Skip to content

Home Search Authors Pakistan News Saved

SciRah

SciRah does not host or store research papers. Results come live from free, official scholarly APIs, and every paper links back to its original source.

Data sources

OpenAlex
Semantic Scholar
Crossref
CORE
arXiv
PubMed

Privacy policy Terms of service

Svetlana L. Avlasevich · SciRah

Researcher profile · Semantic Scholar

Svetlana L. Avlasevich

Share profile

Svetlana L. Avlasevich — researcher profile on SciRah

h-index: 22
Works: 61
Citations: 1,691

Most-cited papers

In vitro micronucleus assay scored by flow cytometry provides a comprehensive evaluation of cytogenetic damage and cytotoxicity.
S. Bryce, J. Bemis, Svetlana L. Avlasevich, S. Dertinger
2007Mutation research196 citations Open access
Semantic Scholar
In vitro micronucleus scoring by flow cytometry: Differential staining of micronuclei versus apoptotic and necrotic chromatin enhances assay reliability
Svetlana L. Avlasevich, S. Bryce, Siân E. Cairns, S. Dertinger
2006Environmental and Molecular Mutagenesis146 citations
Semantic Scholar
When Pigs Fly: Immunomagnetic separation facilitates rapid determination of Pig-a mutant frequency by flow cytometric analysis
S. Dertinger, S. Bryce, S. Phonethepswath, Svetlana L. Avlasevich
2011Mutation research103 citations Open access
Semantic Scholar
Efficient monitoring of in vivo pig-a gene mutation and chromosomal damage: summary of 7 published studies and results from 11 new reference compounds.
S. Dertinger, S. Phonethepswath, Svetlana L. Avlasevich, D. Torous +6 more
2012Toxicological Sciences91 citations Open access
Semantic Scholar
Integration of mutation and chromosomal damage endpoints into 28-day repeat dose toxicology studies.
S. Dertinger, S. Phonethepswath, D. Franklin, Pamela Weller +7 more
2010Toxicological Sciences91 citations Open access
Semantic Scholar
Interlaboratory evaluation of a flow cytometric, high content in vitro micronucleus assay.
S. Bryce, Svetlana L. Avlasevich, J. Bemis, Magdalena Lukamowicz +11 more
2008Mutation research88 citations Open access
Semantic Scholar
Pig-a mutation: kinetics in rat erythrocytes following exposure to five prototypical mutagens.
S. Phonethepswath, D. Franklin, D. Torous, S. Bryce +8 more
2010Toxicological Sciences84 citations Open access
Semantic Scholar
Three‐color labeling method for flow cytometric measurement of cytogenetic damage in rodent and human blood
S. Dertinger, K. Camphausen, J. T. Macgregor, Michelle E. Bishop +12 more
2004Environmental and Molecular Mutagenesis79 citations
Semantic Scholar
Assessment of genotoxicity associated with hydroxyurea therapy in children with sickle cell anemia
Jonathan M. Flanagan, T. Howard, N. Mortier, Svetlana L. Avlasevich +4 more
2009Mutation research62 citations Open access
Semantic Scholar
Miniaturized Flow Cytometric In Vitro Micronucleus Assay Represents an Efficient Tool for Comprehensively Characterizing Genotoxicity Dose-Response Relationships
S. Bryce, Svetlana L. Avlasevich, J. Bemis, S. Phonethepswath +1 more
2010Mutation research60 citations Open access
Semantic Scholar
Flow cytometric analysis of micronuclei in mammalian cell cultures: past, present and future.
Svetlana L. Avlasevich, S. Bryce, M. De Boeck, A. Elhajouji +5 more
2011Mutagenesis56 citations Open access
Semantic Scholar
High Content Flow Cytometric Micronucleus Scoring Method is Applicable to Attachment Cell Lines
S. Bryce, Jing Shi, J. Nicolette, Marilyn S. Diehl +5 more
2009Environmental and Molecular Mutagenesis51 citations Open access
Semantic Scholar
Interlaboratory Pig‐a gene mutation assay trial: Studies of 1,3‐propane sultone with immunomagnetic enrichment of mutant erythrocytes
