article
Adjunctive protein synthesis inhibitor antibiotics for toxin suppression in Staphylococcus aureus infections: a systematic appraisal
Anita Jane Campbella b c, Ravindra Doteld, Christopher C. Blytha b c, Joshua Saul Davise f, Steven Y. C. Tongf g, Asha C Bowena b c f✉
- aPerth Children’s Hospital, 15 Hospital Avenue, Perth, Western Australia, Australia
- bSchool of Medicine, Division of Paediatrics, University of Western Australia, Perth, Western Australia, Australia
- cWesfarmers Centre for Vaccines and Infectious Diseases, Telethon Kids Institute, Perth, Western Australia, Australia
- dCentre for Infectious Diseases and Microbiology, Westmead Hospital, University of Sydney, and Department of Infectious Diseases, Blacktown Hospital, Sydney, New South Wales, Australia
- eDepartment of Infectious Diseases, John Hunter Hospital, Newcastle, New South Wales, Australia
- fGlobal and Tropical Health Division, Menzies School of Health Research, Darwin, Northern Territory, Australia
- gVictorian Infectious Disease Service, The Royal Melbourne Hospital, and The University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, Victoria, Australia
- ✉Corresponding author
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Abstract
Protein synthesis inhibitor antibiotics inhibit synthesis of new proteins, including exotoxins and other important virulence determinants in Staphylococcus aureus. A summary of the literature regarding the use of adjunctive protein synthesis inhibitors for toxin suppression in the setting of S. aureus infections is presented.
TL;DRProtein synthesis inhibitor antibiotics inhibit synthesis of new proteins, including exotoxins and other important virulence determinants in Staphylococcus aureus. (Semantic Scholar)

