Dengue Haemorrhagic Fever in Cuba. II. Clinical investigations
María G. Guzmána, Gustavo Kouría, J Bravoa, Maritza Solera, Susana Vázquez, Marianila Santosb, Rinaldo Villaescusab, Paulino Basanta Oterob, Gloria Indan, J.M. Ballesterb
- a“Pedro Kourí” Institute of Tropical Medicine, Havana, Cuba
- bNational Institute of Immunology and Haematology, Havana, Cuba
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Abstract
Clinical and serological studies were carried out on 114 patients admitted to hospital in Havana, Cuba with Dengue Haemorrhagic Fever and Dengue Shock Syndrome (DHF/DSS). Serological confirmation of dengue was obtained in 90% of cases, with 5% of cases primary and 95% secondary. Fever, haemorrhagic manifestations, vomiting and headache were the most frequent signs and symptoms. Among haemorrhagic manifestations, petechiae and vaginal bleeding were reported in a larger number of patients. 21 patients presented shock and, of these, 20 were secondary infections. The disease appeared more frequently in white persons and in women. The aetiopathogenicity of the syndromes is discussed. 95% of the cases could be explained on the basis of the secondary infection hypothesis.
TL;DRClinical and serological studies were carried out on 114 patients admitted to hospital in Havana, Cuba with Dengue Haemorrhagic Fever and Dengue Shock Syndrome, finding 95% of the cases could be explained on the basis of the secondary infection hypothesis. (Semantic Scholar)