults: a research priority setting partnership with the James Lind Alliance
Gerda Mickute, Kristina Staley, H. Delaney, Oliver Gardiner +14 more
2020Orphanet Journal of Rare Diseases14 citations Open access
Semantic Scholar
Skeletal Manifestations of Osteogenesis Imperfecta
A. Fotiadou, M. Calleja, R. Hargunani, R. Keen
2016Seminars in Musculoskeletal Radiology14 citations
Semantic Scholar
Changes in bone turnover markers during the close season in elite football (soccer) players.
R. Weiler, R. Keen, R. Wolman
2012Journal of Science and Medicine in Sport13 citations
Semantic Scholar
Patients with ACVR1R206H mutations have an increased prevalence of cardiac conduction abnormalities on electrocardiogram in a natural history study of Fibrodysplasia Ossificans Progressiva
S. Kou, C. De Cunto, G. Baujat, Kelly L. Wentworth +10 more
2020Orphanet Journal of Rare Diseases12 citations Open access
Semantic Scholar
Quadriceps traumatic myositis ossificans in a football player: management with intravenous pamidronate.
Siva Mani-Babu, R. Wolman, R. Keen
2014Clinical Journal of Sports Medicine11 citations
Semantic Scholar
Polymorphisms of the vitamin d receptor gene do not predict quantitative ultrasound of the calcaneus or hip axis length
N. Arden, R. Keen, J. Lanchbury, T. D. Spector
2005Osteoporosis International11 citations
Semantic Scholar
A three-generation family with metaphyseal dysplasia, maxillary hypoplasia and brachydactyly (MDMHB) due to intragenic RUNX2 duplication
Amina Al-Yassin, A. Calder, Mike Harrison, T. Lester +5 more
2018European Journal of Human Genetics10 citations Open access
Semantic Scholar
Post-authorisation safety study of burosumab use in paediatric, adolescent and adult patients with X-linked hypophosphataemia: rationale and description
M. Brandi, G. Ariceta, S. Beck-Nielsen, A. Boot +15 more
2022Therapeutic Advances in Chronic Disease9 citations Open access
Semantic Scholar
Correction to: Natural history of fibrodysplasia ossificans progressiva: cross-sectional analysis of annotated baseline phenotypes
R. Pignolo, G. Baujat, Matthew A. Brown, C. De Cunto +9 more
2019Orphanet Journal of Rare Diseases6 citations Open access
Semantic Scholar
236th ENMC International Workshop Bone protective therapy in Duchenne muscular dystrophy: Determining the feasibility and standards of clinical trials Hoofddorp, The Netherlands, 1-3 June 2018.
S. C. Wong, V. Straub, L. Ward, R. Quinlivan +26 more
2019Neuromuscular Disorders5 citations Open access
Semantic Scholar
The current status of Paget's disease of the bone.
R. Keen
2003Hospital Medicine5 citations
Semantic Scholar
Garetosmab Reduces Flare-ups in Patients With Fibrodysplasia Ossificans Progressiva
K. Dahir, J. Mcginniss, S. Mellis, R. Sanchez +25 more
20214 citations Open access
Semantic Scholar
Palovarotene inhibits the development of new heterotopic ossification in fibrodysplasia ossificans progressiva (FOP)
F. Kaplan, Edward C. Hsiao, G. Baujat, R. Keen +6 more
2019Bone Abstracts4 citations
Semantic Scholar
Osteoporosis and Metabolic Bone Disease [127–142] 127. Osteoporosis, Falls and Fractures: Three Confounders in One Equation. Development and Validity of a New form for Assessment of Patients Referred for Dxa Scanning
Y. El Miedany, M. El Gaafary, S. Youssef, M. Toth +62 more
20104 citations
Semantic Scholar
Chondrosarcoma in Association With Primary Hyperparathyroidism
A. Bhatia, S. Cannon, T. Briggs, R. Keen
2004Journal of Bone and Mineral Research4 citations
Semantic Scholar
Usefulness of bone densitometry in postmenopausal women with clinically diagnosed vertebral fractures
K. Moss, R. Keen
2002Annals of the Rheumatic Diseases4 citations Open access
Semantic Scholar
Longitudinal assessment of physical function in adults with X-linked hypophosphatemia following initiation of burosumab therapy
G. Orlando, M. Roy, J. Bubbear, S. Clarke +3 more
2022Osteoporosis International3 citations
Semantic Scholar

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