S. Dertinger, S. Phonethepswath, Pamela Weller, Svetlana L. Avlasevich +8 more
2011Environmental and Molecular Mutagenesis49 citations
Semantic Scholar
Human Erythrocyte PIG-A Assay: An Easily Monitored Index of Gene Mutation Requiring Low Volume Blood Samples
S. Dertinger, Svetlana L. Avlasevich, J. Bemis, Yuhchyau Chen +1 more
2014Environmental and Molecular Mutagenesis45 citations Open access
Semantic Scholar
Miniaturized flow cytometry‐based CHO‐K1 micronucleus assay discriminates aneugenic and clastogenic modes of action
S. Bryce, Svetlana L. Avlasevich, J. Bemis, S. Dertinger
2011Environmental and Molecular Mutagenesis45 citations
Semantic Scholar
Automated human blood micronucleated reticulocyte measurements for rapid assessment of chromosomal damage.
S. Dertinger, Richard K. Miller, K. Brewer, T. Smudzin +6 more
2007Mutation research42 citations Open access
Semantic Scholar
Persistence of cisplatin-induced mutagenicity in hematopoietic stem cells: implications for secondary cancer risk following chemotherapy.
S. Dertinger, Svetlana L. Avlasevich, D. Torous, J. Bemis +7 more
2014Toxicological Sciences38 citations Open access
Semantic Scholar
Flow cytometric 96‐well microplate‐based in vitro micronucleus assay with human TK6 cells: Protocol optimization and transferability assessment
S. Bryce, Svetlana L. Avlasevich, J. Bemis, Matthew Tate +8 more
2013Environmental and Molecular Mutagenesis38 citations
Semantic Scholar
Excision of mutagenic replication-blocking lesions suppresses cancer but promotes cytotoxicity and lethality in nitrosamine-exposed mice
Jennifer E. Kay, J. Corrigan, Amanda L Armijo, Ilana S Nazari +11 more
2020bioRxiv34 citations Open access
Semantic Scholar
Mouse Pig‐a and micronucleus assays respond to N‐ethyl‐N‐nitrosourea, benzo[a]pyrene, and ethyl carbamate, but not pyrene or methyl carbamate
Carson Labash, Svetlana L. Avlasevich, Kristine Carlson, Ariel Berg +5 more
2016Environmental and Molecular Mutagenesis25 citations
Semantic Scholar
Rat Pig-a mutation assay responds to the genotoxic carcinogen ethyl carbamate but not the non-genotoxic carcinogen methyl carbamate.
J. Bemis, Carson Labash, Svetlana L. Avlasevich, Kristine Carlson +5 more
2015Mutagenesis24 citations Open access
Semantic Scholar
Pig‐a gene mutation and micronucleated reticulocyte induction in rats exposed to tumorigenic doses of the leukemogenic agents chlorambucil, thiotepa, melphalan, and 1,3‐propane sultone
S. Dertinger, S. Phonethepswath, Svetlana L. Avlasevich, D. Torous +4 more
2014Environmental and Molecular Mutagenesis24 citations
Semantic Scholar
3Rs Friendly Study Designs Facilitate Rat Liver and Blood Micronucleus Assays and Pig-a Gene Mutation Assessments: Proof-of-Concept with 13 Reference Chemicals
S. Dertinger, Svetlana L. Avlasevich, D. Torous, Priyanka Singh +5 more
2019Environmental and Molecular Mutagenesis22 citations Open access
Semantic Scholar
In vivo flow cytometric Pig‐a and micronucleus assays: Highly sensitive discrimination of the carcinogen/noncarcinogen pair benzo(a)pyrene and pyrene using acute and repeated‐dose designs
D. Torous, S. Phonethepswath, Svetlana L. Avlasevich, Jared A. Mereness +8 more
2012Environmental and Molecular Mutagenesis20 citations
Semantic Scholar
Human blood PIG-A mutation and micronucleated reticulocyte flow cytometric assays: Method optimization and evaluation of intra- and inter-subject variation
D. Torous, Svetlana L. Avlasevich, Mona Khattab, A. Baig +7 more
2020Environmental and Molecular Mutagenesis16 citations Open access
Semantic Scholar
Glycosylphosphatidylinositol (GPI) Anchored Protein Deficiency Serves as a Reliable Reporter of Pig-a Gene Mutation—Support from an In vitro Assay Based on L5178Y/Tk+/− Cells and the CD90.2 Antigen
