Magnitude of the Disease Burden from Neurocysticercosis in a Developing Country
Caryn Berna b, Hector Hugo Garciac, Carlton A. Evansd e, Armando Emiliano Gonzalezf, Manuela Verásteguic, Victor C. W. Tsangg, Robert H. Gilmanc h
- aDivision of Parasitic Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30341, USA. cxb9@cdc.gov
- bDivision of Parasitic Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, 30341, USA
- cUniversidad Cayetano Heredia, Universidad Nacional Mayor de San Marcos, Lima, Peru
- dUniversity of Cambridge Clinical School
- eCambridge United Kingdom
- fFacultad de Medicina Veterinaria, Universidad Nacional Mayor de San Marcos. Lima,#R##N#Perú
- gDivision of Parasitic Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia
- hJohns Hopkins University School of Hygiene and Public Health, Baltimore, Maryland
Papers open inside SciRah from the original publisher or repository; SciRah never hosts them.
Abstract
Cysticercosis contributes to higher epilepsy rates in developing countries than in industrialized ones, yet no estimate exists for the associated burden of disease. We used epidemiological data on neurocysticercosis in Peru to calculate the burden of disease and applied our model to the other countries of Latin America where neurocysticercosis is endemic to determine a regional estimate. Analysis of 12 population-based community studies demonstrated that neurocysticercosis was endemic in highland areas and high jungles, with seroprevalences from 6% to 24%. In one community, the adult seizure disorder rate was 9.1% among seropositive persons versus 4. 6% among seronegative persons; we used this difference for estimates. On the basis of average prevalence rates in areas of endemicity of 6%-10%, we estimated that there are 23,512-39,186 symptomatic neurocysticercosis cases in Peru. In Latin America, an estimated 75 million persons live in areas where cysticercosis is endemic, and approximately 400,000 have symptomatic disease. Cysticercosis contributes substantially to neurological disease in Peru and in all of Latin America.
TL;DRIt is estimated that there are 23,512–39,186 symptomatic neurocysticercosis cases in Peru and in all of Latin America, and Cysticercosis contributes substantially to neurological disease in Peru and in all of Latin America. (Semantic Scholar)