Epidemiologic Profile of Patients Transplanted With Hematopoietic Stem Cells in a Reference Service in the State of Rio Grande do Norte, Brazil
Isabelle Campos de Azevedoa b✉, M.A. Ferreira Júniorc, L.A. Pereira de Aquinob, A.A. de Oliveirab, Giovanna Karinny Pereira Cruzb, Andréia Insabralde de Queiróz Cardosoc, Maria Lúcia Ivoc, Viviane Euzébia Pereira Santosb
- aNursing Department, Federal University of Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil. Electronic address: isabellebr2511@gmail.com
- bNursing Department, Federal University of Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil
- cNursing Department, Federal University of Mato Grosso do Sul, Campo Grande, Mato Grosso do Sul, Brazil
- ✉Corresponding author
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Abstract
Background: Hematopoietic stem cell transplantation (HSCT) consists of the intravenous infusion of healthy hematopoietic stem cells to restore the medullary and immunologic function of patients affected by a series of hematologic, oncologic, immunologic, malignant and nonmalignant inherited or acquired diseases, with the possibility of cure or increase of disease-free survival. Objective: To characterize the epidemiologic profile and the cases of death of patients who underwent HSCT. Methods: This is a cohort quantitative study, nested with a retrospective, descriptive, and analytical study of a hospital-based cohort that included the patients who underwent HSCT at a referral service in the state of Rio Grande do Norte, a region of northeastern Brazil. Results: There was a slight male prevalence (52.94%), the age of the patients ranged from 2 to 73 years old, 18.38% were brown, 47.06% were married, 15.07% were students, 78.31% had a diagnosis of multiple myeloma, 93.38% developed gastrointestinal toxicities, all patients received chemotherapeutic treatment, 54.78% had allogeneic HSCT, and the cause of the most recorded deaths was septic shock (48.19%). Conclusions: This study showed relevant scientific evidence on the clinical and epidemiologic profile of patients who underwent HSCT. In general, sociodemographic data are similar to national and international research results.