J. Bemis, Svetlana L. Avlasevich, Carson Labash, P. McKinzie +3 more
2017Environmental and Molecular Mutagenesis16 citations Open access
Semantic Scholar
Comparison of male versus female responses in the Pig-a mutation assay.
Carson Labash, Svetlana L. Avlasevich, Kristine Carlson, D. Torous +4 more
2015Mutagenesis16 citations Open access
Semantic Scholar
Diethylnitrosamine genotoxicity evaluated in sprague dawley rats using Pig‐a mutation and reticulocyte micronucleus assays
Svetlana L. Avlasevich, S. Phonethepswath, Carson Labash, Kristine Carlson +5 more
2014Environmental and Molecular Mutagenesis15 citations
Semantic Scholar
Integration of liver and blood micronucleus and Pig-a gene mutation endpoints into rat 28-day repeat-treatment studies: Proof-of-principle with diethylnitrosamine
Sumee Khanal, Priyanka Singh, Svetlana L. Avlasevich, D. Torous +2 more
2018Mutation Research. Genetic Toxicology and Environmental Mutagenesis14 citations Open access
Semantic Scholar
Diet-induced obesity increases the frequency of Pig-a mutant erythrocytes in male C57BL/6J mice
Jeffrey K. Wickliffe, S. Dertinger, D. Torous, Svetlana L. Avlasevich +2 more
2016Environmental and Molecular Mutagenesis14 citations Open access
Semantic Scholar
Flow cytometric method for scoring rat liver micronuclei with simultaneous assessments of hepatocyte proliferation
Svetlana L. Avlasevich, Sumee Khanal, Priyanka Singh, D. Torous +2 more
2018Environmental and Molecular Mutagenesis11 citations Open access
Semantic Scholar
Flow cytometric analysis of Pig‐a gene mutation and chromosomal damage induced by procarbazine hydrochloride in CD‐1 mice
S. Phonethepswath, Svetlana L. Avlasevich, D. Torous, Jared A. Mereness +3 more
2013Environmental and Molecular Mutagenesis10 citations
Semantic Scholar
Induction of Pig-a mutant erythrocytes in male and female rats exposed to 1,3-propane sultone, ethyl carbamate, or thiotepa
Carson Labash, Kristine Carlson, Svetlana L. Avlasevich, Ariel Berg +3 more
2015Mutation Research. Genetic Toxicology and Environmental Mutagenesis9 citations Open access
Semantic Scholar
Visualization Strategies to Aid Interpretation of High-Dimensional Genotoxicity Data
S. Dertinger, Erica Briggs, Yusuf Hussien, S. Bryce +5 more
2024Environmental and Molecular Mutagenesis8 citations Open access
Semantic Scholar
Lack of hydroxyurea‐associated mutagenesis in pediatric sickle cell disease patients
D. Torous, Svetlana L. Avlasevich, J. Bemis, T. Howard +6 more
2023Environmental and Molecular Mutagenesis8 citations
Semantic Scholar
Assessment of systemic genetic damage in pediatric inflammatory bowel disease
A. Baig, Svetlana L. Avlasevich, D. Torous, J. Bemis +4 more
2020Environmental and Molecular Mutagenesis8 citations Open access
Semantic Scholar
In vivo Pig-a and micronucleus study of the prototypical aneugen vinblastine sulfate
Svetlana L. Avlasevich, Carson Labash, D. Torous, J. Bemis +2 more
2017Environmental and Molecular Mutagenesis7 citations Open access
Semantic Scholar
Biomarkers of DNA Damage Response Improves In Vitro Micronucleus Assays by Revealing Genotoxic Mode of Action and Reducing the Occurrence of Irrelevant Positive Results.
Svetlana L. Avlasevich, Tina Pellegrin, Manali J. Godse, S. Bryce +3 more
2021Mutagenesis6 citations Open access
Semantic Scholar
Suitability of Long‐Term Frozen Rat Blood Samples for the Interrogation of Pig‐a Gene Mutation by Flow Cytometry
Svetlana L. Avlasevich, D. Torous, J. Bemis, J. Bhalli +10 more
2018Environmental and Molecular Mutagenesis5 citations
Semantic Scholar
Sex and Alkyladenine DNA Glycosylase Expression are Key Susceptibility Factors for NDMA-induced Mutations, Toxicity, and Cancer
