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Complete Nucleotide Sequence Analysis of a Western Pacific Dengue-1 Virus Strain

Beena Puri^{a b}, William M. Nelson^{b c}, Kevin R. Porter^{b c}, Erik A. Henchal^{d e}, Curtis G. Hayes^{b c}

^aInfectious Diseases Department, Naval Medical Research Institute, Bethesda, Maryland 20889-5607, USA. PURI@NMRIPO.NMRI.NNMC.NAVY.MIL
^bInfectious Diseases Department, Naval Medical Research Institute, Bethesda, Maryland
^cInfectious Diseases Department, Naval Medical Research Institute, Bethesda, Maryland, 20889-5607
^dVirology Division, US Army Medical Research Institute of Infectious Diseases, Fort Detrick, Fredrick, Maryland, 21702-5011
^eVirology Division, US Army Medical Research Institute of Infectious Diseases, Fort Detrick, Fredrick, Maryland

Virus Genes Springer Science+Business Media1998-07-01 14 citations5 references

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Abstract

We have determined the complete nucleotide sequence and the deduced amino acid polypeptide sequence of the genome of a dengue-1 (DEN-1) virus strain isolated from a patient on Nauru in the Western Pacific in 1974 (West Pac 74). The complete genome is 10,735 nucleotides in length and contains a single long open reading frame of 10,176 nucleotides encoding a polyprotein of 3392 amino acids. When compared to DEN-1 Singapore S275/90, the nucleotide and amino acid sequence homology are 94% and 97.8%, respectively.

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Complete Nucleotide Sequence Analysis of a Western Pacific Dengue-1 Virus Strain

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