A Short Review: Divulge on Growth Heritage of Biochemically Isolated Adipose-Derived Mesenchymal Stem Cells, Types, Risks, and Therapeutics Roles
Amber Khana, Muhammad Abubakarb c, Hafiza Malaika Arifd, Abdul Salamd, Saleem Awana, Areeb Anwar Usmania, Rooma Ayyoubb c, Assad Ullahb c
- aDepartment of Biosciences University of Shaheed Zulfiqar Ali Bhutto Institute of Science and Technology (SZABIST) Karachi
- bBiosciences Department , COMSATS University Islamabad
- cBiosciences Department, COMSATS University Islamabad
- dDow International Medical College Karachi
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Abstract
Tissue engineering and regenerative medicine’s progression and benefits are based on harvesting healthy stem cells for their remarkable therapeutic effects. In context with tissue rehabilitation and repair, stem cells are a key vehicle for cellular therapies. This review paper aims to report a protocol for the isolation of a homogenous population of murine Adipose-derived Mesenchymal Stem cells (mAd-MSCs) their identification, growth characteristics, proliferation, types, risk factors as well as their therapeutic roles. Various assays are discussed here to check the properties, proliferation, and differentiation of ad-MSCs. Ad-MSCs are found to be associated with angiogenesis, regenerative abilities (wound healing and tissue repairing), suppressing the immune system during autoimmune disorders, cardiovascular illness, cartilage repair, and potential therapeutic cellular carriers for targeted and specific drug delivery particularly in the treatment of cancer. Hence, ad-MSCs due to their vast purposes could be utilized to achieve therapeutic goals in the field of medicine
TL;DRA protocol for the isolation of a homogenous population of murine Adipose-derived Mesenchymal Stem cells (mAd-MSCs) their identification, growth characteristics, proliferation, types, risk factors as well as their therapeutic roles are reported. (Semantic Scholar)