Investigation of pyridine-bearing thiazolidinone derivatives as promising inhibitors of thymidine phosphorylase and α-glucosidase: Theoretical and computational approaches to develop multitarget drugs

Shoaib Ahmed Khan^{a b}, Rafaqat Hussain^c✉, Yousaf Khan^b, Tayyiaba Iqbal^a, Saeed Anwar^a✉, Tariq A. Aziz^d✉, Muhammad Irfan Afridi^e, Metab Alharbi^f, Fayez Alghamdi^g

1. ^aDepartment of Chemistry, Abbottabad University of Science and Technology (AUST) Abbottabad, Pakistan
2. ^bDepartment of Chemistry, COMSATS University Islamabad 45550 Islamabad Pakistan
3. ^cCollege of Biology, Hunan University, Changsha, Hunan 410082, PR China
4. ^dLaboratory of Animal Health, Food Hygiene and Quality, Department of Agriculture, University of Ioannina, 47132 Arta, Greece
5. ^eState Key Laboratory of Chemo/Biosensing and Chemometrics, College of Biology, Hunan University, Changsha 410082, Hunan, China
6. ^fDepartment of Pharmacology and Toxicology, College of Pharmacy, King Saud University, P.O. Box 2455, Riyadh 11451, Saudi Arabia
7. ^gDepartment of Pharmacy, Riyadh Security Forces Hospital, Ministry of Interior, Kingdom of Saudi Arabia
8. ✉Corresponding author