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L. Dou · SciRah

Researcher profile · Semantic Scholar

L. Dou

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L. Dou — researcher profile on SciRah

h-index: 27
Works: 70
Citations: 3,444

Most-cited papers

Aging and aging-related diseases: from molecular mechanisms to interventions and treatments
Jun Guo, Xiu-Qing Huang, L. Dou, Mingjing Yan +3 more
2022Signal Transduction and Targeted Therapy1,600 citations Open access
Semantic Scholar
Naringin Attenuates High Fat Diet Induced Non-alcoholic Fatty Liver Disease and Gut Bacterial Dysbiosis in Mice
Hong-Na Mu, Qi Zhou, Rui-Yue Yang, Jie Zeng +9 more
2020Frontiers in Microbiology149 citations Open access
Semantic Scholar
Long Noncoding RNA lncSHGL Recruits hnRNPA1 to Suppress Hepatic Gluconeogenesis and Lipogenesis
Junpei Wang, Weili Yang, Zhen-Zhen Chen, Ji Chen +7 more
2018Diabetes101 citations Open access
Semantic Scholar
Dexrazoxane ameliorates doxorubicin-induced cardiotoxicity by inhibiting both apoptosis and necroptosis in cardiomyocytes.
Xiao-Xue Yu, Yang Ruan, Xiu-Qing Huang, L. Dou +13 more
2019Biochemical and Biophysical Research Communications - BBRC96 citations
Semantic Scholar
NFE2 Induces miR-423-5p to Promote Gluconeogenesis and Hyperglycemia by Repressing the Hepatic FAM3A-ATP-Akt Pathway
Weili Yang, Junpei Wang, Zhen-Zhen Chen, Ji Chen +10 more
2017Diabetes91 citations
Semantic Scholar
Ultraconserved element uc.372 drives hepatic lipid accumulation by suppressing miR-195/miR4668 maturation
Jun Guo, Weiwei Fang, Libo Sun, Yonggang Lu +5 more
2018Nature Communications79 citations Open access
Semantic Scholar
Cardiac Aging: From Basic Research to Therapeutics
Mingjing Yan, Shenghui Sun, Kun Xu, Xiu-Qing Huang +5 more
2021Oxidative Medicine and Cellular Longevity77 citations Open access
Semantic Scholar
DDX5 and DDX17—multifaceted proteins in the regulation of tumorigenesis and tumor progression
Kun Xu, Shenghui Sun, Mingjing Yan, Ju Cui +9 more
2022Frontiers in Oncology69 citations Open access
Semantic Scholar
miR-200s Contribute to Interleukin-6 (IL-6)-induced Insulin Resistance in Hepatocytes*
L. Dou, Ting Zhao, Li-Lin Wang, Xiu-Qing Huang +7 more
2013Journal of Biological Chemistry69 citations Open access
Semantic Scholar
SIRT1 Functions as an Important Regulator of Estrogen-Mediated Cardiomyocyte Protection in Angiotensin II-Induced Heart Hypertrophy
Tao Shen, Ling Ding, Yang Ruan, Weiwei Qin +11 more
2014Oxidative Medicine and Cellular Longevity56 citations Open access
Semantic Scholar
Panax Notogingseng Saponins Suppress RAGE/ MAPK Signaling and NF-kappaB Activation in Apolipoprotein-E-deficient Atherosclerosis-prone mice
L. Dou, Yonggang Lu, Tao Shen, Xiu-Qing Huang +3 more
2012Cellular Physiology and Biochemistry56 citations Open access
Semantic Scholar
DEAD-box helicase 17 (DDX17) protects cardiac function by promoting mitochondrial homeostasis in heart failure
Min Yan, Junpeng Gao, M. Lan, Que Wang +23 more
2024Signal Transduction and Targeted Therapy52 citations Open access
Semantic Scholar
Dexrazoxane Protects Cardiomyocyte from Doxorubicin-Induced Apoptosis by Modulating miR-17-5p
Xiao-Xue Yu, Yang Ruan, Tao Shen, Quan Qiu +10 more
2020BioMed Research International49 citations Open access
Semantic Scholar
The antioxidant N-acetylcysteine promotes atherosclerotic plaque stabilization through suppression of RAGE, MMPs and NF-κB in ApoE-deficient mice.
Yonggang Lu, Weiwei Qin, Tao Shen, L. Dou +4 more
2011Journal of atherosclerosis and thrombosis48 citations Open access
Semantic Scholar
Mir-338-3p Mediates Tnf-A-Induced Hepatic Insulin Resistance by Targeting PP4r1 to Regulate PP4 Expression
L. Dou, Shuyue Wang, Libo Sun, Xiu-Qing Huang +6 more
2017Cellular Physiology and Biochemistry46 citations Open access
Semantic Scholar
MicroRNA‐20a‐5p contributes to hepatic glycogen synthesis through targeting p63 to regulate p53 and PTEN expression
Weiwei Fang, Jun Guo, Yuan Cao, Shuyue Wang +7 more
