Canadian best practice recommendations for the management of amyotrophic lateral sclerosis
Christen L. Shoesmitha b c d e f g h i j k l m n, Agessandro Abrahãoa b c d e f g i j k l m n, Tim J Bensteada b c d e f g i j k l m n, Marvin Chuma b c d e f g i j k l m n, Nicolas Dupréa b c d e f g i j k l m n, Aaron Izenberga b c d e f g i j k l m n, Wendy S. W. Johnstona b c d e f g i j k l m n, Sanjay Kalraa b c d e f g i j k l m n, Desmond J. Leddina b c d e f g i j k l m n, Colleen M. O’Connella b c d e f g i j k l m n o, Kerri Lynn Schellenberga b c d e f g i j k l m n, Anu Tandona b c d e f g i j k l m n, Lorne H. Zinmana b c d e f g i j k l m n
- aLondon Health Sciences Centre (Shoesmith), London, Ont.
- bSunnybrook Health Sciences Centre (Abrahao, Izenberg, Tandon, Zinman), Toronto, Ont.
- cDalhousie University (Benstead, Leddin), Halifax, NS
- dMcMaster University (Chum), Hamilton, Ont.
- eCHU de Québec-Université Laval (Dupre), Québec, Que.
- fUniversity of Alberta (Johnston, Kalra), Edmonton, Alta.
- gStan Cassidy Centre for Rehabilitation (O'Connell), Fredericton, NB
- hUniversity of Saskatchewan (Schellenberg), Saskatoon, Sask. Christen.Shoesmith@lhsc.on.ca
- iCHU de Québec-Université Laval (Dupre), Québec, Que
- jLondon Health Sciences Centre (Shoesmith), London, Ont
- kMcMaster University (Chum), Hamilton, Ont
- lSunnybrook Health Sciences Centre (Abrahao, Izenberg, Tandon, Zinman), Toronto, Ont
- m
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Abstract
KEY POINTS Amyotrophic lateral sclerosis (ALS) is a debilitating, progressive disease with degeneration of motor neurons in the brain and spinal cord causing weakness, muscle atrophy, fasciculations and spasticity.[1][1] Onset in the limbs, with extremity weakness and impairment in mobility, is the
TL;DRAmyotrophic lateral sclerosis is a debilitating, progressive disease with degeneration of motor neurons in the brain and spinal cord causing weakness, muscle atrophy, fasciculations and spasticity. (Semantic Scholar)

