Cyberknife® system: a new therapeutic strategy for sinonasal solitary extramedullary plasmacytomae.
Elena Cantonea, Valentina Borzillob, Antonella Miriam Di Lulloa, Luana Maranoc, Elia Guadagnod e, Gelsomina Mansuetod e, Rossella Di Francob, Francesca Cammarotab, Lucio Catalanoc, Paolo Mutob, Maurizio Iengoa
- aDepartment of Neuroscience, ENT Section; “Federico II” University of Naples, Italy
- bDivision of Radiotherapy, Istituto Nazionale Tumori Fondazione Pascale, Naples, Italy
- cDepartment of Hematology; “Federico II” University of Naples, Italy
- dDepartment of Advanced Biomedical Sciences, Pathology Section; “Federico II” University of Naples, Italy
- eDepartment of Advanced Biomedical Sciences- Pathology Section, Federico II University of Naples, Italy
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Abstract
Sino-nasal solitary extramedullary plasmacytoma (EMP) is a rare neoplasm with unpredictable progression to multiple myeloma. To improve the precision of irradiation delivery, preserving the healthy surrounding tissue and critical structures we used a CyberKnife® for the treatment of sinonasal solitary extramedullary plasmacytoma. We present the first case of sinonasal-EMP treated with CyberKnife®-stereotactic radiotherapy (SRT) with a complete remission without adverse events. Based on the post-therapeutic results and healthy tissue preservation, we believe that CyberKnife®-SRT represents a good therapeutic option for the treatment of sinonasal-EMP.