peer review Open access
Faculty Opinions recommendation of A functional role for antibodies in tuberculosis.
- aOregon Tuberculosis Research Lab, School of Medicine, Oregon Health & Science University, USA
- ✉Corresponding author
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature2018-05-22 0 citations73 references
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Abstract
While a third of the world carries the burden of tuberculosis, disease control has been hindered by the lack of tools including a rapid, point-of-care diagnostic and a protective vaccine.In many infectious diseases, antibodies (Abs) are powerful biomarkers and important immune mediators.However, in Mycobacterium tuberculosis (Mtb) infection, a discriminatory or protective role for humoral immunity remains unclear.Using an unbiased antibody profiling approach we show that

