Elemental analysis of the thyroid by laser induced breakdown spectroscopy
Irfan Ahmeda b, Rafay Ahmedb, Jingwei Yangb, Alan Wing Lun Lawb, Yanpeng Zhangc, Condon Laub
- aDepartment of Electrical Engineering, Sukkur IBA University, Sukkur 65200, Pakistan
- bDepartment of Physics, City University of Hong Kong, Hong Kong SAR, China
- cKey Laboratory for Physical Electronics and Devices of the Ministry of Education & Shaanxi Key Lab of Information Photonic Technique, Xi'an Jiaotong University, Xi'an 710049, China
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Abstract
The thyroid is an important hormone regulation organ. Laser induced breakdown spectroscopy (LIBS) is developed to assess iodine and other essential elements in the thyroid (of rats). Subjects are administered 0.05% iodine water for 0, 6, and 12 days before the thyroid is extracted. Pronounced iodine, sodium, calcium, and potassium emissions are observed at approximately 746, 589, 395/422, and 766/770 nm, respectively. Iodine emission is surprisingly highest in 0 day subjects, lowest after 6 days, and recovers by 12 days. This follows the Wolff-Chaikoff effect as ingestion of excess iodine reduces thyroid iodine and iodine is essential for hormone production. LIBS is a promising method for trace elemental analysis of the thyroid.
TL;DRLIBS is a promising method for trace elemental analysis of the thyroid and follows the Wolff-Chaikoff effect as ingestion of excess iodine reduces thyroid iodine and iodine is essential for hormone production. (Semantic Scholar)