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Kosuke Otani · SciRah

Researcher profile · Semantic Scholar

Kosuke Otani

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Kosuke Otani — researcher profile on SciRah

h-index: 10
Works: 54
Citations: 315

Most-cited papers

Plasma exosomes regulate systemic blood pressure in rats.
Kosuke Otani, Mai Yokoya, Tomoko Kodama, Kiko Hori +3 more
2018Biochemical and Biophysical Research Communications - BBRC50 citations
Semantic Scholar
Eukaryotic elongation factor 2 kinase controls proliferation and migration of vascular smooth muscle cells
T. Usui, Ryo Nijima, Tomoki Sakatsume, Kosuke Otani +3 more
2015Acta Physiologica33 citations
Semantic Scholar
Chemerin-9-induced contraction was enhanced through the upregulation of smooth muscle chemokine-like receptor 1 in isolated pulmonary artery of pulmonary arterial hypertensive rats
Ayaho Omori, Makoto Goshima, C. Kakuda, Tomoko Kodama +3 more
2020Pflügers Archiv: European Journal of Physiology23 citations
Semantic Scholar
Death-associated protein kinase 3 mediates vascular structural remodelling via stimulating smooth muscle cell proliferation and migration.
T. Usui, Tomoki Sakatsume, Ryo Nijima, Kosuke Otani +5 more
2014Clinical science21 citations
Semantic Scholar
Vasculo-protective effect of BMS-309403 is independent of its specific inhibition of fatty acid-binding protein 4
Yuta Okamura, Kosuke Otani, Akihiro Sekiguchi, Taisuke Kogane +5 more
2017Pflügers Archiv: European Journal of Physiology16 citations
Semantic Scholar
Diverse distribution of tyrosine receptor kinase B isoforms in rat multiple tissues
Kosuke Otani, Muneyoshi Okada, H. Yamawaki
2017Journal of Veterinary Medical Science16 citations Open access
Semantic Scholar
Optimal Isolation Method of Small Extracellular Vesicles from Rat Plasma
Kosuke Otani, Yusei Fujioka, Muneyoshi Okada, H. Yamawaki
2019International Journal of Molecular Sciences15 citations Open access
Semantic Scholar
Chemerin-9 stimulates migration in rat cardiac fibroblasts in vitro.
Atsunori Yamamoto, Ayumi Sagara, Kosuke Otani, Muneyoshi Okada +1 more
2021European Journal of Pharmacology14 citations Open access
Semantic Scholar
Human omentin-1 reduces vascular insulin resistance and hypertension in Otsuka Long-Evans Tokushima Fatty rats
Yuta Okamura, Ko Adachi, R. Niijima, Tomoko Kodama +3 more
2023Naunyn-Schmiedeberg's Archives of Pharmacology12 citations
Semantic Scholar
Cardiovascular Characteristics of Zucker Fatty Diabetes Mellitus Rats, an Animal Model for Obesity and Type 2 Diabetes
Kosuke Otani, H. Funada, Risa Teranishi, Muneyoshi Okada +1 more
2022International Journal of Molecular Sciences11 citations Open access
Semantic Scholar
Development of an Effective Isolation Method for Plasma Extracellular Vesicles Excluding Lipoproteins by Precipitation With Polyethylene Glycol
Kosuke Otani, Yusei Fujioka, Muneyoshi Okada, H. Yamawaki
2025Journal of Extracellular Biology10 citations Open access
Semantic Scholar
Eukaryotic elongation factor 2 kinase inhibitor, A484954 induces diuretic effect via renal vasorelaxation in spontaneously hypertensive rats.
Tomoko Kodama, S. Kameshima, Kosuke Otani, Muneyoshi Okada +1 more
2021European Journal of Pharmacology10 citations Open access
Semantic Scholar
Expression pattern and function of tyrosine receptor kinase B isoforms in rat mesenteric arterial smooth muscle cells.
Kosuke Otani, Muneyoshi Okada, H. Yamawaki
2015Biochemical and Biophysical Research Communications - BBRC10 citations
Semantic Scholar
Preventive Effect of Canstatin against Ventricular Arrhythmia Induced by Ischemia/Reperfusion Injury: A Pilot Study
A. Sugiyama, Yurie Shimizu, Muneyoshi Okada, Kosuke Otani +1 more