2016Journal of Cellular and Molecular Medicine46 citations Open access
Semantic Scholar
Reduced miR-200b and miR-200c expression contributes to abnormal hepatic lipid accumulation by stimulating JUN expression and activating the transcription of srebp1
Jun Guo, Weiwei Fang, Libo Sun, Yonggang Lu +7 more
2016OncoTarget45 citations Open access
Semantic Scholar
Apigenin alleviates oxidative stress-induced myocardial injury by regulating SIRT1 signaling pathway.
Kun Xu, Yao Yang, M. Lan, Jian-Nan Wang +14 more
2023European Journal of Pharmacology44 citations
Semantic Scholar
MiR-19a regulates PTEN expression to mediate glycogen synthesis in hepatocytes
L. Dou, Xiangyu Meng, Xiao-Fang Sui, Shuyue Wang +7 more
2015Scientific Reports43 citations Open access
Semantic Scholar
Liver MicroRNA-291b-3p Promotes Hepatic Lipogenesis through Negative Regulation of Adenosine 5′-Monophosphate (AMP)-activated Protein Kinase α1*
Xiangyu Meng, Jun Guo, Weiwei Fang, L. Dou +7 more
2016Journal of Biological Chemistry41 citations Open access
Semantic Scholar
Modified citrus pectin inhibits galectin-3 function to reduce atherosclerotic lesions in apoE-deficient mice
Yonggang Lu, Ming-Ming Zhang, Pei Zhao, M. Jia +5 more
2017Molecular Medicine Reports40 citations Open access
Semantic Scholar
MiR-301a Mediates the Effect of IL-6 on the AKT/GSK Pathway and Hepatic Glycogenesis by Regulating PTEN Expression
L. Dou, Shuyue Wang, Xiao-Fang Sui, Xiangyu Meng +7 more
2015Cellular Physiology and Biochemistry38 citations Open access
Semantic Scholar
MiR-291b-3p Induces Apoptosis in Liver Cell Line NCTC1469 by Reducing the Level of RNA-binding Protein HuR
Jun Guo, Meng Li, Xiangyu Meng, Jing-Zhe Sui +6 more
2014Cellular Physiology and Biochemistry37 citations Open access
Semantic Scholar
MicroRNA 152 regulates hepatic glycogenesis by targeting PTEN
Shuyue Wang, Li-Lin Wang, L. Dou, Jun Guo +7 more
2016The FEBS Journal36 citations
Semantic Scholar
miR-23a/b-3p promotes hepatic lipid accumulation by regulating Srebp-1c and Fas.
Lin-Fang Li, Xiao-Yi Zhang, Hangjiang Ren, Xiu-Qing Huang +4 more
2021Journal of Molecular Endocrinology31 citations Open access
Semantic Scholar
Bone marrow macrophage‐derived exosomal miR‐143‐5p contributes to insulin resistance in hepatocytes by repressing MKP5
Lin-Fang Li, Huiyan Zuo, Xiu-Qing Huang, Tao Shen +5 more
2021Cell Proliferation27 citations Open access
Semantic Scholar
miR-154-5p Functions as an Important Regulator of Angiotensin II-Mediated Heart Remodeling
Que Wang, Xiao-Xue Yu, L. Dou, Xiu-Qing Huang +8 more
2019Oxidative Medicine and Cellular Longevity27 citations Open access
Semantic Scholar
Simvastatin Suppresses Apoptosis in Vulnerable Atherosclerotic Plaques Through Regulating the Expression of p53, Bcl-2 and Bcl-xL
Weiwei Qin, Yonggang Lu, Chen Zhan, Tao Shen +6 more
2012Cardiovascular Drugs and Therapy25 citations
Semantic Scholar
NADPH oxidase 2 plays a critical role in dysfunction and apoptosis of pancreatic β-cells induced by very low-density lipoprotein
J. Jiao, L. Dou, Miao Li, Yonggang Lu +4 more
2012Molecular and Cellular Biochemistry24 citations
Semantic Scholar
GPR120 facilitates cholesterol efflux in macrophages through activation of AMPK signaling pathway
Tong An, Xiao-Yi Zhang, Hong-Xia Li, L. Dou +7 more
2020The FEBS Journal21 citations Open access
Semantic Scholar
Hepatic MiR-291b-3p Mediated Glucose Metabolism by Directly Targeting p65 to Upregulate PTEN Expression
Jun Guo, L. Dou, Xiangyu Meng, Zhen-Zhen Chen +7 more
2017Scientific Reports21 citations Open access
Semantic Scholar
MicroRNA-494-3p alleviates inflammatory response in sepsis by targeting TLR6.
H.-R. Wang, Y.-X. Li, Y.-X. Wang, H.-J. Li +1 more
2019European Review for Medical and Pharmacological Sciences20 citations
Semantic Scholar
Lysophosphatidylcholine disrupts cell adhesion and induces anoikis in hepatocytes
Hao Chen, Jia-Rui Ma, Jin Liu, L. Dou +9 more
2022FEBS Letters18 citations
Semantic Scholar
Influences of up-regulation of miR-126 on septic inflammation and prognosis through AKT/Rac1 signaling pathway.
