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MicroRNAs – targeting and target prediction

^aDepartment of Cancer Research and Molecular Medicine, Norwegian University of Science and Technology, NO-7489 Trondheim, Norway
^bDepartment of Computer and Information Science, Norwegian University of Science and Technology, NO-7491 Trondheim, Norway
✉Corresponding author

New Biotechnology Elsevier BV2010-02-27 146 citations79 references

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Abstract

MicroRNAs (miRNAs) are a class of small noncoding RNAs that can regulate many genes by base pairing to sites in mRNAs. The functionality of miRNAs overlaps that of short interfering RNAs (siRNAs), and many features of miRNA targeting have been revealed experimentally by studying miRNA-mimicking siRNAs. This review outlines the features associated with animal miRNA targeting and describes currently available prediction tools.

TL;DRThe features associated with animal miRNA targeting are outlined and currently available prediction tools are described. (Semantic Scholar)

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MicroRNAs – targeting and target prediction

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