Studies on anti-folate antimalarials in east Africa.
F. Ortellia b, C. Maxwell, J. Curtis, W. Watkins
- aLondon School of Hygiene and Tropical Medicine, UK
- bLondon School of Hygiene & Tropical Medicine, UK
Papers open inside SciRah from the original publisher or repository; SciRah never hosts them.
Abstract
Chlorproguanil-dapsone (CD) appears to be a promising anti-folate combination (Amukoye et al., 1997) to substitute for pyrimethamine-sulfadoxine (PS), which has a long half-life and against which there is resistance in several Plasmodium falciparum populations including the highly endemic lowland area near Muheza, Tanzania (Trigg et al., 1997).
TL;DRChlorproguanil-dapsone appears to be a promising anti-folate combination to substitute for pyrimethamine-sulfadoxine (PS), which has a long half-life and against which there is resistance in several Plasmodium falciparum populations including the highly endemic lowland area near Muheza, Tanzania. (Semantic Scholar)