2021International Journal of Molecular Sciences9 citations Open access
Semantic Scholar
Chemokine-like Receptor 1 in Brain of Spontaneously Hypertensive Rats Mediates Systemic Hypertension
Atsunori Yamamoto, Kosuke Otani, Muneyoshi Okada, H. Yamawaki
2021International Journal of Molecular Sciences9 citations Open access
Semantic Scholar
Autocrine role of senescent cardiac fibroblasts-derived extracellular vesicles
Yusei Fujioka, Kosuke Otani, Tomoko Kodama, Muneyoshi Okada +1 more
2023Journal of Veterinary Medical Science7 citations Open access
Semantic Scholar
Human Omentin-1 Administration Ameliorates Hypertensive Complications without Affecting Hypertension in Spontaneously Hypertensive Rats
Yuta Okamura, R. Niijima, S. Kameshima, Tomoko Kodama +3 more
2023International Journal of Molecular Sciences6 citations Open access
Semantic Scholar
Eukaryotic elongation factor 2 kinase inhibitor, A484954 inhibits perivascular sympathetic nerve stimulation-induced vasoconstriction in isolated renal artery.
Tomoko Kodama, Kosuke Otani, Muneyoshi Okada, H. Yamawaki
2022European Journal of Pharmacology5 citations Open access
Semantic Scholar
Decreased Expression of Canstatin in Rat Model of Monocrotaline-Induced Pulmonary Arterial Hypertension: Protective Effect of Canstatin on Right Ventricular Remodeling
A. Sugiyama, Maina Kaisho, Muneyoshi Okada, Kosuke Otani +1 more
2020International Journal of Molecular Sciences5 citations Open access
Semantic Scholar
[Development of basic research toward clinical application of cleaved fragment of type IV collagen].
A. Sugiyama, Muneyoshi Okada, Kosuke Otani, H. Yamawaki
2021Nihon yakurigaku zasshi. Folia pharmacologica Japonica4 citations
Semantic Scholar
Small extracellular vesicles from rat plasma promote migration and proliferation of vascular smooth muscle cells
Kosuke Otani, Mai Yokoya, Yusei Fujioka, Muneyoshi Okada +1 more
2020Journal of Veterinary Medical Science4 citations Open access
Semantic Scholar
Age-dependent increase in activity of eukaryotic elongation factor 2 kinase in mesenteric arteries from spontaneously hypertensive rats
Tomoko Kodama, Kosuke Otani, Muneyoshi Okada, H. Yamawaki
2020Journal of Veterinary Medical Science4 citations Open access
Semantic Scholar
Senescent cardiac fibroblasts-derived extracellular vesicles induced autophagy in cardiac fibroblasts via suppression of ras homolog enriched in brain like 1.
Yusei Fujioka, Kosuke Otani, Muneyoshi Okada, H. Yamawaki
2025Journal of Pharmacological Sciences3 citations Open access
Semantic Scholar
Eukaryotic elongation factor 2 kinase inhibitor, A484954 induced diuresis via nitric oxide production in spontaneously hypertensive rats
Tomoko Kodama, Kosuke Otani, Muneyoshi Okada, H. Yamawaki
2023Journal of Veterinary Medical Science3 citations Open access
Semantic Scholar
A single injection of periostin decreases cardiac voltage-gated Na+ channel in rat ventricles
Keisuke Imoto, Yuho Sakai, Muneyoshi Okada, Kosuke Otani +1 more
2021Journal of Veterinary Medical Science3 citations Open access
Semantic Scholar
Plasma small extracellular vesicles in hypertensive rats impair reactivity of isolated blood vessels
Yusei Fujioka, Kosuke Otani, Muneyoshi Okada, H. Yamawaki
2020Journal of Veterinary Medical Science3 citations Open access
Semantic Scholar
The eukaryotic elongation factor 2 kinase inhibitor, A484954, induces hypoglycaemic and hypotensive effects
Tomoko Kodama, S. Kameshima, Kosuke Otani, Muneyoshi Okada +1 more
2025British Journal of Pharmacology2 citations
Semantic Scholar
Alteration of reactivity in isolated mesenteric artery from Zucker fatty diabetes mellitus rats.
Kosuke Otani, Naofumi Uemura, H. Funada, Tomoko Kodama +2 more
2024Journal of Pharmacological Sciences2 citations Open access
Semantic Scholar