Jennifer E. Kay, J. Corrigan, Lindsay B. Volk, Amanda L. Armijo +9 more
2025bioRxiv3 citations Open access
Semantic Scholar
Intra‐ and inter‐laboratory reproducibility of the rat blood Pig‐a gene mutation assay
S. Dertinger, Svetlana L. Avlasevich, D. Torous, J. Bemis +4 more
2020Environmental and Molecular Mutagenesis3 citations
Semantic Scholar
Application of biological modifiers to a multiplexed, human cell-based DNA damage assay provides mechanistic information on genotoxicity and molecular targets
S. Bryce, Svetlana L. Avlasevich, Adam Conrad, Nikki E. Hall +4 more
2025Environmental and Molecular Mutagenesis2 citations Open access
Semantic Scholar
Persistent interferon signaling and clonal expansion mark early events in DNA methylation damage-induced liver cancer
Lee J. Pribyl, Jennifer E. Kay, J. Corrigan, Lindsay B. Volk +20 more
2025bioRxiv2 citations
Semantic Scholar
Cyclophosphamide and etoposide canine studies demonstrate the cross-species potential of the flow cytometric peripheral blood micronucleated reticulocyte endpoint.
M. Mckeon, Yong Xu, D. Kirkland, G. Schmuck +3 more
2012Mutation research2 citations
Semantic Scholar
Mitigation of volatile chemicals’ effect on adjacent microtiter plate wells
Svetlana L. Avlasevich, Erica Briggs, Kyle Tichenor, Adam Conrad +4 more
2025Environmental and Molecular Mutagenesis1 citations Open access
Semantic Scholar
Dextran sulfate sodium mouse model of inflammatory bowel disease evaluated for systemic genotoxicity via blood micronucleus and Pig-a gene mutation assays.
Christopher Kirby, A. Baig, Svetlana L. Avlasevich, D. Torous +5 more
2020Mutagenesis1 citations Open access
Semantic Scholar
Integration of cII and Pig-a mutation and micronucleus endpoints into the Big Blue® transgenic mouse mutation assay: Results for benzo(a)pyrene (BaP) and n-ethyl-n-nitrosourea (ENU)
R. Young, H. Dinesdurage, David Bruning, L. Stankowski +8 more
20141 citations
Semantic Scholar
Abstract 3149: Micronuclei (MN) dynamics in preclinical models and in patient reticulocytes as a pharmacodynamic biomarker for the first in class DNA polymerase theta (PolΘ) inhibitor ART6043
Colette L. Baxter, T. Yap, S. Ulahannan, N. Lakhani +17 more
2026Cancer Research0 citations
Semantic Scholar
Persistent interferon signaling and clonal expansion mark early events in DNA methylation damage-induced liver cancer
Lee J. Pribyl, Jennifer E. Kay, J. Corrigan, Lindsay B. Volk +20 more
2026NAR Cancer0 citations Open access
Semantic Scholar
Abstract 3148: Human blood micronucleated reticulocytes: Application as a pharmacodynamic biomarker for DNA double strand breaks in oncology drug development
J. Bemis, Colette L. Baxter, G. Langford, T. Yap +8 more
2026Cancer Research0 citations
Semantic Scholar

Frequent co-authors

Invite them to SciRah by sharing their profile.

S. Dertinger×49
Invite
S. Dertinger — researcher profile on SciRah
J. Bemis×37
Invite
J. Bemis — researcher profile on SciRah
D. Torous×32
Invite
D. Torous — researcher profile on SciRah
S. Bryce×20
Invite
S. Bryce — researcher profile on SciRah

J. T. Macgregor

×20

Invite

J. T. Macgregor — researcher profile on SciRah

S. Phonethepswath×11

Invite

S. Phonethepswath — researcher profile on SciRah

Carson Labash×8

Invite

Carson Labash — researcher profile on SciRah

Jared A. Mereness×6

Invite

Jared A. Mereness — researcher profile on SciRah

Kristine Carlson×6

Invite

Kristine Carlson — researcher profile on SciRah

Pamela Weller×5

Invite

Pamela Weller — researcher profile on SciRah

Yuhchyau Chen×5

Invite

Yuhchyau Chen — researcher profile on SciRah

A. Elhajouji×4

Invite

A. Elhajouji — researcher profile on SciRah