Evaluation of antibiotic susceptibility in wound infections: A pilot study from Bangladesh
Sushmita Roya b, Mejbah Uddin Ahmeda b, Bhuiyan Mohammad Mahtab Uddina b, Zubair Ahmed Ratanc d, Monali Rajawate f, Varshil Mehtag h, Sojib Bin Zamani j✉
- aDepartment of Microbiology, Enam Medical College, Savar, Dhaka, Bangladesh
- bDepartment of Microbiology, Enam Medical College, Savar, Dhaka
- cDepartment of Biomedical Engineering, Khulna University of Engineering and Technology, Khulna, Bangladesh
- dDepartment of Biomedical Engineering, Khulna University of Engineering and Technology, Khulna
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Abstract
Introduction : Infections due to antibiotic resistant bacteria have increased alarmingly in both developed and developing countries. Unrestrained and rapidly spreading bacterial growth has turned the management of wound infections into a serious challenge. This study aimed to determine the prevalence of different bacterial pathogens and their antibiotic susceptibility in various types of wound infections. Methods : A cross-sectional study was conducted to collect 105 wound swabs. All isolated bacteria were identified based on colony characteristics, gram stain and standard biochemical tests, and antibiotic susceptibility testing (AST) with the disc diffusion method. Descriptive statistics were used to present the study findings, and all analyses were performed using Stata Version 13. Results : The rate of isolation of bacteria was 92.3%. Staphylococcus aureus was found to be the most frequent isolate (55.7%), followed by Escherichia coli (23.7%), Pseudomonas spp. (8.2%), and Streptococcus pyogenes (7.2%). Gram-positive bacteria were mostly (60%) found sensitive to vancomycin, azithromycin, gentamicin, imipenem, cefixime, and ceftriaxone in this study. Among the Gram-negative bacteria, Escherichia coli (>60%) showed sensitivity to cefixime, azithromycin, cefuroxime, ceftriaxone, cefotaxime, gentamycin, and ceftazidime. Conclusions : The diversity of isolated bacteria and their susceptibility patterns signify a need to implement a proper infection control strategy, which can be achieved by carrying out antibiotic sensitivity tests of the isolates.
TL;DRThe diversity of isolated bacteria and their susceptibility patterns signify a need to implement a proper infection control strategy, which can be achieved by carrying out antibiotic sensitivity tests of the isolates. (Semantic Scholar)