Minocycline prevents monocrotaline-induced pulmonary hypertension through the attenuation of endothelial dysfunction and vascular wall thickening.
R. Niijima, Kosuke Otani, Tomoko Kodama, Muneyoshi Okada +1 more
2024Journal of Pharmacological Sciences2 citations Open access
Semantic Scholar
Vasculo-protective effect of BMS-309403 is independent of its specific inhibition of fatty acid-binding protein 4
Yuta Okamura, Kosuke Otani, Akihiro Sekiguchi, Taisuke Kogane +5 more
2017Pflügers Archiv: European Journal of Physiology2 citations
Semantic Scholar
A selective eukaryotic elongation factor 2 kinase inhibitor, A484954 lowered blood glucose in Zucker fatty diabetes mellitus rat.
Ko Adachi, Tomoko Kodama, Kosuke Otani, Keito Sano +3 more
2025Journal of Pharmacological Sciences1 citations Open access
Semantic Scholar
Minocycline inhibits endothelin-1-induced contraction in isolated pulmonary artery.
R. Niijima, Kosuke Otani, T. Kodama, Yusei Fujioka +2 more
2026Journal of Pharmacological Sciences0 citations Open access
Semantic Scholar
Protective function of the voltage-gated potassium channel Kv11.3 in a mouse model of cardiac ischemia/reperfusion injury
Hayato Sasaki, Kazuki Otake, Kazuki Takeda, Karin Tesaki +10 more
2025PLoS ONE0 citations Open access
Semantic Scholar
Isolation of plasma extracellular vesicles excluding lipoproteins by using polyanion and a divalent cation
Kosuke Otani, Tomoko Kodama, Muneyoshi Okada, H. Yamawaki
2023Proceedings for Annual Meeting of The Japanese Pharmacological Society0 citations Open access
Semantic Scholar
Migratory and proliferative effects of arresten in rat cardiac fibroblasts
Tomoki Kobayashi, Muneyoshi Okada, Tomoko Kodama, Kosuke Otani +1 more
2023Proceedings for Annual Meeting of The Japanese Pharmacological Society0 citations Open access
Semantic Scholar
Effects of cellular senescence on secretion of extracellular vesicles in neonatal rat cardiac fibroblasts
Yusei Fujioka, Kosuke Otani, M. Sugiyama, Muneyoshi Okada +1 more
2022Proceedings for Annual Meeting of The Japanese Pharmacological Society0 citations Open access
Semantic Scholar
Cardiovascular dynamics of Zucker Fatty Diabetes Mellitus (ZFDM) rats, an animal model of obesity and diabetes
Kosuke Otani, Risa Teranishi, H. Funada, Muneyoshi Okada +1 more
2022Proceedings for Annual Meeting of The Japanese Pharmacological Society0 citations Open access
Semantic Scholar
The alteration of contractile reactivity in isolated mesenteric arteries from Zucker fatty diabetes mellitus rats
H. Funada, Kosuke Otani, Tomoko Kodama, Muneyoshi Okada +1 more
2022Proceedings for Annual Meeting of The Japanese Pharmacological Society0 citations Open access
Semantic Scholar
Effects of N-terminal fragment of canstatin on left ventricular hypertrophy in a rat model of angiotensin II-induced hypertension
Masanari Mori, A. Sugiyama, Muneyoshi Okada, Kosuke Otani +1 more
2022Proceedings for Annual Meeting of The Japanese Pharmacological Society0 citations Open access
Semantic Scholar
Chemerin fragments show different effects on systemic blood pressure dependent on carboxyl-terminal cleavage site
Atsunori Yamamoto, Tomoko Kodama, Kosuke Otani, Muneyoshi Okada +1 more
2022Journal of Veterinary Medical Science0 citations Open access
Semantic Scholar
Acute intracerebroventricular injection of an eEF2K inhibitor lowers systemic blood pressure in hypertensive rats
Atsunori Yamamoto, On Uezawa, Tomoko Kodama, Kosuke Otani +2 more
2022Proceedings for Annual Meeting of The Japanese Pharmacological Society0 citations Open access
Semantic Scholar
Expression and function of basement membrane-derived matricryptins in thickening of mitral valve in rats
Muneyoshi Okada, Kota Sano, Ryunosuke Suzuki, Tomoko Kodama +2 more
