Emerging Applications and Innovations in Emulgel Technology for Enhanced Topical Drug Delivery
Kuldeep Singha, Jeetendra Kumar Guptaa, Shamim Khanb, Mohammad Muztabac, Sohi Shaheenad, Jailani. Se f g, Mukesh Chandra Sharmah, Divya Jaini✉
- aDepartment of Pharmacology, Institute of Pharmaceutical Research, GLA University, Mathura Uttar Pradesh, India
- bIIMT College of Medical Sciences, IIMT University, Ganga Nagar, Meerut, Uttar Pradesh, 250001, India
- cDepartment of Pharmacology, Praduman Singh Sikshan Prasikshan Sansthan Pharmacy College, Phutahiya Sansarpur Basti Uttar Pradesh India
- dRIMT University College of Pharmacy, Mandi Gobindgarh India
- eFormulation R&
- fD, Alpha Pharma, KAEC, Rabigh, Kingdom of Saudi Arabia
- gFormulation R&
- hSchool of Pharmacy, Devi Ahilya Vishwavidalaya, Indore, MP, India
- iDepartment of Microbiology, School of Applied and Life Sciences, Uttaranchal University, Dehradun, Uttarakhand, India
- ✉Corresponding author
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Abstract
Abstract: Topical drug delivery systems have garnered significant attention in recent years due to their advantages in localized drug administration, reduced systemic side effects, and enhanced pa-tient compliance. Emulgels, a novel formulation combining the benefits of emulsions and gels, have emerged as a promising approach for improving the topical delivery of anti-inflammatory drugs. This review highlights the evolving trends in emulgel technology, focusing on their unique properties, formulation techniques, and advantages over traditional topical systems. The incorpo-ration of anti-inflammatory drugs into emulgel systems enhances drug solubility, provides sus-tained release, and improves skin penetration, making them highly effective in treating conditions like arthritis, dermatitis, and other inflammatory disorders. Additionally, emerging trends such as the use of bio-based polymers, nanotechnology, and targeted delivery systems are discussed, em-phasizing their potential to revolutionize the topical delivery of anti-inflammatory agents. This article provides a comprehensive overview of the recent advancements in emulgel formulations and their prospects in pharmaceutical applications.