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Useful four-carbon synthons en route to monastrol analogs
Amr M. Abdoua b, Samir Botrosc, Rasha A. Hassana c, Mona Monir Kamelc, Douglass F. Tabera d✉, Azza T. Taherc
- aDepartment of Chemistry and Biochemistry, University of Delaware, Newark, DE 19716, USA
- bDepartment of Microbiology and Immunology, National Research Center, Dokki, Giza, Egypt
- cDepartment of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Cairo University, Cairo, Egypt
- dDepartment of Chemistry and Biochemistry, University of Delaware Newark, DE 19716 (USA)
- ✉Corresponding author
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Abstract
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TL;DRA simple protocol has been established for the preparation of a family of crystalline N-aryl γ-hydroxycrotonamides, useful four-carbon synthons, that were evaluated for their anticancer activity employing the NCI 60 cell line panel. (Semantic Scholar)

