Comparison between Pre-Operative Fine Needle Aspiration Cytology and Post-Operative Histopathology Report of Solitary Thyroid Nodule

Objective: To compare preoperative fine needle aspiration cytology (FNAC) with postoperative histopathology report of solitary thyroid nodules. Place and Duration of Study: Department of General Surgery, Combined Military Hospital, Rawalpindi Pakistan, from Aug, 2020 to Mar, 2021. Methodology: In this study, total 42 patients including male and female were enrolled. Thyroid functioning tests of every patient was performed and all of them were found to be euthyroid. Patients were divided into different categories of age groups. Fine needle aspiration cytology and ultrasonography were used as a tools preoperatively to determine the procedure that was to be performed and it was followed by post-operative histopathological examination. Results: Thyroid lesions were found to be more common in females than males; 35(83.81%) females and 7(16.7%) males. FNAC report depicted 36(85.71%) benign lesions and 7(14.28%) malignant lesions. Histopathological sampling was performed in which 33(78.57%) benign lesions and 9(21.42%) malignant lesions were diagnosed. Conclusion: For diagnosis of thyroid nodules FNAC is considered as safe and simple but false negativity was observed so histopathological examination was considered as confirmatory tool for diagnosis.