A new diagnostic approach to the Dubin-Johnson syndrome.
T Pinósa, Constansa Jm, Antonio Palacı́n, Concepción Figueras
- aDepartment of Gastroenterology, Quinta de Salud La Aliança, Sabadell, Spain
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Abstract
Dubin-Johnson syndrome (DJS), a congenital metabolic disorder of bilirubin excretion, was classically diagnosed by the bromsulfalein (BSP) curve and needle hepatic biopsy methods. We present three cases of DJS and propose a new diagnostic approach which could conceivably become a substitute for more aggressive techniques. The results of the 24-h urine coproporphyrin determination and 99mTc-Disofenin scintigraphy gave, together, enough data for an accurate diagnosis.
TL;DRA new diagnostic approach is proposed which could conceivably become a substitute for more aggressive techniques in DJS and the results of the 24-h urine coproporphyrin determination and 99mTc-Disofenin scintigraphy gave enough data for an accurate diagnosis. (Semantic Scholar)