The Gut Microbiome: Unveiling its Potential Role in Dementia Risk
Asia Filatova b c d✉
- aThe University of Chicago , 5841 S. Maryland Avenue , Chicago IL 60637 , Illinois , USA
- bThe University of Chicago , Illinois , USA
- cThe University of Chicago
- dThe University of Chicago, 5841 S. Maryland Avenue, Chicago IL 60637, Illinois, USA
- ✉Corresponding author
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Abstract
Dementia is a prevalent neurodegenerative disorder characterized by cognitive decline and functional impairment. The gut microbiome, a complex ecosystem of microorganisms residing in the gastrointestinal tract, has emerged as a potential contributor to dementia risk. This paper presents a comprehensive review of the existing literature, analyzing 20 relevant studies to explore the role of the gut microbiome in dementia risk. The findings highlight the potential mechanisms underlying this association and discuss potential therapeutic interventions. The results suggest that the gut microbiome may play a significant role in modulating brain health and cognitive function, providing new avenues for understanding and managing dementia.

