Sustainable Synthesis of Functional Nanomaterials for Environmental and Biomedical Applications
Bassam M. Abualsouda, Abdul Waheed Ghanghrob, Uzair Ahmadc, Aminad, Muhammad Razzaqe, Akhtar Alif, Shoaib Shafiqueg
- aDepartment of Pharmaceutics and Pharmaceutical Technology, College of Pharmacy, Al-Ahliyya Amman University, Amman, Jordan
- bInstitute of Biochemistry, university of Sindh, Jamshoro, Pakistan
- cInstitute of chemical sciences, Bahauddin Zakariya University Multan, Pakistan
- dDepartment of Physics, Bacha Khan University Charsadda, Pakistan
- eDepartment of Biotechnology and Genetic, Engineering Kohat, University of Science and Technology, Kohat, KP, Pakistan
- fNational Centre of Excellent in Analytical Chemistry University of Sindh, Jamshoro, Pakistan
- gSchool of Biochemistry and Biotechnology, University of the Punjab Lahore, Pakistan
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Abstract
In the current experiment, green synthesis of AgNPs and ZnO nanoparticles was done by making use of an aqueous solution extracted from the leaves of Azadirachta indica. Nanoparticles were synthesized successfully through the green method, and their formation was evident through visible color changes and precipitation. Surface plasmon resonance peak was measured through UV-visible spectroscopy to be 432 nm, indicating successful and efficient synthesis of nanoparticles with good stability and uniformity. Functional groups present were O-H, C=O, C-N, and C-O, implying that some phytochemical compounds present in plants were utilized in the reduction process. High crystallinity of AgNPs and ZnO NPs was evident through XRD pattern results, which show a face-centered cubic structure and a hexagonal wurtzite structure of crystallite sizes ranging between 15-35 nm. The fabricated nanomaterials displayed good antibacterial behavior towards Staphylococcus aureus and Escherichia coli, whereby silver nanoparticles had better antimicrobial behavior compared to other fabricated nanomaterials. Better antibacterial behavior was due to the small size of nanoparticles, increased surface area, and good interaction with the membrane of bacteria cells. Generally, the results show that fabricated nanomaterials have promising properties for biomedical and environmental uses.
TL;DRThe fabricated nanomaterials displayed good antibacterial behavior towards Staphylococcus aureus and Escherichia coli, whereby silver nanoparticles had better antimicrobial behavior compared to other fabricated nanomaterials. (Semantic Scholar)

