Recent trends in medicinal applications of mercury based organometallic and coordination compounds
Fozia Maqsooda b, Sawsan S. Al-Rawic, Ahmad Hamdy Ibrahimd, Faisal Jamila b, Ayesha Zafara b, Muhammad Adnan Iqbala b✉, Umar Sohail Shoukata b, Mohammad Asade, Sami Ullah Ziab, Farhan Ahmadb, Muhammad Mudasir Atiff
- aDepartment of Chemistry, Organometallic & Coordination Chemistry Laboratory , University of Agriculture Faisalabad , Faisalabad , Pakistan
- bFaculty of Science s , The Superior University-Lahore , Faisalabad Campus , Faisalabad , Pakistan
- cBiology Education Department, Faculty of Education , Tishk International University , 100Mt. St, Near Baz Intersection , Erbil , KRG , Iraq
- dPharmacy Department, Faculty of Pharmacy , Tishk International University , 100Mt. St, Near Baz Intersection , Erbil , KRG , Iraq
- eCenter of Excellence for Advanced Materials Research (CEAMR) , King Abdulaziz University , Jeddah 21589 , Saudi Arabia
- fDepartment of Sciences , Superior University-Lahore, Faisalabad Campus , Faisalabad , Pakistan
- ✉Corresponding author
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Abstract
Abstract Metal-based drugs are finding new medical applications, particularly in antibacterial therapies. Compounds such as Prontosil and ciprofloxacin, as well as its derivatives such as beta-lactam drugs, aminoglycosides, vancomycin, fosfomycin, as well as tetracyclines, play critical roles in the prevention of bacterial and fungal infections. The increasing prevalence of microbial resistance is prompting the use of metal complexes to tackle fungal and bacterial strains. Mercury-based complexes, which are known for their unusual characteristics and reactivity, have received a lot of interest in the field of medicine recently. Additionally, Schiff base complexes are widely used as antifungal, antibacterial, and anticancer drugs, as well as in dye manufacturing. This article discusses current advances in the use of mercury compounds for combating fungus and bacteria, offering information on their efficacy and future applications.
TL;DRCurrent advances in the use of mercury compounds for combating fungus and bacteria are discussed, offering information on their efficacy and future applications. (Semantic Scholar)