Association of Vitamin D Deficiency in Newly Diagnosed Pulmonary Tuberculosis
Khalil Ullaha b, S. ur Rehmanc d, Ramsha Nadeema b, M. Abubakarb, Q. Razae f
- aMedical Specialist , Khyber Teaching Hospital , Peshawar
- bMedical Specialist, Khyber Teaching Hospital, Peshawar
- cPulmonology deptt. , Khyber Teaching Hospital , Peshawar 3
- dPulmonology deptt., Khyber Teaching Hospital, Peshawar 3
- ePGR , KEMU/Mayo Hospital , Lahore
- fPGR, KEMU/Mayo Hospital, Lahore
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Abstract
Aim: Relationship between Vitamin D deficiency and pulmonary tuberculosis. Methodology: Study duration: November 2020 to April 2021 Sampling technique: A case-control study Setting: Hayatabad Medical Complex, Peshawar It included 30 adult newly identified sputum-quality pulmonary tuberculosis patients and 30 age and sex matched healthy cases as controls. All cases had undergone a thorough medical examination and repeated laboratory tests, including vitamin D, calcium, and sputum for AFB and X-ray chest. Results: Majority were males (88%). In the Study group, BMI decreased significantly i.e. 19.0 vs 23.5. Serum vitamin D concentrations were significantly lower in the tuberculosis group i.e. 17.9ng/dl than in the control group 24.8ng/dl. Mean of serum albumin in the control group was 3.9 ng/dl whereas 2.9 ng/dl in the study group. Conclusion: Hypovitaminosis D was associated with more severe medical symptoms, increased sputum smear positivity and large lesions on chest radiographs in patients with pulmonary tuberculosis. Keywords: Vitamin D, Pulmonary Tuberculosis, Sputum
TL;DRHypovitaminosis D was associated with more severe medical symptoms, increased sputum smear positivity and large lesions on chest radiographs in patients with pulmonary tuberculosis. (Semantic Scholar)