Dengue--How Best to Classify It
Anon Srikiatkhachorna b, Alan L. Rothmanc, Robert V. Gibbonsd, Nopporn Sittisombute, Prida Malasitf, Francis A. Ennisg h, Suchitra Nimmannityai, S. Kalayanarooji
- aDepartment of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA. anon.srikiatkhachorn@umassmed.edu
- bDepartment of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, 01655, USA
- cInstitute for Immunology and Informatics, University of Rhode Island, Providence, Rhode Island
- dDepartment of Virology, Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand
- eDepartment of Microbiology, Faculty of Medicine, Chiang Mai University, Chiangmai, Thailand
- fMedical Molecular Biology Unit, Siriraj Hopital, Mahidol University, Bangkok, Thailand
- gDepartment of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts
- hDepartment of Medicine University of Massachusetts Medical School, Worcester, Massachusetts
- iQueen Sirikit National Institute of Child Health, Bangkok, Thailand
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Abstract
Dengue has emerged as a major public health problem worldwide. Dengue virus infection causes a wide range of clinical manifestations. Since the 1970s, clinical dengue has been classified according to the World Health Organization guideline as dengue fever and dengue hemorrhagic fever. The classification has been criticized with regard to its usefulness and its applicability. In 2009, the World Health Organization issued a new guideline that classifies clinical dengue as dengue and severe dengue. The 2009 classification differs significantly from the previous classification in both conceptual and practical levels. The impacts of the new classification on clinical practice, dengue research, and public health policy are discussed.
TL;DRThe impacts of the new classification on clinical practice, dengue research, and public health policy are discussed. (Semantic Scholar)

