Mayaro Virus Disease: An Emerging Mosquito‐Borne Zoonosis in Tropical South America
Robert B. Tesha b c✉, Douglas M. Wattsb c d, Kevin L. Russellb c d, Chitra Damodaranb c d, Carlos Calampab c d, César Cabezasb c d, Gladys Ramírezb c d, Bruno Vasquezb c d, Curtis G. Hayesb c d, Cynthia A. Rossib c d, Ann M. Powersb c d, Christine L. Hiceb c d, Laura J. Chandlerb c d, Bruce C. Croppb c d, Nick Karabatsosb c d, John T. Roehrigb c d, Duane J. Gublerb c d
- aDepartment of Pathology, Center for Tropical Diseases, University of Texas Medical Branch, Galveston, USA. rtesh@utmb.edu
- bFrom the Department of Pathology, Center for Tropical Diseases, University of Texas Medical Branch, Galveston, Texas, the Division of Vector-Borne Infectious Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Public Health Service, U.S. Department of Health and Human Services, Fort Collins, Colorado, the Parma Community General Hospital, Parma, Ohio, and the U. S. Naval Medical Research Institute, Bethesda, and the U.S. Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, USA
- cthe Instituto Nacional de Salud, Hospital Naval and the U.S. Naval Medical Research Institute Detachment, Lima, and the Ministereo de Salud, Iquitos, Peru
- dFrom the Department of Pathology, Center for Tropical Diseases, University of Texas Medical Branch, Galveston, Texas, the Division of Vector-Borne Infectious Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Public Health Service, U.S. Department of Health and Human Services, Fort Collins, Colorado, the Parma Community General Hospital, Parma, Ohio, and the U. S. Naval Medical Research Institute, Bethesda, and the U.S. Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, USA; and the Instituto Nacional de Salud, Hospital Naval and the U.S. Naval Medical Research Institute Detachment, Lima, and the Ministereo de Salud, Iquitos, Peru
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Abstract
This report describes the clinical, laboratory, and epidemiological findings on 27 cases of Mayaro virus (MV) disease, an emerging mosquito-borne viral illness that is endemic in rural areas of tropical South America. MV disease is a nonfatal, dengue-like illness characterized by fever, chills, headache, eye pain, generalized myalgia, arthralgia, diarrhea, vomiting, and rash of 3-5 days' duration. Severe joint pain is a prominent feature of this illness; the arthralgia sometimes persists for months and can be quite incapacitating. Cases of two visitors from the United States, who developed MV disease during visits to eastern Peru, are reported. MV disease and dengue are difficult to differentiate clinically.
TL;DRClinical, laboratory, and epidemiological findings on 27 cases of Mayaro virus (MV) disease, an emerging mosquito-borne viral illness that is endemic in rural areas of tropical South America, are described. (Semantic Scholar)