2022Proceedings for Annual Meeting of The Japanese Pharmacological Society0 citations Open access
Semantic Scholar
Expression of arresten and its role in the heart of rats with angiotensin II-induced hypertension
Muneyoshi Okada, Syuya Kurihara, Masanari Mori, Kosuke Otani +1 more
2022Proceedings for Annual Meeting of The Japanese Pharmacological Society0 citations Open access
Semantic Scholar
Relationship between plasma extracellular vesicles (EV) and systemic blood pressure in Otsuka Long-Evans Tokushima Fatty (OLETF) rats
Risa Teranishi, Kosuke Otani, Muneyoshi Okada, H. Yamawaki
2021Proceedings for Annual Meeting of The Japanese Pharmacological Society0 citations Open access
Semantic Scholar
The alteration of molecular properties in plasma extracellular vesicles from spontaneously hypertensive rats
Kosuke Otani, Muneyoshi Okada, H. Yamawaki
2021Proceedings for Annual Meeting of The Japanese Pharmacological Society0 citations Open access
Semantic Scholar
Chemerin/CMKLR1 in the brain of spontaneously hypertensive rats mediates systemic hypertension
Atsunori Yamamoto, Naoko Yamaguchi, S. Okada, Kosuke Otani +2 more
2021Proceedings for Annual Meeting of The Japanese Pharmacological Society0 citations Open access
Semantic Scholar
Eukaryotic elongation factor 2 kinase inhibitor, A484954 induces diuretic effect in spontaneously hypertensive rats
Tomoko Kodama, Kosuke Otani, Muneyoshi Okada, H. Yamawaki
2021Proceedings for Annual Meeting of The Japanese Pharmacological Society0 citations Open access
Semantic Scholar
Arresten, a cleaved fragment of type IV collagen α1 chain, regulates functions of cardiac fibroblasts and left atria
A. Sugiyama, S. Tajima, Riki Yamamoto, Kosuke Otani +2 more
2021Proceedings for Annual Meeting of The Japanese Pharmacological Society0 citations Open access
Semantic Scholar
Age-dependent change in size distribution of plasma sEV from Wistar rat
Yusei Fujioka, Kosuke Otani, Muneyoshi Okada, H. Yamawaki
2020Proceedings for Annual Meeting of The Japanese Pharmacological Society0 citations Open access
Semantic Scholar
Effects of exosomes derived from organs of spontaneously hypertensive rats on reactivity of thoracic aorta from normotensive Wistar rats
Yusei Fujioka, Kosuke Otani, Muneyoshi Okada, H. Yamawaki
2019Proceedings for Annual Meeting of The Japanese Pharmacological Society0 citations Open access
Semantic Scholar

Frequent co-authors

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Muneyoshi Okada×50
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Muneyoshi Okada — researcher profile on SciRah
H. Yamawaki×49
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H. Yamawaki — researcher profile on SciRah
Tomoko Kodama×22
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Tomoko Kodama — researcher profile on SciRah
Yusei Fujioka×10
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Yusei Fujioka — researcher profile on SciRah

×5

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S. Kameshima — researcher profile on SciRah

Atsunori Yamamoto×5

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Atsunori Yamamoto — researcher profile on SciRah

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A. Sugiyama — researcher profile on SciRah

Yuta Okamura×4

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Yuta Okamura — researcher profile on SciRah

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R. Niijima — researcher profile on SciRah

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H. Funada — researcher profile on SciRah

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C. Kakuda — researcher profile on SciRah

Risa Teranishi×3

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Risa Teranishi — researcher profile on SciRah