Ultra-Short Echo Time 31P 3D MRSI at 3T with Novel Rosette k-space Trajectory
Brian Bozymski, Xin Shen, Ali Çağlar Özen, Serhat İlbey, Albert Thomas, Mark Chiew, Ulrike Dydak, Uzay E. Emir
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Abstract
Feasibility of a novel, rosette trajectory UTE (70 μs) 3D 31P MRSI sequence is tested at 3T in phantoms and in upper leg scan with healthy subject. Braino phantom, proton resolution phantom, and highly concentrated 31P phantom test demonstrated proper reconstruction and metabolite localization. In vivo calculations of acquired PCr and β-ATP signals showed competitive SNR across 20 voxels of interest. With further acceleration, the sequence may serve as a superior alternative to conventional weighted 3D MRSI, allowing for greater SNR or resolution in briefer times. Notably, this unprecedentedly short UTE 31P MRSI intrinsically avoids baseline and phasing issues.
TL;DRIn vivo calculations of acquired PCr and β-ATP signals showed competitive SNR across 20 voxels of interest, and this unprecedentedly short UTE 31P MRSI intrinsically avoids baseline and phasing issues. (Semantic Scholar)