H.-F. Wang, Y.-Q. Wang, L. Dou, H.-M. Gao +3 more
2019European Review for Medical and Pharmacological Sciences16 citations
Semantic Scholar
miR‑338‑3p mediates gluconeogenesis via targeting of PP4R1 in hepatocytes.
Shuyue Wang, Lin-Fang Li, Xie-Hui Chen, Xiu-Qing Huang +9 more
2018Molecular Medicine Reports15 citations Open access
Semantic Scholar
MiR-19a mediates gluconeogenesis by targeting PTEN in hepatocytes.
L. Dou, Shuyue Wang, Xiu-Qing Huang, Xuelin Sun +6 more
2017Molecular Medicine Reports15 citations Open access
Semantic Scholar
Efficient delivery of miR-122 to regulate cholesterol metabolism using a non-covalent peptide-based strategy.
Li-Lin Wang, Wei Tang, Shirong Yan, Long Zhou +6 more
2013Molecular Medicine Reports15 citations Open access
Semantic Scholar
miR-488-3p Protects Cardiomyocytes against Doxorubicin-Induced Cardiotoxicity by Inhibiting CyclinG1
Mingjing Yan, Yuan Cao, Que Wang, Kun Xu +14 more
2022Oxidative Medicine and Cellular Longevity14 citations Open access
Semantic Scholar
Polypeptide Globular Adiponectin Ameliorates Hypoxia/Reoxygenation-Induced Cardiomyocyte Injury by Inhibiting Both Apoptosis and Necroptosis
Kai-Yi Zhu, Jia Guo, Xiao-Xue Yu, Que Wang +11 more
2021Journal of Immunological Research14 citations Open access
Semantic Scholar
Inhibition of Poly(ADP-Ribose) Polymerase Increased Lipid Accumulation Through SREBP1 Modulation
Jing Pang, Ju Cui, Chao Xi, Tao Shen +4 more
2018Cellular Physiology and Biochemistry14 citations Open access
Semantic Scholar
Protein phosphatase 4 plays dual roles during cell proliferation
Xiu-Qing Huang, Jin Liu, Tao Shen, Xiangyu Meng +3 more
2016Cell Proliferation13 citations Open access
Semantic Scholar
Knowledge mapping of exosomes in metabolic diseases: a bibliometric analysis (2007-2022)
Fangzhi Xu, Chenxi Xia, L. Dou, Xiu-Qing Huang
2023Frontiers in Endocrinology11 citations Open access
Semantic Scholar
High glucose reduces hepatic glycogenesis by suppression of microRNA‑152.
Xiaoyun Zhao, Yonggang Lu, Fenghong Wang, L. Dou +3 more
2014Molecular Medicine Reports11 citations Open access
Semantic Scholar
NADPH Oxidase 2-derived Reactive Oxygen Species are Involved in Dysfunction and Apoptosis of Pancreatic β-cells Induced by Low Density Lipoprotein
Miao Li, L. Dou, J. Jiao, Yonggang Lu +4 more
2012Cellular Physiology and Biochemistry11 citations Open access
Semantic Scholar
Phosphoenolpyruvate induces endothelial dysfunction and cell senescence through stimulation of metabolic reprogramming
Tong An, Xiao-Yi Zhang, Xin Gao, Xi-Yue Zhang +8 more
2023Journal of Bioenergetics and Biomembranes10 citations
Semantic Scholar
The dual functions of the pentacyclic triterpenoid madecassic acid in ameliorating doxorubicin-induced cardiotoxicity and enhancing the antitumor efficacy of doxorubicin
Wenlin Li, Kun Xu, M. Lan, Junpeng Gao +16 more
2024International Journal on Biological Sciences9 citations Open access
Semantic Scholar
2, 2-dimethylthiazolidine hydrochloride protects against experimental contrast-induced acute kidney injury via inhibition of tubular ferroptosis.
B. Dai, Qiuyue Su, Xuan Liu, Xue Mi +8 more
2023Biochemical and Biophysical Research Communications - BBRC7 citations
Semantic Scholar
Screening and Evaluation of tRF-Glu-CTC-013 as a Biomarker and Key Regulator in the Development of Cardiac Hypertrophy
Wenlin Li, M. Lan, Kun Xu, Sai-Nan Li +16 more
2025International Journal of Medical Sciences6 citations Open access
Semantic Scholar
A Novel “Endocrine Hormone”: The Diverse Role of Extracellular Vesicles in Multiorgan Insulin Resistance
Fangzhi Xu, L. Dou, Dong Yu, Xi Wu +3 more
2024International Journal of Medical Sciences6 citations Open access
Semantic Scholar
DDX17 protects hepatocytes against oleic acid/palmitic acid-induced lipid accumulation.
Xiao-Yi Zhang, Tong An, Xi-Yue Zhang, Tao Shen +6 more
2022Biochemical and Biophysical Research Communications - BBRC6 citations
Semantic Scholar

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