The combined use of NPWT and instillation using an octenidine based wound rinsing solution: a case study
Johannes Matiaseka b c, Gabriel Djedovicb d e, Monika Mattesichb f, Evi Maria Morandib f, Reinhard Pauzenbergerb f, Rajmond Pikulab f, Ralph Verstappenb f, G. Piererb f, Rupert Kollera g, Ulrich Michael Riegerb d e
- aDepartment of Plastic, Aesthetic and Reconstructive Surgery, Wilhelminenspital, Vienna, Austria
- bDepartment of Plastic, Reconstructive and Aesthetic Surgery, Innsbruck Medical University, Austria
- c1Department of Plastic, Aesthetic and Reconstructive Surgery, Wilhelminenspital, Vienna, Austria2Department of Plastic, Reconstructive and Aesthetic Surgery, Innsbruck Medical University, Austria
- dDepartment of Plastic and Aesthetic Surgery, Reconstructive & Hand Surgery, St. Markus Hospital, Frankfurt, Germany
- e2Department of Plastic, Reconstructive and Aesthetic Surgery, Innsbruck Medical University, Austria3Department of Plastic and Aesthetic Surgery, Reconstructive & Hand Surgery, St. Markus Hospital, Frankfurt, Germany
- f2Department of Plastic, Reconstructive and Aesthetic Surgery, Innsbruck Medical University, Austria
- g1Department of Plastic, Aesthetic and Reconstructive Surgery, Wilhelminenspital, Vienna, Austria
Papers open inside SciRah from the original publisher or repository; SciRah never hosts them.
Abstract
Effective wound bed preparation is an essential element in the healing of chronic wounds, including pressure ulcers (PUs). Negative pressure wound therapy (NPWT) reduces oedema, stimulates the formation of granulation tissue and helps remove wound exudate. This helps prepare the wound bed for secondary healing, skin grafting or coverage with flaps. Combining NPWT with an instillation phase using an antiseptic (octenidine based) irrigation solution is a novel approach to PU management. Three patients with Category 4 gluteal PUs were treated with NPWT and instillation fluid, following surgical debridement of necrotic tissue. The aim was to achieve optimal wound bed preparation prior to wound closure by local fasciocutaneous flap. The antiseptic efficacy of octenilin wound irrigation solution in microorganism eradication was quantified by in vitro tests simulating real conditions using leg ulcer vacuum exudates. All wounds completely healed after four weeks, and no adverse incidents occurred due to instillation of octenidine. No recurrence of the PU occurred during a one year follow-up.
TL;DRThe aim was to achieve optimal wound bed preparation prior to wound closure by local fasciocutaneous flap, and the antiseptic efficacy of octenilin wound irrigation solution in microorganism eradication was quantified by in vitro tests simulating real conditions using leg ulcer vacuum exudates. (Semantic Scholar)