Cornea donation process and tissue quality for transplantation
Giovanna Karinny Pereira Cruza✉, Marcos Antônio Ferreira Júniorb, Oleci Pereira Frotab, Élen Ferraz Testonc, Viviane Euzébia Pereira Santosd, Allyne Fortes Vítord, Mayk Penze Cardosoc, Fábio Rogério Rodrigues Leocates de Moraesc
- aHealth Technical School, Federal University of Paraíba, João Pessoa, Paraíba, Brazil
- bNursing Department, Health and Development in The Midwest Region, Federal University of Mato Grosso do Sul, Campo Grande, Mato Grosso do Sul, Brazil
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Abstract
INTRODUCTION: The quality of the corneal tissue can be influenced by several factors inherent to the recipient, donor, and to the donation and transplantation process. The donated corneal tissue can be classified by its quality as excellent, good, regular, bad, or unacceptable for transplantation, evaluating it in a slit lamp. OBJECTIVE: To analyze the relationship between the clinical and sociodemographic variables of the donors and the donation process and the classification of the quality of the corneal tissue collected for transplantation. METHODS: This is an epidemiologic study, retrospective cohort type, which addressed the process of cornea donation by the Human Eye Tissue Bank in a reference service in Northeast Brazil. The sample consisted of corneas processed by the Human Eye Tissue Bank of Rio Grande do Norte (n = 419). For descriptive and inferential analysis, the study used the Statistical Package for the Social Sciences (SPSS) software, version 25.0, and considered a significance level of 0.05. Logistic regression analysis was used for the adjustment of the final model. RESULTS: It was verified that the epidemiological profile showed a prevalence of individuals with a mean age of 42.54 years old, male (73.99%), and living in the metropolitan region of the state capital (75.66%). When analyzing the relationship between the clinical and sociodemographic variables of the donors, it was identified that those aged 45 years old or less had better quality corneas (excellent and good), while the chronological variables were predictive factors for corneas of regular and bad qualities. CONCLUSION: The identification of the factors inherent to the donation process and predictors of corneal tissue quality contribute to minimizing the risk of transplantation and to a better ocular prognosis.
TL;DRThis is an epidemiologic study, retrospective cohort type, which addressed the process of cornea donation by the Human Eye Tissue Bank in a reference service in Northeast Brazil and identified those aged 45 years old or less had better quality corneas, while the chronological variables were predictive factors for cornea of regular and bad qualities. (Semantic Scholar)