Effect of ferric-carboxy Maltose on Oxygen Kinetics and Functional Status in Heart Failure Patients With Iron Deficiency
S. Dhoota, S. Mittala, S. Singha b c, Vishal Patelb c, R. Kasliwala, Varshil Mehtab c
- aDepartment of Cardiology, Dedanta, The Medicity Hospital, Gurgaon, India
- bChelsea &
- cWestminster Hospital NHS Foundation Trust, West Middlesex University Hospital Site, Isleworth, UK
Papers open inside SciRah from the original publisher or repository; SciRah never hosts them.
Abstract
There is a very high prevalence of iron deficiency anemia in patients with systolic heart failure. The present study is a prospective, parallel, 1:1 randomized controlled trial of intravenous ferric-carboxy maltose compared with standard of care in patients with heart failure. A total of 70 patients who presented to us with symptomatic chronic heart failure were included and randomly assigned to either groups (35 per group). Post 12 weeks, there were improvements noticed in peak VO2, New York Heart Association functional classification, 6-min walk test distance covered and reduction in Minnesota Living with Heart Failure Questionnaire score in the ferric-carboxy maltose as compared with standard of care group. However, no improvement in ejection fraction was noticed.
TL;DRThere were improvements noticed in peak VO2, New York Heart Association functional classification, 6-min walk test distance covered and reduction in Minnesota Living with Heart Failure Questionnaire score in the ferric-carboxy maltose as compared with standard of care group, however, no improvement in ejection fraction was noticed. (Semantic Scholar)