Bone Strength Is Preserved Following Bariatric Surgery
Lesley M. Sciboraa b c✉, Hēnry Buchwaldd e, Moira A. Petitf g, Julie M. Hughesh i, Sayeed Ikramuddind e
- aSchool of Kinesiology, University of Minnesota, 1900 University Avenue SE, Minneapolis, MN, USA, 55455, l.scibora@stthomas.edu
- bUniversity of Minnesota
- cUniversity of St. Thomas
- dDepartment of Surgery, University of Minnesota, VCRC, 401 East River Parkway, Minneapolis, MN, USA, 55455
- eDepartment of Surgery, University of Minnesota, Minneapolis, USA
- fActiv8 LLC, 658 Grand Ave S, Suite 204, St. Paul, MN, USA, 55105
- gActiv8 LLC
- hMilitary Performance Division, United States Army Institute of Environmental Medicine, 15 Kansas Street, BLDG 42, Natick, MA, USA, 01760
- iMilitary Performance Division, United States Army Institute of Environmental Medicine, Natick, USA
- ✉Corresponding author
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Abstract
Background: There is an increasing concern that bariatric surgery results in excessive bone loss as demonstrated by studies that use areal bone mineral density (aBMD) outcomes by dual energy X-ray absorptiometry (DXA). Thus, we explored the effect of bariatric surgery on bone mechanical strength. Methods: Bone strength and body composition outcomes were measured in 21 adults (age 45.3 years; BMI 45.7 kg/m(2)) at baseline (pre-surgery) and 3, 6, and 12 months post-surgery. Bone geometry, density and strength were assessed by peripheral quantitative computed tomography (pQCT) at the distal (4 %) sites of the radius and tibia and at the midshaft sites of the tibia (66 %) and radius (50 %). Participants were divided into tertiles (high, medium, and low) of percentage weight loss at 6 months post-surgery. Results: Participants in all three tertiles lost significant body weight by 6 months post-surgery (mean loss -5 to -30 %, all p < 0.05). At 6 months, all tertiles lost significant fat mass (-9 to -51 %, all p < 0.05), but only the high tertile lost significant fat-free mass (-8 %, p < 0.05). Despite a slight increase in tibia bone strength (SSIp) at 3 months (+1.1 %, p < 0.05), estimates of bone strength at the radius and tibia sites did not change at later post-surgical time points regardless of weight loss. Conclusions: Contrary to DXA-based aBMD outcomes in the current literature, these results suggest that bone strength was preserved up to 12 months following bariatric surgery. Future longer-term studies exploring bone strength and geometry are needed to confirm these findings.
TL;DRIt is suggested that bone strength was preserved up to 12 months following bariatric surgery, contrary to DXA-based aBMD outcomes in the current literature. (Semantic Scholar)