Clinical trial comparing two daytime hydrogen-peroxide professional vital-bleaching systems.
J. Perdigãoa, C. anauatE-nEttob, A. R. Carmob, H. Lewgoyb, H. J. D. Cordeirob, M. DUTRA-CORREAb, N. Castilhosb, R. Amoreb
- aDivision of Operative Dentistry, Department of Restorative Sciences, University of Minnesota, Minneapolis, MN, USA
- bUniversity of Minnesota‐Twin Cities
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Abstract
A randomized clinical trial was conducted to compare the whitening effectiveness and tolerability of two daytime, professional, hydrogen-peroxide, vital-bleaching systems. Adults who had never bleached their teeth were randomly assigned to use either 14% hydrogen-peroxide whitening strips or a marketed 9.5% hydrogen-peroxide custom-tray-based system. Maxillary arch treatment was twice daily for 30 minutes for 9 to 21 days, depending on the labeled instructions for use. Whitening response was measured objectively as L*a*b* (which represent three-dimensional tooth color from light to dark, green to red, and blue to yellow, respectively) from digital images of the maxillary anterior teeth, while comparative at-home tolerability was assessed from bleaching tolerability severity days (BTSD) scores. A total of 31 participants aged 18 to 64 were evaluated. At the end of treatment, the adjusted mean (standard deviation [SD]) delta b* was -3.35 (0.37) for the strips and -1.67 (0.344) for the trays. Treatments differed significantly (P < .05) with respect to delta b*, as well as to delta L* and delta W* values at the end of treatment. Overall, at-home strip use was better tolerated, especially with respect to oral irritation. BTSD means (SD) were 0.09 (0.25) and 0.38 (0.49), with treatments differing significantly (P = .036), favoring the strips. This comparative research demonstrated that at the end of treatment, the 14% hydrogen-peroxide whitening strips resulted in a superior, twofold reduction in yellowness and better in-use tolerability compared to the 9.5% hydrogen-peroxide custom-tray system.
TL;DRThe 6-month retention rate of the self etch dentin adhesive system Clearfil SE Bond was not improved by enamel beveling or by ename etching, suggesting instrumentation or etching of enamel may not be critical for its clinical performance at 6 months. (Semantic Scholar)

