DENGUE AND DENGUE HEMORRHAGIC FEVER IN LATIN AMERICA AND THE CARIBBEAN
Raúl Istúriza b c d e, Duane J. Gublerb c d e f, José Brea del Castillob c d e f
- aDepartamento de Medicina, Centro Médico de Caracas, Venezuela. ul3@bichat.inserm.fr
- bDepartamento de Medicina, Centro Médico de Caracas, and Centro Médico Docente La Trinidad, Caracas, Venezuela
- cDepartamento de Pediatría, Centro Médico, Universidad del Este, Santo Domingo, República Dominicana (JBdC)
- dDivision of Vector-Borne Infectious Diseases, National Center for Infectious Disease, Centers for Disease Control and Prevention, Public Health Service, US Department of Health and Human Services, Fort Collins, Colorado (DJG)
- ethe Département de Médecine Interne, Groupe Hôpitalier Bichat-Claude Bernard, Paris, France (REI)
- fDepartamento de Medicina, Centro Médico de Caracas, and Centro Médico Docente La Trinidad, Caracas, Venezuela; and the Département de Médecine Interne, Groupe Hôpitalier Bichat-Claude Bernard, Paris, France (REI)
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Abstract
Four serotypes of dengue viruses produce dengue fever, dengue hemorrhagic fever, and dengue shock syndrome. They are the most important arbovirus infections of humans, in terms of both morbidity and mortality, constituting one of the most rapidly expanding and re-emerging infectious disease problems in Latin America. In less than 20 years, the region has transformed itself from hypoendemic to hyperendemic, while serotype circulation in most countries has gone from none or single to multiple. Changes in endemicity have coincided with the emergence and increasing incidence of the severer forms of dengue infection. This article reviews the clinical presentations of these diseases. Health care providers who see patients in or returning from areas of Latin America, the Caribbean, and other tropical areas must consider dengue in the differential diagnosis of patients presenting with compatible symptoms, and must be knowledgeable in the current management of this important disease.
TL;DRHealth care providers who see patients in or returning from areas of Latin America, the Caribbean, and other tropical areas must consider dengue in the differential diagnosis of patients presenting with compatible symptoms, and must be knowledgeable in the current management of this important disease. (Semantic Scholar)